| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RTW INVESTMENTS, LP | 17,687,772 | 17,687,772 | 0 | 0.62 | 0.63 | +0.01 | hold |
| BlackRock, Inc. | 7,906,071 | 7,834,795 | -71,276 | 0.00 | 0.00 | +0.00 | sell |
| CITIGROUP INC | 5,246,349 | 5,107,708 | -138,641 | 0.01 | 0.01 | -0.00 | sell |
| STATE STREET CORP | 1,700,631 | 4,485,989 | +2,785,358 | 0.00 | 0.00 | +0.00 | buy |
| MAVERICK CAPITAL LTD | 2,513,110 | 3,567,372 | +1,054,262 | 0.09 | 0.15 | +0.05 | buy |
| Newtyn Management, LLC | 2,650,000 | 3,165,900 | +515,900 | 0.98 | 1.21 | +0.23 | buy |
| Nuveen, LLC | 158,012 | 3,128,753 | +2,970,741 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,784,921 | 3,118,124 | +1,333,203 | 0.00 | 0.01 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 703,528 | 3,069,930 | +2,366,402 | 0.00 | 0.01 | +0.00 | buy |
| MARSHALL WACE, LLP | 26,347 | 3,038,715 | +3,012,368 | 0.00 | 0.01 | +0.01 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,120,269 | 2,189,256 | +68,987 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 2,640,518 | 2,169,625 | -470,893 | 0.01 | 0.01 | -0.00 | sell |
| Monaco Asset Management SAM | 2,987,296 | 2,058,303 | -928,993 | 3.11 | 2.34 | -0.77 | sell |
| MORGAN STANLEY | 3,941,377 | 2,020,108 | -1,921,269 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 936,594 | 1,721,116 | +784,522 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 151,432 | 1,298,173 | +1,146,741 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 2,131,929 | 1,097,623 | -1,034,306 | 0.01 | 0.00 | -0.01 | sell |
| FEDERATED HERMES, INC. | 881,249 | 1,023,747 | +142,498 | 0.01 | 0.01 | +0.00 | buy |
| Point72 Asset Management, L.P. | 507,909 | 1,012,126 | +504,217 | 0.00 | 0.01 | +0.00 | buy |
| Opaleye Management Inc. | 955,000 | 955,000 | 0 | 0.44 | 0.45 | +0.01 | hold |
| PRICE T ROWE ASSOCIATES INC /MD/ | 944,873 | 859,874 | -84,999 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 1,475,624 | 796,224 | -679,400 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 744,286 | 724,392 | -19,894 | 0.00 | 0.00 | -0.00 | sell |
| Prosight Management, LP | 743,942 | 683,856 | -60,086 | 0.54 | 0.40 | -0.14 | sell |
| Aberdeen Group plc | 0 | 664,821 | +664,821 | 0.00 | 0.00 | +0.00 | buy |
| Woodline Partners LP | 0 | 641,222 | +641,222 | 0.00 | 0.01 | +0.01 | buy |
| NORTHERN TRUST CORP | 618,654 | 640,840 | +22,186 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 421,174 | 637,174 | +216,000 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 579,507 | 630,125 | +50,618 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 602,580 | 623,354 | +20,774 | 0.00 | 0.00 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 474,866 | 482,079 | +7,213 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 118,200 | 476,478 | +358,278 | 0.01 | 0.03 | +0.02 | buy |
| FMR LLC | 395,275 | 462,630 | +67,355 | 0.00 | 0.00 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 475,800 | 432,500 | -43,300 | 0.12 | 0.09 | -0.03 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | 416,533 | +416,533 | 0.00 | 0.01 | +0.01 | buy |
| Sio Capital Management, LLC | 400,000 | 400,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 193,430 | 385,639 | +192,209 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 38,527 | 381,839 | +343,312 | 0.00 | 0.01 | +0.01 | buy |
| RTW INVESTMENTS, LP | 350,000 | 350,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Invesco Ltd. | 304,437 | 347,543 | +43,106 | 0.00 | 0.00 | +0.00 | buy |
| Velan Capital Investment Management LP | 0 | 294,643 | +294,643 | 0.00 | 0.66 | +0.66 | buy |
| DIMENSIONAL FUND ADVISORS LP | 338,830 | 288,264 | -50,566 | 0.00 | 0.00 | -0.00 | sell |
| Hennion & Walsh Asset Management, Inc. | 309,247 | 287,815 | -21,432 | 0.04 | 0.03 | -0.00 | sell |
| Walleye Capital LLC | 284,345 | 284,345 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 115,165 | 269,206 | +154,041 | 0.00 | 0.00 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 434,409 | 260,809 | -173,600 | 0.02 | 0.01 | -0.01 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 400,706 | 259,007 | -141,699 | 0.00 | 0.00 | -0.00 | sell |
| Privium Fund Management B.V. | 170,146 | 242,146 | +72,000 | 0.11 | 0.18 | +0.07 | buy |
| Bank of New York Mellon Corp | 250,962 | 239,842 | -11,120 | 0.00 | 0.00 | +0.00 | sell |
| Creative Planning | 167,039 | 217,851 | +50,812 | 0.00 | 0.00 | +0.00 | buy |
| M28 Capital Management LP | 385,680 | 210,871 | -174,809 | 0.98 | 1.40 | +0.42 | sell |
| Mariner, LLC | 12,634 | 190,111 | +177,477 | 0.00 | 0.00 | +0.00 | buy |
| PDT Partners, LLC | 220,884 | 186,596 | -34,288 | 0.05 | 0.04 | -0.01 | sell |
| Amitell Capital Pte Ltd | 178,769 | 178,769 | 0 | 0.70 | 1.03 | +0.32 | hold |
| XTX Topco Ltd | 146,400 | 178,027 | +31,627 | 0.01 | 0.01 | -0.00 | buy |
| CWM, LLC | 32,480 | 174,263 | +141,783 | 0.00 | 0.00 | +0.00 | buy |
| LPL Financial LLC | 94,256 | 156,086 | +61,830 | 0.00 | 0.00 | +0.00 | buy |
| MONIMUS CAPITAL MANAGEMENT, LP | 138,012 | 153,728 | +15,716 | 0.32 | 0.15 | -0.17 | buy |
| RAYMOND JAMES FINANCIAL INC | 118,746 | 149,207 | +30,461 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 153,121 | 149,204 | -3,917 | 0.00 | 0.00 | +0.00 | sell |
| Rafferty Asset Management, LLC | 0 | 141,212 | +141,212 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 157,290 | 135,570 | -21,720 | 0.00 | 0.00 | -0.00 | sell |
| Birchview Capital, LP | 0 | 127,025 | +127,025 | 0.00 | 0.26 | +0.26 | buy |
| Engineers Gate Manager LP | 96,009 | 115,168 | +19,159 | 0.00 | 0.01 | +0.00 | buy |
| Virtu Financial LLC | 0 | 113,548 | +113,548 | 0.00 | 0.02 | +0.02 | buy |
| RHUMBLINE ADVISERS | 113,420 | 110,196 | -3,224 | 0.00 | 0.00 | +0.00 | sell |
| BOOTHBAY FUND MANAGEMENT, LLC | 91,642 | 106,399 | +14,757 | 0.01 | 0.01 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 92,795 | 105,594 | +12,799 | 0.00 | 0.00 | +0.00 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 104,828 | 104,828 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TANG CAPITAL MANAGEMENT LLC | 100,000 | 100,000 | 0 | 0.02 | 0.02 | +0.00 | hold |
| Assenagon Asset Management S.A. | 32,515 | 99,026 | +66,511 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 178,926 | 95,180 | -83,746 | 0.01 | 0.00 | -0.00 | sell |
| RICE HALL JAMES & ASSOCIATES, LLC | 84,987 | 91,887 | +6,900 | 0.02 | 0.02 | +0.00 | buy |
| Ballentine Partners, LLC | 97,625 | 89,001 | -8,624 | 0.00 | 0.00 | -0.00 | sell |
| Lion Point Capital, LP | 86,000 | 86,000 | 0 | 1.56 | 1.84 | +0.28 | hold |
| MERCER GLOBAL ADVISORS INC /ADV | 16,046 | 82,548 | +66,502 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 18,230 | 80,868 | +62,638 | 0.00 | 0.00 | +0.00 | buy |
| Virtus Investment Advisers, LLC | 78,474 | 80,438 | +1,964 | 0.07 | 0.08 | +0.00 | buy |
| Cerity Partners LLC | 22,792 | 78,974 | +56,182 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF MONTREAL /CAN/ | 75,310 | 78,558 | +3,248 | 0.00 | 0.00 | +0.00 | buy |
| Quantinno Capital Management LP | 40,397 | 76,248 | +35,851 | 0.00 | 0.00 | +0.00 | buy |
| LMR Partners LLP | 75,731 | 75,731 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Affinity Asset Advisors, LLC | 75,000 | 75,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Marex Group plc | 57,500 | 72,500 | +15,000 | 0.00 | 0.00 | +0.00 | buy |
| Concurrent Investment Advisors, LLC | 68,096 | 70,625 | +2,529 | 0.00 | 0.00 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 102,538 | 68,046 | -34,492 | 0.00 | 0.00 | -0.00 | sell |
| Rockefeller Capital Management L.P. | 64,222 | 67,826 | +3,604 | 0.00 | 0.00 | +0.00 | buy |
| PROFUND ADVISORS LLC | 0 | 63,066 | +63,066 | 0.00 | 0.01 | +0.01 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 95,100 | 61,300 | -33,800 | 0.00 | 0.00 | -0.00 | sell |
| Aquatic Capital Management LLC | 0 | 58,166 | +58,166 | 0.00 | 0.01 | +0.01 | buy |
| AMERICAN CENTURY COMPANIES INC | 0 | 57,562 | +57,562 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 9,204 | 57,382 | +48,178 | 0.00 | 0.01 | +0.01 | buy |
| Russell Investments Group, Ltd. | 10,229 | 54,603 | +44,374 | 0.00 | 0.00 | +0.00 | buy |
| PIER 88 INVESTMENT PARTNERS LLC | 47,880 | 54,200 | +6,320 | 0.04 | 0.05 | +0.01 | buy |
| TUDOR INVESTMENT CORP ET AL | 42,411 | 50,493 | +8,082 | 0.00 | 0.00 | +0.00 | buy |
| Voleon Capital Management LP | 67,981 | 49,794 | -18,187 | 0.01 | 0.00 | -0.00 | sell |
| MetLife Investment Management, LLC | 33,480 | 46,551 | +13,071 | 0.00 | 0.00 | +0.00 | buy |
| WINTON GROUP Ltd | 0 | 42,500 | +42,500 | 0.00 | 0.01 | +0.01 | buy |
| WELLS FARGO & COMPANY/MN | 103,906 | 39,260 | -64,646 | 0.00 | 0.00 | -0.00 | sell |
| BOOTHBAY FUND MANAGEMENT, LLC | 36,912 | 36,912 | 0 | 0.00 | 0.00 | -0.00 | hold |