| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VAN ECK ASSOCIATES CORP | 24,467,240 | 25,125,455 | +658,215 | 0.12 | 0.17 | +0.05 | buy |
| FMR LLC | 13,624,036 | 21,648,467 | +8,024,431 | 0.04 | 0.09 | +0.05 | buy |
| VANGUARD GROUP INC | 18,175,271 | 17,763,914 | -411,357 | 0.01 | 0.02 | +0.01 | sell |
| Capital World Investors | 16,501,346 | 15,841,296 | -660,050 | 0.11 | 0.17 | +0.05 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 14,788,411 | 14,332,237 | -456,174 | 0.11 | 0.17 | +0.06 | sell |
| JUPITER ASSET MANAGEMENT LTD | 10,781,056 | 10,692,169 | -88,887 | 0.36 | 0.37 | +0.01 | sell |
| Tidal Investments LLC | 8,669,868 | 7,308,892 | -1,360,976 | 0.42 | 0.32 | -0.10 | sell |
| STATE STREET CORP | 8,210,058 | 6,680,188 | -1,529,870 | 0.02 | 0.02 | +0.00 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 5,742,951 | 5,653,767 | -89,184 | 0.05 | 0.05 | +0.00 | sell |
| JPMORGAN CHASE & CO | 4,334,890 | 5,256,283 | +921,393 | 0.02 | 0.03 | +0.01 | buy |
| AMERIPRISE FINANCIAL INC | 2,214,730 | 4,525,434 | +2,310,704 | 0.03 | 0.08 | +0.05 | buy |
| WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 3,879,195 | 4,284,953 | +405,758 | 0.43 | 0.72 | +0.29 | buy |
| Artisan Partners Limited Partnership | 3,805,389 | 3,814,526 | +9,137 | 0.24 | 0.39 | +0.15 | buy |
| T. Rowe Price Investment Management, Inc. | 2,941,202 | 3,392,838 | +451,636 | 0.08 | 0.14 | +0.06 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,185,123 | 3,298,076 | +2,112,953 | 0.01 | 0.03 | +0.02 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 3,098,097 | 3,105,970 | +7,873 | 0.01 | 0.02 | +0.01 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 3,934,900 | 2,933,900 | -1,001,000 | 0.06 | 0.06 | -0.00 | sell |
| TD ASSET MANAGEMENT INC | 2,689,003 | 2,732,376 | +43,373 | 0.01 | 0.01 | +0.00 | buy |
| Champlain Investment Partners, LLC | 2,248,500 | 2,494,480 | +245,980 | 0.58 | 1.03 | +0.44 | buy |
| D. E. Shaw & Co., Inc. | 221,624 | 2,183,545 | +1,961,921 | 0.00 | 0.01 | +0.01 | buy |
| Holocene Advisors, LP | 4,038,634 | 1,869,427 | -2,169,207 | 0.71 | 0.51 | -0.20 | sell |
| MORGAN STANLEY | 1,469,126 | 1,780,084 | +310,958 | 0.00 | 0.01 | +0.00 | buy |
| MACQUARIE GROUP LTD | 1,541,559 | 1,542,872 | +1,313 | 0.07 | 0.11 | +0.04 | buy |
| C WorldWide Group Holding A/S | 1,504,355 | 1,500,829 | -3,526 | 0.69 | 1.06 | +0.37 | sell |
| Bellevue Group AG | 1,158,880 | 1,449,465 | +290,585 | 0.80 | 1.60 | +0.80 | buy |
| MACKENZIE FINANCIAL CORP | 11,535 | 1,405,452 | +1,393,917 | 0.00 | 0.13 | +0.13 | buy |
| Spyglass Capital Management LLC | 1,418,591 | 1,397,093 | -21,498 | 4.39 | 6.25 | +1.86 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,763,545 | 1,339,897 | -423,648 | 0.02 | 0.02 | +0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,247,075 | 1,292,090 | +45,015 | 0.01 | 0.02 | +0.01 | buy |
| SPROTT INC. | 888,202 | 1,288,211 | +400,009 | 0.23 | 0.33 | +0.09 | buy |
| MILLENNIUM MANAGEMENT LLC | 674,856 | 1,238,785 | +563,929 | 0.02 | 0.07 | +0.05 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 1,231,728 | 1,232,119 | +391 | 0.89 | 1.45 | +0.56 | buy |
| GOLDMAN SACHS GROUP INC | 1,027,962 | 1,229,545 | +201,583 | 0.00 | 0.00 | +0.00 | buy |
| BAILLIE GIFFORD & CO | 1,426,617 | 1,209,501 | -217,116 | 0.05 | 0.06 | +0.01 | sell |
| Ensign Peak Advisors, Inc | 1,815,137 | 1,201,475 | -613,662 | 0.14 | 0.14 | +0.00 | sell |
| Rock Springs Capital Management LP | 1,081,500 | 1,147,500 | +66,000 | 1.38 | 2.54 | +1.16 | buy |
| GOLDMAN SACHS GROUP INC | 1,067,073 | 1,088,843 | +21,770 | 0.01 | 0.01 | +0.01 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 1,142,776 | 1,049,935 | -92,841 | 0.04 | 0.05 | +0.01 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 1,303,887 | 1,049,256 | -254,631 | 0.03 | 0.04 | +0.01 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,031,116 | 990,972 | -40,144 | 0.01 | 0.01 | +0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 958,369 | 960,592 | +2,223 | 0.01 | 0.02 | +0.01 | buy |
| DEUTSCHE BANK AG\ | 814,477 | 916,872 | +102,395 | 0.02 | 0.03 | +0.01 | buy |
| DIMENSIONAL FUND ADVISORS LP | 963,888 | 915,255 | -48,633 | 0.00 | 0.00 | -0.00 | sell |
| JENNISON ASSOCIATES LLC | 915,434 | 884,659 | -30,775 | 0.02 | 0.04 | +0.01 | sell |
| NORTHERN TRUST CORP | 1,038,425 | 882,841 | -155,584 | 0.01 | 0.01 | +0.00 | sell |
| JPMORGAN CHASE & CO | 980,372 | 856,835 | -123,537 | 0.00 | 0.00 | -0.00 | sell |
| MORGAN STANLEY | 972,213 | 849,958 | -122,255 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 1,153,343 | 831,378 | -321,965 | 0.00 | 0.01 | +0.00 | sell |
| FIRST TRUST ADVISORS LP | 508,911 | 827,621 | +318,710 | 0.02 | 0.05 | +0.03 | buy |
| Bank of New York Mellon Corp | 785,023 | 812,760 | +27,737 | 0.01 | 0.01 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 1,002,784 | 803,376 | -199,408 | 0.01 | 0.01 | +0.00 | sell |
| PEREGRINE CAPITAL MANAGEMENT LLC | 768,640 | 764,218 | -4,422 | 0.95 | 1.57 | +0.62 | sell |
| AMERICAN CENTURY COMPANIES INC | 167,500 | 720,423 | +552,923 | 0.00 | 0.00 | +0.00 | buy |
| NORGES BANK | 1,242,102 | 680,777 | -561,325 | 0.01 | 0.01 | -0.00 | sell |
| ORBIMED ADVISORS LLC | 672,416 | 679,816 | +7,400 | 0.56 | 0.85 | +0.28 | buy |
| Nikko Asset Management Americas, Inc. | 721,088 | 678,468 | -42,620 | 0.35 | 0.52 | +0.17 | sell |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 364,391 | 670,717 | +306,326 | 0.02 | 0.05 | +0.03 | buy |
| Casdin Capital, LLC | 650,000 | 650,000 | 0 | 2.10 | 2.95 | +0.86 | hold |
| BAMCO INC /NY/ | 628,000 | 628,000 | 0 | 0.08 | 0.11 | +0.04 | hold |
| JANE STREET GROUP, LLC | 358,221 | 617,658 | +259,437 | 0.00 | 0.00 | +0.00 | buy |
| AXA S.A. | 614,952 | 615,942 | +990 | 0.08 | 0.12 | +0.05 | buy |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 600,000 | 600,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 705,468 | 591,210 | -114,258 | 0.30 | 0.38 | +0.08 | sell |
| Avidity Partners Management LP | 338,500 | 588,000 | +249,500 | 0.61 | 2.04 | +1.44 | buy |
| CITADEL ADVISORS LLC | 218,621 | 579,428 | +360,807 | 0.00 | 0.00 | +0.00 | buy |
| Swiss National Bank | 535,080 | 547,680 | +12,600 | 0.02 | 0.02 | +0.01 | buy |
| Eagle Health Investments LP | 544,200 | 544,200 | 0 | 4.11 | 7.15 | +3.04 | hold |
| HighTower Advisors, LLC | 507,396 | 506,347 | -1,049 | 0.03 | 0.05 | +0.02 | sell |
| PRIMECAP MANAGEMENT CO/CA/ | 496,300 | 496,300 | 0 | 0.02 | 0.02 | +0.01 | hold |
| Legal & General Group Plc | 806,290 | 486,106 | -320,184 | 0.01 | 0.01 | -0.00 | sell |
| TD ASSET MANAGEMENT INC | 362,974 | 477,756 | +114,782 | 0.01 | 0.03 | +0.01 | buy |
| Swiss National Bank | 476,100 | 476,100 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Rhenman & Partners Asset Management AB | 145,000 | 465,000 | +320,000 | 0.59 | 2.57 | +1.98 | buy |
| Candriam S.C.A. | 212,527 | 456,591 | +244,064 | 0.05 | 0.18 | +0.12 | buy |
| NATIONAL BANK OF CANADA /FI/ | 438,794 | 453,869 | +15,075 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 361,500 | 451,183 | +89,683 | 0.02 | 0.03 | +0.02 | buy |
| WASATCH ADVISORS LP | 507,187 | 437,873 | -69,314 | 0.11 | 0.15 | +0.03 | sell |
| ArrowMark Colorado Holdings LLC | 0 | 419,959 | +419,959 | 0.00 | 0.37 | +0.37 | buy |
| Granahan Investment Management, LLC | 0 | 410,241 | +410,241 | 0.00 | 1.10 | +1.10 | buy |
| Iron Triangle Partners LP | 0 | 399,871 | +399,871 | 0.00 | 3.83 | +3.83 | buy |
| Erste Asset Management GmbH | 306,132 | 392,139 | +86,007 | 0.17 | 0.32 | +0.15 | buy |
| Woodline Partners LP | 56,460 | 391,455 | +334,995 | 0.02 | 0.23 | +0.20 | buy |
| TWO SIGMA INVESTMENTS, LP | 1,112,518 | 386,294 | -726,224 | 0.01 | 0.00 | -0.01 | sell |
| SOROS FUND MANAGEMENT LLC | 225,000 | 378,590 | +153,590 | 0.21 | 0.51 | +0.30 | buy |
| Skandinaviska Enskilda Banken AB (publ) | 369,729 | 369,729 | 0 | 0.07 | 0.12 | +0.04 | hold |
| BLAIR WILLIAM & CO/IL | 446,686 | 357,811 | -88,875 | 0.06 | 0.07 | +0.01 | sell |
| Squarepoint Ops LLC | 0 | 353,824 | +353,824 | 0.00 | 0.00 | +0.00 | buy |
| U S GLOBAL INVESTORS INC | 0 | 350,000 | +350,000 | 0.00 | 0.13 | +0.13 | buy |
| Invesco Ltd. | 0 | 336,247 | +336,247 | 0.00 | 0.00 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 210,513 | 335,705 | +125,192 | 0.04 | 0.11 | +0.07 | buy |
| CITIGROUP INC | 383,806 | 331,661 | -52,145 | 0.02 | 0.02 | +0.01 | sell |
| SEI INVESTMENTS CO | 308,325 | 330,270 | +21,945 | 0.02 | 0.03 | +0.01 | buy |
| Baird Financial Group, Inc. | 283,374 | 326,935 | +43,561 | 0.02 | 0.04 | +0.02 | buy |
| GUGGENHEIM CAPITAL LLC | 324,490 | 325,789 | +1,299 | 0.01 | 0.01 | +0.00 | buy |
| UBS Group AG | 429,145 | 309,186 | -119,959 | 0.01 | 0.01 | +0.00 | sell |
| EULAV Asset Management | 285,000 | 305,000 | +20,000 | 0.33 | 0.51 | +0.18 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 326,910 | 299,668 | -27,242 | 0.00 | 0.01 | +0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 312,778 | 296,375 | -16,403 | 0.02 | 0.03 | +0.01 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 290,594 | 295,673 | +5,079 | 0.02 | 0.02 | +0.01 | buy |
| BRAIDWELL LP | 1,141,678 | 286,178 | -855,500 | 1.51 | 0.55 | -0.96 | sell |