| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Ovata Capital Management Ltd | 24,677,000 | 68,136,000 | +43,459,000 | 3.48 | 11.60 | +8.12 | buy |
| SSI INVESTMENT MANAGEMENT LLC | 0 | 14,086,000 | +14,086,000 | 1.16 | 1.38 | +0.22 | buy |
| PICTON MAHONEY ASSET MANAGEMENT | 4,000,000 | 9,000,000 | +5,000,000 | 0.06 | 0.13 | +0.07 | buy |
| ABSOLUTE INVESTMENT ADVISERS, LLC | 7,500,000 | 8,350,000 | +850,000 | 1.14 | 1.39 | +0.25 | buy |
| BNP Paribas Asset Management Holding S.A. | 2,000,000 | 7,900,000 | +5,900,000 | 0.00 | 0.01 | +0.01 | buy |
| BlackRock, Inc. | 5,451,241 | 5,591,700 | +140,459 | 0.02 | 0.02 | +0.00 | buy |
| BNP Paribas Asset Management Holding S.A. | 3,200,000 | 3,200,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| STATE OF WISCONSIN INVESTMENT BOARD | 3,000,000 | 3,000,000 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Capital World Investors | 2,666,602 | 2,673,376 | +6,774 | 0.06 | 0.07 | +0.01 | buy |
| LSV ASSET MANAGEMENT | 2,455,957 | 2,386,840 | -69,117 | 0.91 | 0.97 | +0.06 | sell |
| FMR LLC | 800,925 | 2,275,762 | +1,474,837 | 0.01 | 0.02 | +0.02 | buy |
| FRANKLIN RESOURCES INC | 1,818,911 | 1,958,940 | +140,029 | 0.08 | 0.09 | +0.01 | buy |
| DIMENSIONAL FUND ADVISORS LP | 2,623,303 | 1,895,215 | -728,088 | 0.09 | 0.07 | -0.02 | sell |
| STATE STREET CORP | 1,837,793 | 1,891,646 | +53,853 | 0.01 | 0.01 | +0.00 | buy |
| EcoR1 Capital, LLC | 1,706,469 | 1,706,469 | 0 | 13.24 | 13.79 | +0.55 | hold |
| Bank of New York Mellon Corp | 1,161,857 | 1,679,371 | +517,514 | 0.03 | 0.06 | +0.02 | buy |
| FULLER & THALER ASSET MANAGEMENT, INC. | 1,677,132 | 1,676,142 | -990 | 0.96 | 1.07 | +0.10 | sell |
| AMERIPRISE FINANCIAL INC | 1,521,090 | 1,608,476 | +87,386 | 0.06 | 0.07 | +0.01 | buy |
| AQR CAPITAL MANAGEMENT LLC | 877,267 | 1,338,458 | +461,191 | 0.08 | 0.11 | +0.04 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,202,711 | 1,262,511 | +59,800 | 0.15 | 0.18 | +0.03 | buy |
| CITADEL ADVISORS LLC | 311,120 | 1,259,444 | +948,324 | 0.04 | 0.17 | +0.13 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,197,236 | 1,237,617 | +40,381 | 0.01 | 0.01 | +0.00 | buy |
| JPMORGAN CHASE & CO | 1,044,642 | 1,204,353 | +159,711 | 0.01 | 0.01 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 915,144 | 1,014,800 | +99,656 | 0.01 | 0.01 | +0.00 | buy |
| Swedbank AB | 1,102,974 | 992,108 | -110,866 | 0.18 | 0.20 | +0.02 | sell |
| BNP Paribas Asset Management Holding S.A. | 706,047 | 885,201 | +179,154 | 0.14 | 0.19 | +0.06 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 836,774 | 819,374 | -17,400 | 0.22 | 0.24 | +0.02 | sell |
| MIZUHO SECURITIES USA LLC | 0 | 750,000 | +750,000 | 0.00 | 0.02 | +0.02 | buy |
| Holocene Advisors, LP | 589,735 | 733,905 | +144,170 | 0.21 | 0.34 | +0.12 | buy |
| MORGAN STANLEY | 639,179 | 698,738 | +59,559 | 0.01 | 0.01 | +0.00 | buy |
| Allianz Asset Management GmbH | 598,832 | 610,297 | +11,465 | 0.12 | 0.13 | +0.02 | buy |
| Sofinnova Investments, Inc. | 959,860 | 598,327 | -361,533 | 7.04 | 5.67 | -1.37 | sell |
| GMT CAPITAL CORP | 638,500 | 581,000 | -57,500 | 5.66 | 5.01 | -0.65 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 547,743 | 535,062 | -12,681 | 0.08 | 0.09 | +0.01 | sell |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 182,201 | 517,284 | +335,083 | 0.33 | 1.01 | +0.68 | buy |
| Pacer Advisors, Inc. | 647,084 | 503,013 | -144,071 | 0.17 | 0.34 | +0.17 | sell |
| Pacer Advisors, Inc. | 647,084 | 503,013 | -144,071 | 0.17 | 0.00 | -0.17 | sell |
| Boston Trust Walden Corp | 393,911 | 488,661 | +94,750 | 0.51 | 0.76 | +0.25 | buy |
| NORTHERN TRUST CORP | 476,871 | 488,522 | +11,651 | 0.01 | 0.01 | +0.00 | buy |
| GOLDENTREE ASSET MANAGEMENT LP | 420,341 | 475,550 | +55,209 | 3.87 | 5.32 | +1.46 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 112,560 | 458,014 | +345,454 | 0.00 | 0.02 | +0.01 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 424,290 | 440,510 | +16,220 | 0.01 | 0.01 | +0.00 | buy |
| Polaris Capital Management, LLC | 432,466 | 415,366 | -17,100 | 6.10 | 6.42 | +0.33 | sell |
| Alyeska Investment Group, L.P. | 323,384 | 411,015 | +87,631 | 0.16 | 0.22 | +0.06 | buy |
| SYSTEMATIC FINANCIAL MANAGEMENT LP | 396,877 | 407,114 | +10,237 | 1.59 | 1.76 | +0.17 | buy |
| GW&K Investment Management, LLC | 427,644 | 371,098 | -56,546 | 0.63 | 0.62 | -0.01 | sell |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 228,642 | 365,451 | +136,809 | 0.08 | 0.15 | +0.07 | buy |
| Point72 Asset Management, L.P. | 175,000 | 358,634 | +183,634 | 0.05 | 0.12 | +0.07 | buy |
| UBS Group AG | 472,952 | 357,203 | -115,749 | 0.02 | 0.01 | -0.00 | sell |
| Nuveen, LLC | 381,937 | 346,148 | -35,789 | 0.02 | 0.02 | +0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 291,359 | 328,657 | +37,298 | 0.02 | 0.03 | +0.01 | buy |
| Assenagon Asset Management S.A. | 0 | 320,000 | +320,000 | 0.00 | 0.10 | +0.10 | buy |
| Bank of New York Mellon Corp | 300,000 | 300,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Bank of New York Mellon Corp | 300,000 | 300,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| D. E. Shaw & Co., Inc. | 199,302 | 298,090 | +98,788 | 0.03 | 0.04 | +0.02 | buy |
| Qube Research & Technologies Ltd | 500,486 | 262,553 | -237,933 | 0.12 | 0.07 | -0.05 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 249,678 | 256,598 | +6,920 | 0.02 | 0.03 | +0.01 | buy |
| GOLDMAN SACHS GROUP INC | 174,477 | 250,321 | +75,844 | 0.00 | 0.01 | +0.00 | buy |
| Rockefeller Capital Management L.P. | 265,056 | 249,174 | -15,882 | 0.08 | 0.08 | +0.00 | sell |
| Invesco Ltd. | 191,296 | 244,763 | +53,467 | 0.00 | 0.01 | +0.00 | buy |
| BANK OF MONTREAL /CAN/ | 223,321 | 239,265 | +15,944 | 0.02 | 0.02 | +0.00 | buy |
| THOMPSON SIEGEL & WALMSLEY LLC | 290,200 | 233,694 | -56,506 | 0.83 | 0.78 | -0.05 | sell |
| SEI INVESTMENTS CO | 231,000 | 231,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| JANE STREET GROUP, LLC | 87,110 | 223,615 | +136,505 | 0.02 | 0.05 | +0.03 | buy |
| LOOMIS SAYLES & CO L P | 116,447 | 205,905 | +89,458 | 0.02 | 0.05 | +0.03 | buy |
| SG Americas Securities, LLC | 136,024 | 199,705 | +63,681 | 0.03 | 0.04 | +0.01 | buy |
| Quantinno Capital Management LP | 174,358 | 191,286 | +16,928 | 0.06 | 0.06 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 177,336 | 184,464 | +7,128 | 0.01 | 0.01 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 137,550 | 178,779 | +41,229 | 0.26 | 0.34 | +0.08 | buy |
| PFM Health Sciences, LP | 50,511 | 178,144 | +127,633 | 0.87 | 3.54 | +2.67 | buy |
| Jefferies Financial Group Inc. | 3,500 | 175,599 | +172,099 | 0.00 | 0.40 | +0.40 | buy |
| Pictet Asset Management Holding SA | 184,696 | 173,250 | -11,446 | 0.03 | 0.03 | +0.00 | sell |
| PERCEPTIVE ADVISORS LLC | 170,000 | 170,000 | 0 | 0.53 | 0.63 | +0.11 | hold |
| Retirement Systems of Alabama | 167,698 | 169,265 | +1,567 | 0.09 | 0.11 | +0.01 | buy |
| Krensavage Asset Management, LLC | 167,816 | 167,816 | 0 | 10.08 | 12.41 | +2.33 | hold |
| RHUMBLINE ADVISERS | 158,234 | 164,542 | +6,308 | 0.02 | 0.03 | +0.00 | buy |
| Saturn V Capital Management LP | 248,070 | 162,961 | -85,109 | 7.74 | 5.58 | -2.16 | sell |
| WEDGE CAPITAL MANAGEMENT L L P/NC | 188,878 | 160,006 | -28,872 | 0.58 | 0.56 | -0.02 | sell |
| Tri Locum Partners LP | 0 | 158,663 | +158,663 | 0.00 | 4.21 | +4.21 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 148,323 | 147,764 | -559 | 0.01 | 0.01 | +0.00 | sell |
| SEI INVESTMENTS CO | 110,400 | 147,270 | +36,870 | 0.02 | 0.03 | +0.01 | buy |
| Legal & General Group Plc | 95,871 | 145,528 | +49,657 | 0.00 | 0.01 | +0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 93,802 | 143,499 | +49,697 | 0.06 | 0.10 | +0.05 | buy |
| &PARTNERS | 142,000 | 141,000 | -1,000 | 0.00 | 0.00 | -0.00 | sell |
| Perpetual Ltd | 154,650 | 140,885 | -13,765 | 0.38 | 0.41 | +0.03 | sell |
| STIFEL FINANCIAL CORP | 122,749 | 139,514 | +16,765 | 0.02 | 0.02 | +0.01 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 130,597 | 135,504 | +4,907 | 0.01 | 0.01 | +0.00 | buy |
| Man Group plc | 78,277 | 135,212 | +56,935 | 0.03 | 0.05 | +0.03 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 90,089 | 134,724 | +44,635 | 0.02 | 0.04 | +0.02 | buy |
| Aristotle Capital Management, LLC | 158,837 | 130,545 | -28,292 | 0.05 | 0.05 | -0.00 | sell |
| CITIGROUP INC | 52,805 | 125,348 | +72,543 | 0.01 | 0.02 | +0.01 | buy |
| CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 112,668 | 124,583 | +11,915 | 0.01 | 0.01 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 96,363 | 123,716 | +27,353 | 0.01 | 0.01 | +0.00 | buy |
| Robeco Institutional Asset Management B.V. | 93,649 | 123,082 | +29,433 | 0.02 | 0.03 | +0.01 | buy |
| DekaBank Deutsche Girozentrale | 115,130 | 115,130 | 0 | 0.02 | 0.04 | +0.01 | hold |
| Aberdeen Group plc | 60,337 | 114,128 | +53,791 | 0.02 | 0.03 | +0.02 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 102,800 | 112,500 | +9,700 | 0.01 | 0.01 | +0.00 | buy |
| Swiss National Bank | 107,700 | 108,200 | +500 | 0.01 | 0.01 | +0.00 | buy |
| KBC Group NV | 103,338 | 102,199 | -1,139 | 0.04 | 0.05 | +0.01 | sell |
| Engineers Gate Manager LP | 100,847 | 92,990 | -7,857 | 0.20 | 0.22 | +0.02 | sell |