| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 4,592,903 | 4,461,878 | -131,025 | 1.40 | 1.53 | +0.12 | sell |
| FMR LLC | 4,366,482 | 4,433,659 | +67,177 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 4,128,428 | 4,258,201 | +129,773 | 0.00 | 0.00 | +0.00 | buy |
| BAILLIE GIFFORD & CO | 3,419,093 | 3,445,309 | +26,216 | 0.01 | 0.01 | +0.00 | buy |
| Opaleye Management Inc. | 3,045,525 | 3,120,000 | +74,475 | 2.47 | 2.37 | -0.10 | buy |
| Telemark Asset Management, LLC | 2,696,411 | 2,696,411 | 0 | 1.22 | 0.97 | -0.25 | hold |
| Casdin Capital, LLC | 2,000,000 | 2,000,000 | 0 | 0.60 | 0.52 | -0.08 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 1,514,392 | 1,562,679 | +48,287 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 1,485,228 | 1,511,283 | +26,055 | 0.00 | 0.00 | +0.00 | buy |
| Assenagon Asset Management S.A. | 1,456,739 | 1,456,739 | 0 | 0.01 | 0.01 | -0.00 | hold |
| FEDERATED HERMES, INC. | 1,340,430 | 1,351,880 | +11,450 | 0.01 | 0.01 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 1,232,173 | 1,299,073 | +66,900 | 0.00 | 0.00 | +0.00 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 1,367,988 | 1,046,676 | -321,312 | 0.02 | 0.02 | -0.00 | sell |
| PARADIGM CAPITAL MANAGEMENT INC/NY | 900,000 | 900,000 | 0 | 0.14 | 0.15 | +0.01 | hold |
| TWO SIGMA ADVISERS, LP | 934,800 | 867,700 | -67,100 | 0.01 | 0.01 | +0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 782,147 | 779,335 | -2,812 | 0.01 | 0.01 | +0.00 | sell |
| NORTHERN TRUST CORP | 613,276 | 591,677 | -21,599 | 0.00 | 0.00 | +0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 583,989 | 531,778 | -52,211 | 0.00 | 0.00 | +0.00 | sell |
| FRED ALGER MANAGEMENT, LLC | 432,989 | 508,095 | +75,106 | 0.01 | 0.01 | +0.00 | buy |
| PRESCOTT GROUP CAPITAL MANAGEMENT, L.L.C. | 530,500 | 453,125 | -77,375 | 0.28 | 0.25 | -0.03 | sell |
| Vivo Capital, LLC | 388,144 | 388,144 | 0 | 0.10 | 0.11 | +0.01 | hold |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 363,986 | +363,986 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 127,593 | 351,546 | +223,953 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 618,955 | 332,866 | -286,089 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 210,817 | 253,305 | +42,488 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 264,539 | 252,028 | -12,511 | 0.00 | 0.00 | +0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 197,000 | 242,000 | +45,000 | 0.01 | 0.02 | +0.00 | buy |
| Private Advisor Group, LLC | 189,486 | 231,341 | +41,855 | 0.00 | 0.01 | +0.00 | buy |
| PLATINUM INVESTMENT MANAGEMENT LTD | 0 | 229,667 | +229,667 | 0.00 | 0.03 | +0.03 | buy |
| GOLDMAN SACHS GROUP INC | 254,949 | 206,320 | -48,629 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 211,734 | 204,554 | -7,180 | 0.00 | 0.00 | +0.00 | sell |
| Informed Momentum Co LLC | 0 | 199,474 | +199,474 | 0.00 | 0.11 | +0.11 | buy |
| ROYAL BANK OF CANADA | 158,185 | 197,261 | +39,076 | 0.00 | 0.00 | +0.00 | buy |
| Empire Financial Management Company, LLC | 182,500 | 187,952 | +5,452 | 0.22 | 0.22 | -0.00 | buy |
| D. E. Shaw & Co., Inc. | 911,138 | 169,578 | -741,560 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 215,427 | 164,576 | -50,851 | 0.00 | 0.00 | -0.00 | sell |
| ENVESTNET ASSET MANAGEMENT INC | 119,762 | 161,649 | +41,887 | 0.00 | 0.00 | +0.00 | buy |
| Aberdeen Group plc | 160,581 | 160,581 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PERKINS CAPITAL MANAGEMENT INC | 46,600 | 159,600 | +113,000 | 0.12 | 0.46 | +0.34 | buy |
| Cubist Systematic Strategies, LLC | 65,820 | 158,194 | +92,374 | 0.00 | 0.01 | +0.00 | buy |
| Engineers Gate Manager LP | 211,267 | 154,968 | -56,299 | 0.02 | 0.01 | -0.00 | sell |
| WHITE PINE CAPITAL LLC | 148,240 | 152,144 | +3,904 | 0.17 | 0.17 | -0.01 | buy |
| STRS OHIO | 252,500 | 145,300 | -107,200 | 0.00 | 0.00 | -0.00 | sell |
| STIFEL FINANCIAL CORP | 0 | 138,515 | +138,515 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 188,969 | 130,067 | -58,902 | 0.00 | 0.00 | -0.00 | sell |
| LPL Financial LLC | 87,566 | 117,415 | +29,849 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 101,733 | 104,577 | +2,844 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 110,110 | 104,010 | -6,100 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 18,335 | 101,771 | +83,436 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 35,681 | 98,182 | +62,501 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 42,749 | 84,715 | +41,966 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 13,000 | 80,500 | +67,500 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 107,492 | 77,609 | -29,883 | 0.00 | 0.00 | -0.00 | sell |
| UBS Group AG | 69,946 | 73,330 | +3,384 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 162,507 | 69,744 | -92,763 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 0 | 59,857 | +59,857 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 113,462 | 51,413 | -62,049 | 0.00 | 0.00 | -0.00 | sell |
| GSA CAPITAL PARTNERS LLP | 837,036 | 49,630 | -787,406 | 0.21 | 0.01 | -0.20 | sell |
| OCCUDO QUANTITATIVE STRATEGIES LP | 30,661 | 46,600 | +15,939 | 0.01 | 0.03 | +0.02 | buy |
| JPMORGAN CHASE & CO | 107,201 | 43,414 | -63,787 | 0.00 | 0.00 | -0.00 | sell |
| MSH Capital Advisors LLC | 39,164 | 39,164 | 0 | 0.04 | 0.05 | +0.00 | hold |
| Centiva Capital, LP | 31,195 | 37,568 | +6,373 | 0.01 | 0.01 | +0.00 | buy |
| BLAIR WILLIAM & CO/IL | 36,005 | 36,005 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ALGERT GLOBAL LLC | 63,070 | 35,487 | -27,583 | 0.01 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 40,114 | 34,950 | -5,164 | 0.00 | 0.00 | -0.00 | sell |
| MetLife Investment Management, LLC | 34,375 | 34,925 | +550 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 105,761 | 34,867 | -70,894 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN INTERNATIONAL GROUP, INC. | 34,652 | 34,358 | -294 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 48,415 | 32,186 | -16,229 | 0.00 | 0.00 | -0.00 | sell |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 36,900 | 29,973 | -6,927 | 0.00 | 0.00 | -0.00 | sell |
| FRANKLIN RESOURCES INC | 29,456 | 29,456 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 18,105 | 28,500 | +10,395 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 29,048 | 26,047 | -3,001 | 0.00 | 0.00 | +0.00 | sell |
| WELLS FARGO & COMPANY/MN | 23,279 | 25,372 | +2,093 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 0 | 24,978 | +24,978 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 28,677 | 22,311 | -6,366 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 31,442 | 21,252 | -10,190 | 0.00 | 0.00 | -0.00 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 24,115 | 21,037 | -3,078 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 18,480 | 20,794 | +2,314 | 0.00 | 0.00 | +0.00 | buy |
| Dynamic Technology Lab Private Ltd | 19,969 | 18,283 | -1,686 | 0.01 | 0.01 | +0.00 | sell |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 5,208 | 17,004 | +11,796 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 16,843 | 16,843 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PRUDENTIAL FINANCIAL INC | 0 | 16,134 | +16,134 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 69,910 | 15,551 | -54,359 | 0.05 | 0.01 | -0.04 | sell |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 16,073 | 14,171 | -1,902 | 0.00 | 0.00 | -0.00 | sell |
| HSBC HOLDINGS PLC | 11,896 | 13,965 | +2,069 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 10,166 | 13,168 | +3,002 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 11,538 | 12,526 | +988 | 0.00 | 0.00 | +0.00 | buy |
| Miller Investment Management, LP | 11,693 | 11,693 | 0 | 0.01 | 0.01 | +0.00 | hold |
| SEI INVESTMENTS CO | 11,004 | 10,941 | -63 | 0.00 | 0.00 | +0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 11,475 | 7,010 | -4,465 | 0.00 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 6,162 | 6,162 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Quantbot Technologies LP | 3,572 | 5,472 | +1,900 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 4,645 | 4,645 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Allspring Global Investments Holdings, LLC | 46,489 | 4,141 | -42,348 | 0.00 | 0.00 | -0.00 | sell |
| CIBC Private Wealth Group LLC | 0 | 3,400 | +3,400 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 1,643 | 2,189 | +546 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 6,109 | 2,084 | -4,025 | 0.00 | 0.00 | -0.00 | sell |
| METROPOLITAN LIFE INSURANCE CO/NY | 3,389 | 1,926 | -1,463 | 0.00 | 0.00 | -0.00 | sell |
| Salomon & Ludwin, LLC | 1,500 | 1,500 | 0 | 0.00 | 0.00 | +0.00 | hold |