| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Sio Capital Management, LLC | 0 | 1,715,394 | +1,715,394 | 0.00 | 1.52 | +1.52 | buy |
| ADAR1 Capital Management, LLC | 35,223 | 1,136,799 | +1,101,576 | 0.02 | 0.45 | +0.44 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 0 | 1,043,478 | +1,043,478 | 0.00 | 0.01 | +0.01 | buy |
| JANUS HENDERSON GROUP PLC | 4,231,331 | 5,141,616 | +910,285 | 0.01 | 0.01 | +0.00 | buy |
| Integral Health Asset Management, LLC | 1,400,000 | 2,250,000 | +850,000 | 0.44 | 0.61 | +0.16 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 444,444 | 1,259,427 | +814,983 | 0.01 | 0.05 | +0.03 | buy |
| Maven Securities LTD | 0 | 754,626 | +754,626 | 0.00 | 0.51 | +0.51 | buy |
| Velan Capital Investment Management LP | 2,139,000 | 2,834,652 | +695,652 | 8.74 | 8.79 | +0.05 | buy |
| SPHERA FUNDS MANAGEMENT LTD. | 0 | 650,000 | +650,000 | 0.00 | 0.72 | +0.72 | buy |
| 5AM Venture Management, LLC | 800,000 | 1,369,782 | +569,782 | 1.27 | 2.30 | +1.02 | buy |
| VANGUARD GROUP INC | 1,904,156 | 2,391,903 | +487,747 | 0.00 | 0.00 | +0.00 | buy |
| Burkehill Global Management, LP | 0 | 450,000 | +450,000 | 0.00 | 0.16 | +0.16 | buy |
| BAKER BROS. ADVISORS LP | 536,832 | 971,614 | +434,782 | 0.02 | 0.03 | +0.01 | buy |
| CITADEL ADVISORS LLC | 502,454 | 901,541 | +399,087 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 843,074 | 1,215,537 | +372,463 | 0.00 | 0.00 | +0.00 | buy |
| Alyeska Investment Group, L.P. | 0 | 350,000 | +350,000 | 0.00 | 0.01 | +0.01 | buy |
| BANK OF AMERICA CORP /DE/ | 180,475 | 495,904 | +315,429 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 285,586 | 584,528 | +298,942 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 350,091 | 570,878 | +220,787 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 2,229,368 | 2,408,868 | +179,500 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 47,708 | 227,157 | +179,449 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 156,135 | +156,135 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 0 | 153,985 | +153,985 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 0 | 145,876 | +145,876 | 0.00 | 0.00 | +0.00 | buy |
| Monashee Investment Management LLC | 0 | 125,000 | +125,000 | 0.00 | 0.38 | +0.38 | buy |
| XTX Topco Ltd | 0 | 115,363 | +115,363 | 0.00 | 0.02 | +0.02 | buy |
| Qube Research & Technologies Ltd | 0 | 114,331 | +114,331 | 0.00 | 0.00 | +0.00 | buy |
| Informed Momentum Co LLC | 0 | 103,611 | +103,611 | 0.00 | 0.06 | +0.06 | buy |
| Virtu Financial LLC | 0 | 68,956 | +68,956 | 0.00 | 0.01 | +0.01 | buy |
| MILLENNIUM MANAGEMENT LLC | 688,256 | 753,302 | +65,046 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 0 | 63,492 | +63,492 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 0 | 63,079 | +63,079 | 0.00 | 0.00 | +0.00 | buy |
| Marex Group plc | 22,250 | 85,250 | +63,000 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 758,719 | 817,196 | +58,477 | 0.00 | 0.00 | +0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 0 | 43,796 | +43,796 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 0 | 42,389 | +42,389 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 36,260 | +36,260 | 0.00 | 0.00 | +0.00 | buy |
| Longaeva Partners L.P. | 0 | 33,857 | +33,857 | 0.00 | 0.02 | +0.02 | buy |
| Point72 Asset Management, L.P. | 0 | 28,107 | +28,107 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 81,203 | 106,846 | +25,643 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 0 | 25,096 | +25,096 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 21,886 | +21,886 | 0.00 | 0.00 | +0.00 | buy |
| Campbell & CO Investment Adviser LLC | 0 | 20,551 | +20,551 | 0.00 | 0.01 | +0.01 | buy |
| Scientech Research LLC | 0 | 17,215 | +17,215 | 0.00 | 0.06 | +0.06 | buy |
| OPPENHEIMER & CO INC | 206,973 | 223,767 | +16,794 | 0.01 | 0.02 | +0.01 | buy |
| GROUP ONE TRADING LLC | 2,900 | 18,400 | +15,500 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 24,765 | 39,802 | +15,037 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 14,681 | +14,681 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 378 | 14,700 | +14,322 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 19,558 | 32,662 | +13,104 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0 | 11,084 | +11,084 | 0.00 | 0.00 | +0.00 | buy |
| AXQ CAPITAL, LP | 0 | 10,815 | +10,815 | 0.00 | 0.01 | +0.01 | buy |
| Persistent Asset Partners Ltd | 0 | 10,733 | +10,733 | 0.00 | 0.03 | +0.03 | buy |
| Almanack Investment Partners, LLC. | 13,494 | 23,782 | +10,288 | 0.01 | 0.02 | +0.01 | buy |
| BARCLAYS PLC | 45,520 | 55,057 | +9,537 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 17,346 | 24,184 | +6,838 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 95,774 | 102,499 | +6,725 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 234,360 | 240,756 | +6,396 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 0 | 4,399 | +4,399 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 16,353 | 20,736 | +4,383 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 61,554 | 64,158 | +2,604 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 14,852 | 16,354 | +1,502 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 10,000 | 11,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| Assenagon Asset Management S.A. | 307,422 | 308,334 | +912 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 0 | 883 | +883 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 12,385 | 12,692 | +307 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 2,017 | 2,169 | +152 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 1,103 | 1,108 | +5 | 0.00 | 0.00 | +0.00 | buy |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0 | 2 | +2 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 3,298 | 3,298 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 44,830 | 44,830 | 0 | 0.00 | 0.01 | +0.00 | hold |
| Blackstone Inc. | 1,909,662 | 1,909,662 | 0 | 0.04 | 0.04 | +0.01 | hold |
| Russell Investments Group, Ltd. | 2,676 | 2,676 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SUPERSTRING CAPITAL MANAGEMENT LP | 360,000 | 360,000 | 0 | 1.54 | 1.03 | -0.52 | hold |
| Police & Firemen's Retirement System of New Jersey | 9,921 | 9,921 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ACORN CAPITAL ADVISORS, LLC | 1,752,115 | 1,752,115 | 0 | 3.87 | 3.16 | -0.70 | hold |
| Legal & General Group Plc | 2,937 | 2,937 | 0 | 0.00 | 0.00 | +0.00 | hold |
| TRUIST FINANCIAL CORP | 40,000 | 40,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SBI Securities Co., Ltd. | 105 | 103 | -2 | 0.00 | 0.00 | +0.00 | sell |
| Arax Advisory Partners | 48 | 0 | -48 | 0.00 | 0.00 | -0.00 | sell |
| Farther Finance Advisors, LLC | 55 | 0 | -55 | 0.00 | 0.00 | -0.00 | sell |
| Sterling Capital Management LLC | 2,229 | 2,032 | -197 | 0.00 | 0.00 | +0.00 | sell |
| Advisory Services Network, LLC | 1,000 | 0 | -1,000 | 0.00 | 0.00 | -0.00 | sell |
| INTECH INVESTMENT MANAGEMENT LLC | 15,900 | 13,821 | -2,079 | 0.00 | 0.00 | +0.00 | sell |
| Bank of New York Mellon Corp | 96,993 | 93,522 | -3,471 | 0.00 | 0.00 | +0.00 | sell |
| Tower Research Capital LLC (TRC) | 5,587 | 2,073 | -3,514 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 19,700 | 15,000 | -4,700 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 34,137 | 26,865 | -7,272 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 25,169 | 17,514 | -7,655 | 0.00 | 0.00 | -0.00 | sell |
| BAILARD, INC. | 36,669 | 24,417 | -12,252 | 0.00 | 0.00 | -0.00 | sell |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 15,545 | 0 | -15,545 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 17,890 | 0 | -17,890 | 0.00 | 0.00 | -0.00 | sell |
| PRELUDE CAPITAL MANAGEMENT, LLC | 21,516 | 0 | -21,516 | 0.01 | 0.00 | -0.01 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 50,455 | 7,617 | -42,838 | 0.00 | 0.00 | -0.00 | sell |
| CIBC WORLD MARKET INC. | 274,994 | 228,895 | -46,099 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 314,300 | 266,807 | -47,493 | 0.00 | 0.00 | +0.00 | sell |
| GSA CAPITAL PARTNERS LLP | 101,488 | 52,332 | -49,156 | 0.04 | 0.02 | -0.01 | sell |
| Catalio Capital Management, LP | 1,500,793 | 1,446,254 | -54,539 | 1.21 | 1.36 | +0.16 | sell |
| J. Goldman & Co LP | 100,350 | 0 | -100,350 | 0.02 | 0.00 | -0.02 | sell |