| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BRAIDWELL LP | 615,531 | 1,655,690 | +1,040,159 | 0.42 | 0.62 | +0.20 | buy |
| PRIMECAP MANAGEMENT CO/CA/ | 8,984,432 | 9,761,012 | +776,580 | 0.16 | 0.09 | -0.07 | buy |
| STATE STREET CORP | 3,200,913 | 3,683,715 | +482,802 | 0.00 | 0.00 | -0.00 | buy |
| Hudson Bay Capital Management LP | 0 | 460,890 | +460,890 | 0.00 | 0.03 | +0.03 | buy |
| Nantahala Capital Management, LLC | 0 | 456,741 | +456,741 | 0.00 | 0.40 | +0.40 | buy |
| BVF INC/IL | 2,288,760 | 2,740,141 | +451,381 | 1.78 | 1.19 | -0.59 | buy |
| BANK OF AMERICA CORP /DE/ | 33,507 | 482,691 | +449,184 | 0.00 | 0.00 | +0.00 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 519,976 | 904,485 | +384,509 | 0.04 | 0.04 | -0.00 | buy |
| GOLDMAN SACHS GROUP INC | 382,646 | 726,734 | +344,088 | 0.00 | 0.00 | -0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 30,204 | 290,328 | +260,124 | 0.00 | 0.02 | +0.01 | buy |
| DIMENSIONAL FUND ADVISORS LP | 1,501,532 | 1,737,388 | +235,856 | 0.01 | 0.00 | -0.00 | buy |
| Aberdeen Group plc | 175,520 | 377,112 | +201,592 | 0.01 | 0.01 | +0.00 | buy |
| Invesco Ltd. | 454,745 | 656,201 | +201,456 | 0.00 | 0.00 | -0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 166,689 | +166,689 | 0.00 | 0.02 | +0.02 | buy |
| ADAR1 Capital Management, LLC | 234,607 | 398,152 | +163,545 | 1.11 | 0.82 | -0.30 | buy |
| Cubist Systematic Strategies, LLC | 0 | 155,580 | +155,580 | 0.00 | 0.02 | +0.02 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 152,400 | +152,400 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 744,612 | 854,723 | +110,111 | 0.00 | 0.00 | -0.00 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 0 | 101,392 | +101,392 | 0.00 | 0.02 | +0.02 | buy |
| Campbell & CO Investment Adviser LLC | 0 | 77,341 | +77,341 | 0.00 | 0.06 | +0.06 | buy |
| FMR LLC | 4,233 | 76,652 | +72,419 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 59,383 | +59,383 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 40,903 | 99,578 | +58,675 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 0 | 50,473 | +50,473 | 0.00 | 0.01 | +0.01 | buy |
| Trexquant Investment LP | 83,241 | 133,360 | +50,119 | 0.02 | 0.02 | -0.01 | buy |
| Y-Intercept (Hong Kong) Ltd | 0 | 49,605 | +49,605 | 0.00 | 0.04 | +0.04 | buy |
| UBS Group AG | 892,276 | 941,842 | +49,566 | 0.00 | 0.00 | -0.00 | buy |
| Deep Track Capital, LP | 500,000 | 549,439 | +49,439 | 0.43 | 0.19 | -0.24 | buy |
| PUBLIC SECTOR PENSION INVESTMENT BOARD | 174,309 | 221,971 | +47,662 | 0.02 | 0.01 | -0.01 | buy |
| CITIGROUP INC | 117,988 | 165,179 | +47,191 | 0.00 | 0.00 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 41,127 | +41,127 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,634,876 | 1,674,348 | +39,472 | 0.00 | 0.00 | -0.00 | buy |
| XTX Topco Ltd | 18,582 | 54,209 | +35,627 | 0.04 | 0.03 | -0.01 | buy |
| Rafferty Asset Management, LLC | 51,976 | 86,741 | +34,765 | 0.00 | 0.00 | -0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 33,297 | +33,297 | 0.00 | 0.00 | +0.00 | buy |
| WINTON GROUP Ltd | 53,705 | 85,970 | +32,265 | 0.08 | 0.06 | -0.03 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 33,972 | 64,681 | +30,709 | 0.01 | 0.01 | -0.00 | buy |
| TEXAS PERMANENT SCHOOL FUND CORP | 0 | 28,073 | +28,073 | 0.00 | 0.00 | +0.00 | buy |
| Verition Fund Management LLC | 0 | 28,032 | +28,032 | 0.00 | 0.00 | +0.00 | buy |
| Erste Asset Management GmbH | 352,200 | 380,200 | +28,000 | 0.10 | 0.05 | -0.05 | buy |
| AMERICAN CENTURY COMPANIES INC | 114,231 | 139,242 | +25,011 | 0.00 | 0.00 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 16,528 | 37,330 | +20,802 | 0.00 | 0.00 | +0.00 | buy |
| Quinn Opportunity Partners LLC | 0 | 20,000 | +20,000 | 0.00 | 0.01 | +0.01 | buy |
| AMERIPRISE FINANCIAL INC | 292,576 | 308,958 | +16,382 | 0.00 | 0.00 | -0.00 | buy |
| Diversified Trust Co | 0 | 16,200 | +16,200 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 0 | 14,942 | +14,942 | 0.00 | 0.00 | +0.00 | buy |
| Inspire Investing, LLC | 17,489 | 32,402 | +14,913 | 0.04 | 0.04 | -0.00 | buy |
| Creative Planning | 65 | 14,469 | +14,404 | 0.00 | 0.00 | +0.00 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0 | 12,733 | +12,733 | 0.00 | 0.00 | +0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 0 | 12,704 | +12,704 | 0.00 | 0.00 | +0.00 | buy |
| Corient Private Wealth LLC | 0 | 12,473 | +12,473 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 0 | 11,323 | +11,323 | 0.00 | 0.00 | +0.00 | buy |
| INCEPTIONR LLC | 0 | 11,102 | +11,102 | 0.00 | 0.04 | +0.04 | buy |
| PRINCIPAL FINANCIAL GROUP INC | 340,145 | 348,726 | +8,581 | 0.00 | 0.00 | -0.00 | buy |
| Advantage Alpha Capital Partners LP | 13,548 | 21,760 | +8,212 | 0.07 | 0.06 | -0.01 | buy |
| Illinois Municipal Retirement Fund | 33,198 | 41,377 | +8,179 | 0.01 | 0.01 | -0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 297,223 | 305,131 | +7,908 | 0.02 | 0.01 | -0.01 | buy |
| US BANCORP \DE\ | 2,532 | 10,432 | +7,900 | 0.00 | 0.00 | +0.00 | buy |
| PROFUND ADVISORS LLC | 13,416 | 20,294 | +6,878 | 0.01 | 0.01 | -0.00 | buy |
| Capula Management Ltd | 13,120 | 19,856 | +6,736 | 0.00 | 0.00 | -0.00 | buy |
| Virtus Investment Advisers, LLC | 0 | 6,634 | +6,634 | 0.00 | 0.02 | +0.02 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 630,640 | 636,656 | +6,016 | 0.00 | 0.00 | -0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 5,601 | +5,601 | 0.00 | 0.00 | +0.00 | buy |
| AlphaQuest LLC | 0 | 5,305 | +5,305 | 0.00 | 0.01 | +0.01 | buy |
| ROYAL BANK OF CANADA | 5,928 | 10,098 | +4,170 | 0.00 | 0.00 | -0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 40,355 | 44,047 | +3,692 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 36,086 | 39,460 | +3,374 | 0.00 | 0.00 | -0.00 | buy |
| State of Wyoming | 0 | 3,179 | +3,179 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 13,119 | 16,236 | +3,117 | 0.02 | 0.02 | -0.01 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 27,491 | 29,776 | +2,285 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 1,141 | 3,372 | +2,231 | 0.00 | 0.00 | +0.00 | buy |
| EXCHANGE TRADED CONCEPTS, LLC | 7,918 | 9,814 | +1,896 | 0.00 | 0.00 | -0.00 | buy |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS | 14,940 | 16,747 | +1,807 | 0.00 | 0.00 | -0.00 | buy |
| NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 58,126 | 59,326 | +1,200 | 0.00 | 0.00 | -0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 19,631 | 20,677 | +1,046 | 0.00 | 0.00 | -0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 100,373 | 101,407 | +1,034 | 0.00 | 0.00 | -0.00 | buy |
| State of Tennessee, Department of Treasury | 27,992 | 28,937 | +945 | 0.00 | 0.00 | -0.00 | buy |
| Mitsubishi UFJ Asset Management Co., Ltd. | 10,657 | 11,598 | +941 | 0.00 | 0.00 | -0.00 | buy |
| Farther Finance Advisors, LLC | 5 | 923 | +918 | 0.00 | 0.00 | +0.00 | buy |
| Brooklyn Investment Group | 35 | 879 | +844 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 121,063 | 121,825 | +762 | 0.00 | 0.00 | -0.00 | buy |
| KBC Group NV | 3,936 | 4,570 | +634 | 0.00 | 0.00 | -0.00 | buy |
| Versant Capital Management, Inc | 680 | 1,294 | +614 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF MONTREAL /CAN/ | 10,408 | 10,828 | +420 | 0.00 | 0.00 | -0.00 | buy |
| EverSource Wealth Advisors, LLC | 2 | 373 | +371 | 0.00 | 0.00 | +0.00 | buy |
| FIFTH THIRD BANCORP | 479 | 844 | +365 | 0.00 | 0.00 | -0.00 | buy |
| Linden Thomas Advisory Services, LLC | 42,877 | 43,227 | +350 | 0.12 | 0.06 | -0.07 | buy |
| GF FUND MANAGEMENT CO. LTD. | 1,469 | 1,791 | +322 | 0.00 | 0.00 | -0.00 | buy |
| Caitong International Asset Management Co., Ltd | 0 | 304 | +304 | 0.00 | 0.00 | +0.00 | buy |
| UMB Bank, n.a. | 137 | 376 | +239 | 0.00 | 0.00 | +0.00 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 220 | +220 | 0.00 | 0.00 | +0.00 | buy |
| High Note Wealth, LLC | 0 | 208 | +208 | 0.00 | 0.00 | +0.00 | buy |
| COMERICA BANK | 20,527 | 20,727 | +200 | 0.00 | 0.00 | -0.00 | buy |
| True Wealth Design, LLC | 0 | 158 | +158 | 0.00 | 0.00 | +0.00 | buy |
| Aster Capital Management (DIFC) Ltd | 0 | 114 | +114 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 2,289 | 2,329 | +40 | 0.00 | 0.00 | -0.00 | buy |
| EP Wealth Advisors, LLC | 13,000 | 13,039 | +39 | 0.00 | 0.00 | -0.00 | buy |
| Stephens Consulting, LLC | 0 | 35 | +35 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 2,332 | 2,358 | +26 | 0.00 | 0.00 | -0.00 | buy |
| HANTZ FINANCIAL SERVICES, INC. | 0 | 11 | +11 | 0.00 | 0.00 | 0.00 | buy |