| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| MORGAN STANLEY | 1,184,709 | 2,641,892 | +1,457,183 | 0.00 | 0.00 | +0.00 | buy |
| BAKER BROS. ADVISORS LP | 97,079 | 1,097,079 | +1,000,000 | 0.01 | 0.08 | +0.07 | buy |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 2,566,951 | 3,502,000 | +935,049 | 1.20 | 0.95 | -0.25 | buy |
| Nantahala Capital Management, LLC | 0 | 629,749 | +629,749 | 0.00 | 0.35 | +0.35 | buy |
| MPM BioImpact LLC | 1,020,559 | 1,618,265 | +597,706 | 1.82 | 1.86 | +0.03 | buy |
| MYDA Advisors LLC | 0 | 460,381 | +460,381 | 0.00 | 1.09 | +1.09 | buy |
| FEDERATED HERMES, INC. | 0 | 414,497 | +414,497 | 0.00 | 0.01 | +0.01 | buy |
| MILLENNIUM MANAGEMENT LLC | 336,909 | 747,147 | +410,238 | 0.00 | 0.00 | +0.00 | buy |
| Prosight Management, LP | 1,088,706 | 1,480,000 | +391,294 | 3.83 | 3.24 | -0.59 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 352,957 | +352,957 | 0.00 | 0.01 | +0.01 | buy |
| Jump Financial, LLC | 0 | 253,723 | +253,723 | 0.00 | 0.03 | +0.03 | buy |
| STATE STREET CORP | 3,458,079 | 3,705,461 | +247,382 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,752,975 | 1,994,044 | +241,069 | 0.00 | 0.00 | -0.00 | buy |
| FRANKLIN RESOURCES INC | 653,559 | 870,308 | +216,749 | 0.00 | 0.00 | -0.00 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 0 | 205,378 | +205,378 | 0.00 | 0.02 | +0.02 | buy |
| BANK OF AMERICA CORP /DE/ | 224,311 | 421,487 | +197,176 | 0.00 | 0.00 | -0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 195,793 | +195,793 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 802,785 | 995,690 | +192,905 | 0.00 | 0.00 | -0.00 | buy |
| BlackRock, Inc. | 7,097,287 | 7,274,234 | +176,947 | 0.00 | 0.00 | -0.00 | buy |
| Sovran Advisors, LLC | 150,767 | 323,091 | +172,324 | 0.22 | 0.27 | +0.04 | buy |
| NORDEA INVESTMENT MANAGEMENT AB | 127,270 | 254,405 | +127,135 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 218,519 | 338,474 | +119,955 | 0.00 | 0.00 | -0.00 | buy |
| Mirador Capital Partners LP | 84,529 | 203,829 | +119,300 | 0.19 | 0.24 | +0.05 | buy |
| SYNOVUS FINANCIAL CORP | 163,893 | 278,450 | +114,557 | 0.03 | 0.02 | -0.00 | buy |
| CITIGROUP INC | 123,415 | 234,178 | +110,763 | 0.00 | 0.00 | -0.00 | buy |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 4,714,610 | 4,820,701 | +106,091 | 0.26 | 0.16 | -0.10 | buy |
| TANG CAPITAL MANAGEMENT LLC | 750,000 | 850,000 | +100,000 | 0.62 | 0.31 | -0.31 | buy |
| AQR CAPITAL MANAGEMENT LLC | 65,864 | 163,622 | +97,758 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 515,528 | 610,089 | +94,561 | 0.00 | 0.00 | -0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 49,720 | 128,471 | +78,751 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 569,963 | 647,830 | +77,867 | 0.00 | 0.00 | -0.00 | buy |
| AlphaQuest LLC | 21,686 | 96,391 | +74,705 | 0.04 | 0.07 | +0.03 | buy |
| Verition Fund Management LLC | 25,967 | 99,664 | +73,697 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 220,142 | 287,088 | +66,946 | 0.03 | 0.02 | -0.01 | buy |
| SG Americas Securities, LLC | 54,921 | 116,571 | +61,650 | 0.00 | 0.00 | -0.00 | buy |
| Squarepoint Ops LLC | 0 | 53,476 | +53,476 | 0.00 | 0.00 | +0.00 | buy |
| EntryPoint Capital, LLC | 24,903 | 76,419 | +51,516 | 0.13 | 0.23 | +0.10 | buy |
| AXQ CAPITAL, LP | 0 | 49,546 | +49,546 | 0.00 | 0.13 | +0.13 | buy |
| Legal & General Group Plc | 75,454 | 122,627 | +47,173 | 0.00 | 0.00 | -0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 73,760 | 119,465 | +45,705 | 0.00 | 0.00 | -0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 139,572 | 184,692 | +45,120 | 0.00 | 0.00 | -0.00 | buy |
| Main Management ETF Advisors, LLC | 29,904 | 74,972 | +45,068 | 0.02 | 0.02 | +0.01 | buy |
| NORGES BANK | 0 | 44,294 | +44,294 | 0.00 | 0.00 | +0.00 | buy |
| JENNISON ASSOCIATES LLC | 70,304 | 114,580 | +44,276 | 0.00 | 0.00 | -0.00 | buy |
| Invesco Ltd. | 357,840 | 400,969 | +43,129 | 0.00 | 0.00 | -0.00 | buy |
| VANGUARD GROUP INC | 6,577,595 | 6,617,784 | +40,189 | 0.00 | 0.00 | -0.00 | buy |
| Hudson Bay Capital Management LP | 113,500 | 151,200 | +37,700 | 0.01 | 0.01 | -0.00 | buy |
| Trexquant Investment LP | 0 | 37,613 | +37,613 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 663,152 | 700,301 | +37,149 | 0.00 | 0.00 | -0.00 | buy |
| TWINBEECH CAPITAL LP | 0 | 36,649 | +36,649 | 0.00 | 0.00 | +0.00 | buy |
| COMERICA BANK | 780,380 | 815,989 | +35,609 | 0.04 | 0.02 | -0.02 | buy |
| Privium Fund Management B.V. | 397,650 | 432,760 | +35,110 | 1.13 | 0.75 | -0.38 | buy |
| THOMPSON SIEGEL & WALMSLEY LLC | 12,747 | 46,747 | +34,000 | 0.00 | 0.01 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 0 | 32,096 | +32,096 | 0.00 | 0.09 | +0.09 | buy |
| Capula Management Ltd | 0 | 31,654 | +31,654 | 0.00 | 0.00 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 211,400 | 241,800 | +30,400 | 0.55 | 0.31 | -0.24 | buy |
| Campbell & CO Investment Adviser LLC | 59,969 | 90,084 | +30,115 | 0.06 | 0.05 | -0.01 | buy |
| Dynamic Technology Lab Private Ltd | 0 | 28,370 | +28,370 | 0.00 | 0.03 | +0.03 | buy |
| Bridgefront Capital, LLC | 0 | 25,709 | +25,709 | 0.00 | 0.05 | +0.05 | buy |
| QUADRANT CAPITAL GROUP LLC | 1,235 | 26,825 | +25,590 | 0.00 | 0.01 | +0.01 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 24,632 | +24,632 | 0.00 | 0.01 | +0.01 | buy |
| Entropy Technologies, LP | 0 | 24,612 | +24,612 | 0.00 | 0.02 | +0.02 | buy |
| IEQ CAPITAL, LLC | 0 | 24,275 | +24,275 | 0.00 | 0.00 | +0.00 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0 | 21,406 | +21,406 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 21,027 | +21,027 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 656,090 | 675,481 | +19,391 | 0.00 | 0.00 | -0.00 | buy |
| PIER 88 INVESTMENT PARTNERS LLC | 37,500 | 56,820 | +19,320 | 0.09 | 0.07 | -0.02 | buy |
| TUDOR INVESTMENT CORP ET AL | 31,125 | 50,137 | +19,012 | 0.00 | 0.00 | -0.00 | buy |
| Virtu Financial LLC | 0 | 18,630 | +18,630 | 0.00 | 0.00 | +0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 18,047 | +18,047 | 0.00 | 0.02 | +0.02 | buy |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0 | 17,400 | +17,400 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 0 | 17,102 | +17,102 | 0.00 | 0.00 | +0.00 | buy |
| Ethic Inc. | 0 | 16,474 | +16,474 | 0.00 | 0.00 | +0.00 | buy |
| INTRUST BANK NA | 0 | 15,811 | +15,811 | 0.00 | 0.01 | +0.01 | buy |
| Bank of New York Mellon Corp | 194,182 | 209,967 | +15,785 | 0.00 | 0.00 | -0.00 | buy |
| ALGERT GLOBAL LLC | 40,060 | 55,510 | +15,450 | 0.01 | 0.01 | -0.00 | buy |
| PFG Investments, LLC | 0 | 13,400 | +13,400 | 0.00 | 0.01 | +0.01 | buy |
| HARBOR CAPITAL ADVISORS, INC. | 165,127 | 178,236 | +13,109 | 0.09 | 0.05 | -0.04 | buy |
| Virtus Investment Advisers, LLC | 0 | 13,058 | +13,058 | 0.00 | 0.02 | +0.02 | buy |
| DARK FOREST CAPITAL MANAGEMENT LP | 0 | 13,019 | +13,019 | 0.00 | 0.00 | +0.00 | buy |
| Magnetar Financial LLC | 0 | 12,877 | +12,877 | 0.00 | 0.00 | +0.00 | buy |
| Powell Investment Advisors, LLC | 0 | 12,500 | +12,500 | 0.00 | 0.04 | +0.04 | buy |
| AMERIPRISE FINANCIAL INC | 0 | 12,384 | +12,384 | 0.00 | 0.00 | +0.00 | buy |
| OXFORD ASSET MANAGEMENT LLP | 0 | 12,309 | +12,309 | 0.00 | 0.04 | +0.04 | buy |
| Hennion & Walsh Asset Management, Inc. | 237,499 | 249,526 | +12,027 | 0.14 | 0.07 | -0.06 | buy |
| LJI Wealth Management, LLC | 0 | 12,000 | +12,000 | 0.00 | 0.02 | +0.02 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 11,432 | +11,432 | 0.00 | 0.00 | +0.00 | buy |
| Graham Capital Management, L.P. | 0 | 11,150 | +11,150 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 189,879 | 200,684 | +10,805 | 0.02 | 0.02 | -0.01 | buy |
| HSBC HOLDINGS PLC | 0 | 10,583 | +10,583 | 0.00 | 0.00 | +0.00 | buy |
| Voss Capital, LP | 421,700 | 432,240 | +10,540 | 0.39 | 0.22 | -0.17 | buy |
| Aster Capital Management (DIFC) Ltd | 0 | 10,259 | +10,259 | 0.00 | 0.02 | +0.02 | buy |
| CWM, LLC | 3,725 | 13,223 | +9,498 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 22,645 | 31,577 | +8,932 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 99,339 | 107,638 | +8,299 | 0.00 | 0.00 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 63,778 | 71,470 | +7,692 | 0.00 | 0.00 | -0.00 | buy |
| ROYAL BANK OF CANADA | 8,612 | 15,856 | +7,244 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 40,374 | 46,588 | +6,214 | 0.00 | 0.00 | -0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 43,241 | 48,718 | +5,477 | 0.01 | 0.00 | -0.00 | buy |
| MetLife Investment Management, LLC | 40,487 | 45,858 | +5,371 | 0.00 | 0.00 | -0.00 | buy |