| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 5,750,000 | 6,200,000 | +450,000 | 0.07 | 0.06 | -0.01 | buy |
| BlackRock, Inc. | 5,281,375 | 5,722,045 | +440,670 | 0.00 | 0.00 | -0.00 | buy |
| FMR LLC | 42,274 | 442,992 | +400,718 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 3,707,445 | 4,085,580 | +378,135 | 0.06 | 0.05 | -0.01 | buy |
| HSBC HOLDINGS PLC | 257,615 | 625,140 | +367,525 | 0.00 | 0.00 | +0.00 | buy |
| Principia Wealth Advisory, LLC | 270,382 | 533,778 | +263,396 | 1.89 | 2.35 | +0.46 | buy |
| WELLS FARGO & COMPANY/MN | 34,792 | 271,611 | +236,819 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 213,382 | 357,442 | +144,060 | 0.00 | 0.00 | +0.00 | buy |
| Blue Owl Capital Holdings LP | 667,594 | 797,594 | +130,000 | 1.15 | 1.39 | +0.25 | buy |
| MORGAN STANLEY | 745,395 | 864,111 | +118,716 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 648,030 | 750,212 | +102,182 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 1,491,667 | 1,593,211 | +101,544 | 0.00 | 0.00 | -0.00 | buy |
| Artia Global Partners LP | 216,700 | 316,700 | +100,000 | 0.65 | 0.50 | -0.15 | buy |
| Simplify Asset Management Inc. | 0 | 88,155 | +88,155 | 0.00 | 0.02 | +0.02 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 123,769 | 206,605 | +82,836 | 0.02 | 0.02 | +0.00 | buy |
| Patient Square Capital LP | 1,410,331 | 1,481,977 | +71,646 | 3.93 | 3.32 | -0.61 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 177,316 | 233,231 | +55,915 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,538,902 | 1,593,030 | +54,128 | 0.00 | 0.00 | -0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 95,149 | 148,049 | +52,900 | 0.00 | 0.00 | +0.00 | buy |
| CANADA PENSION PLAN INVESTMENT BOARD | 50,700 | 97,200 | +46,500 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 43,740 | +43,740 | 0.00 | 0.01 | +0.01 | buy |
| AMERICAN CENTURY COMPANIES INC | 0 | 42,860 | +42,860 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 48,614 | 90,879 | +42,265 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 52,038 | 94,250 | +42,212 | 0.00 | 0.00 | +0.00 | buy |
| Dynamic Technology Lab Private Ltd | 32,178 | 73,310 | +41,132 | 0.04 | 0.06 | +0.02 | buy |
| Waverly Advisors, LLC | 0 | 36,632 | +36,632 | 0.00 | 0.00 | +0.00 | buy |
| EntryPoint Capital, LLC | 0 | 34,324 | +34,324 | 0.00 | 0.09 | +0.09 | buy |
| Walleye Capital LLC | 0 | 33,206 | +33,206 | 0.00 | 0.00 | +0.00 | buy |
| Jain Global LLC | 0 | 31,380 | +31,380 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 3,803,227 | 3,834,368 | +31,141 | 0.00 | 0.00 | -0.00 | buy |
| OXFORD ASSET MANAGEMENT LLP | 0 | 28,357 | +28,357 | 0.00 | 0.07 | +0.07 | buy |
| Invesco Ltd. | 15,657 | 42,948 | +27,291 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 0 | 25,260 | +25,260 | 0.00 | 0.00 | +0.00 | buy |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 6,783,091 | 6,804,091 | +21,000 | 1.87 | 1.49 | -0.38 | buy |
| Creative Planning | 187 | 20,895 | +20,708 | 0.00 | 0.00 | +0.00 | buy |
| Virtus Investment Advisers, LLC | 0 | 20,674 | +20,674 | 0.00 | 0.03 | +0.03 | buy |
| MYDA Advisors LLC | 160,000 | 180,000 | +20,000 | 0.34 | 0.35 | +0.01 | buy |
| SCOTIA CAPITAL INC. | 12,421 | 31,589 | +19,168 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 0 | 14,509 | +14,509 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 0 | 14,505 | +14,505 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 6,514 | 20,114 | +13,600 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 23,105 | 36,353 | +13,248 | 0.00 | 0.00 | +0.00 | buy |
| Swiss National Bank | 100,000 | 112,400 | +12,400 | 0.00 | 0.00 | -0.00 | buy |
| FRANKLIN RESOURCES INC | 4,137,567 | 4,149,861 | +12,294 | 0.01 | 0.01 | -0.00 | buy |
| WOLVERINE TRADING, LLC | 0 | 11,959 | +11,959 | 0.00 | 0.00 | +0.00 | buy |
| Quantinno Capital Management LP | 0 | 11,526 | +11,526 | 0.00 | 0.00 | +0.00 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 0 | 11,450 | +11,450 | 0.00 | 0.00 | +0.00 | buy |
| Greenwich Wealth Management LLC | 0 | 10,050 | +10,050 | 0.00 | 0.00 | +0.00 | buy |
| DELTEC ASSET MANAGEMENT LLC | 20,300 | 30,300 | +10,000 | 0.03 | 0.04 | +0.01 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 13,895 | 22,571 | +8,676 | 0.00 | 0.00 | +0.00 | buy |
| Cyndeo Wealth Partners, LLC | 16,990 | 25,250 | +8,260 | 0.01 | 0.01 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 43,790 | 50,890 | +7,100 | 0.00 | 0.00 | -0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 90,349 | 96,811 | +6,462 | 0.00 | 0.00 | -0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 110,550 | 116,099 | +5,549 | 0.00 | 0.00 | -0.00 | buy |
| One68 Global Capital, LLC | 25,800 | 30,800 | +5,000 | 0.10 | 0.08 | -0.02 | buy |
| Laurion Capital Management LP | 205,578 | 210,006 | +4,428 | 0.10 | 0.09 | -0.01 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 86,809 | 88,780 | +1,971 | 0.00 | 0.00 | -0.00 | buy |
| Arizona State Retirement System | 14,723 | 16,600 | +1,877 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 37,022 | 38,660 | +1,638 | 0.00 | 0.00 | -0.00 | buy |
| GAMMA Investing LLC | 313 | 1,891 | +1,578 | 0.00 | 0.00 | +0.00 | buy |
| SIGNATUREFD, LLC | 0 | 1,345 | +1,345 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 0 | 1,149 | +1,149 | 0.00 | 0.00 | +0.00 | buy |
| TOTH FINANCIAL ADVISORY CORP | 1,001 | 2,001 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 1,259 | 2,256 | +997 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 35 | 761 | +726 | 0.00 | 0.00 | +0.00 | buy |
| QUADRANT CAPITAL GROUP LLC | 0 | 583 | +583 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 10,148 | 10,723 | +575 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 0 | 320 | +320 | 0.00 | 0.00 | +0.00 | buy |
| GF FUND MANAGEMENT CO. LTD. | 1,433 | 1,747 | +314 | 0.00 | 0.00 | -0.00 | buy |
| MassMutual Private Wealth & Trust, FSB | 65 | 345 | +280 | 0.00 | 0.00 | +0.00 | buy |
| HighTower Advisors, LLC | 32,291 | 32,567 | +276 | 0.00 | 0.00 | -0.00 | buy |
| Versant Capital Management, Inc | 492 | 741 | +249 | 0.00 | 0.00 | -0.00 | buy |
| TEACHER RETIREMENT SYSTEM OF TEXAS | 15,192 | 15,338 | +146 | 0.00 | 0.00 | -0.00 | buy |
| Parallel Advisors, LLC | 0 | 121 | +121 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 105 | +105 | 0.00 | 0.00 | +0.00 | buy |
| Parkside Financial Bank & Trust | 0 | 70 | +70 | 0.00 | 0.00 | +0.00 | buy |
| Larson Financial Group LLC | 0 | 59 | +59 | 0.00 | 0.00 | +0.00 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 21 | +21 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 100 | 120 | +20 | 0.00 | 0.00 | -0.00 | buy |
| SBI Securities Co., Ltd. | 14 | 20 | +6 | 0.00 | 0.00 | +0.00 | buy |
| WOODSTOCK CORP | 71,480 | 71,480 | 0 | 0.05 | 0.04 | -0.01 | hold |
| Ameritas Investment Partners, Inc. | 6,838 | 6,838 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PERCEPTIVE ADVISORS LLC | 1,537,274 | 1,537,274 | 0 | 0.32 | 0.30 | -0.02 | hold |
| JANUS HENDERSON GROUP PLC | 26,700 | 26,700 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RA CAPITAL MANAGEMENT, L.P. | 3,181,818 | 3,181,818 | 0 | 0.32 | 0.29 | -0.03 | hold |
| Alyeska Investment Group, L.P. | 351,348 | 351,348 | 0 | 0.01 | 0.01 | -0.00 | hold |
| DekaBank Deutsche Girozentrale | 35,000 | 35,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Daiwa Securities Group Inc. | 144 | 144 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Skandinaviska Enskilda Banken AB (publ) | 71,515 | 71,515 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Essex Woodlands Management, Inc. | 1,169,857 | 1,169,857 | 0 | 2.01 | 1.83 | -0.18 | hold |
| Cormorant Asset Management, LP | 8,325,000 | 8,325,000 | 0 | 3.41 | 3.42 | +0.01 | hold |
| IFP Advisors, Inc | 0 | 0 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Aberdeen Group plc | 230,745 | 230,745 | 0 | 0.00 | 0.00 | -0.00 | hold |
| KLP KAPITALFORVALTNING AS | 7,900 | 7,900 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Truvestments Capital LLC | 258 | 258 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Cedar Mountain Advisors, LLC | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| 5AM Venture Management, LLC | 1,050,000 | 1,050,000 | 0 | 1.87 | 2.15 | +0.29 | hold |
| TCG Crossover Management, LLC | 3,572,335 | 3,572,335 | 0 | 2.60 | 2.64 | +0.04 | hold |
| Washington Trust Advisors, Inc. | 264 | 264 | 0 | 0.00 | 0.00 | -0.00 | hold |