| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| GEODE CAPITAL MANAGEMENT, LLC | 885,966 | 1,016,004 | +130,038 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 41,258 | 87,710 | +46,452 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 286,310 | 332,639 | +46,329 | 0.00 | 0.00 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 28,713 | 58,041 | +29,328 | 0.00 | 0.00 | -0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 16,560 | +16,560 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 15,283 | +15,283 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 39,785 | 52,736 | +12,951 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 0 | 10,739 | +10,739 | 0.00 | 0.00 | +0.00 | buy |
| Sassicaia Capital Advisers LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0 | 6,000 | +6,000 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 27,770 | 29,018 | +1,248 | 0.00 | 0.00 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 363 | 1,317 | +954 | 0.00 | 0.00 | 0.00 | buy |
| EverSource Wealth Advisors, LLC | 119 | 343 | +224 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 4,269 | 4,272 | +3 | 0.00 | 0.00 | -0.00 | buy |
| Ameritas Investment Partners, Inc. | 4,741 | 4,741 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,507 | 3,507 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 33,120 | 33,120 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PERCEPTIVE ADVISORS LLC | 12,757,562 | 12,757,562 | 0 | 0.07 | 0.06 | -0.02 | hold |
| Sterling Capital Management LLC | 88 | 88 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BOOTHBAY FUND MANAGEMENT, LLC | 233,989 | 233,989 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ikarian Capital, LLC | 1,058,148 | 1,058,148 | 0 | 0.06 | 0.04 | -0.02 | hold |
| ADAR1 Capital Management, LLC | 533,200 | 533,200 | 0 | 0.02 | 0.01 | -0.01 | hold |
| PRICE T ROWE ASSOCIATES INC /MD/ | 17,541 | 17,541 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 154,800 | 154,800 | 0 | 0.00 | 0.00 | -0.00 | hold |
| JONES FINANCIAL COMPANIES LLLP | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 111,609 | 111,609 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Wilmington Savings Fund Society, FSB | 1,025 | 1,025 | 0 | 0.00 | 0.00 | -0.00 | hold |
| COMERICA BANK | 1,159 | 1,159 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Invesco Ltd. | 23,626 | 23,626 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 1,674 | 1,674 | 0 | 0.00 | 0.00 | 0.00 | hold |
| STATE STREET CORP | 488,720 | 488,720 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NISA INVESTMENT ADVISORS, LLC | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Corebridge Financial, Inc. | 24,061 | 23,709 | -352 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 244,920 | 242,546 | -2,374 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 38,102 | 35,177 | -2,925 | 0.00 | 0.00 | -0.00 | sell |
| ProShare Advisors LLC | 13,631 | 10,477 | -3,154 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 75,966 | 71,585 | -4,381 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 5,371 | 0 | -5,371 | 0.00 | 0.00 | -0.00 | sell |
| Abel Hall, LLC | 17,647 | 12,214 | -5,433 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 209,997 | 193,145 | -16,852 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 31,907 | 14,620 | -17,287 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 385,500 | 364,478 | -21,022 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 1,787,422 | 1,765,585 | -21,837 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 75,254 | 50,038 | -25,216 | 0.00 | 0.00 | -0.00 | sell |
| FMR LLC | 99,791 | 58,213 | -41,578 | 0.00 | 0.00 | -0.00 | sell |
| Virtu Financial LLC | 42,069 | 0 | -42,069 | 0.00 | 0.00 | -0.00 | sell |
| SEI INVESTMENTS CO | 84,075 | 30,067 | -54,008 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF MONTREAL /CAN/ | 54,130 | 0 | -54,130 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 3,109,798 | 3,018,986 | -90,812 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 555,508 | 370,194 | -185,314 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 342,159 | 0 | -342,159 | 0.00 | 0.00 | -0.00 | sell |
| Samsara BioCapital, LLC | 1,965,689 | 1,390,130 | -575,559 | 0.06 | 0.03 | -0.02 | sell |