| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| DEERFIELD MANAGEMENT COMPANY, L.P. | 30,606,974 | 35,606,974 | +5,000,000 | 1.49 | 1.89 | +0.40 | buy |
| Blue Owl Capital Holdings LP | 6,823,690 | 7,120,007 | +296,317 | 8.02 | 8.61 | +0.59 | buy |
| BlackRock, Inc. | 3,681,603 | 3,752,200 | +70,597 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 5,206,364 | 3,625,278 | -1,581,086 | 0.01 | 0.01 | -0.00 | sell |
| AIGH Capital Management LLC | 2,000,000 | 3,000,000 | +1,000,000 | 2.25 | 2.76 | +0.51 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 535,464 | 2,934,399 | +2,398,935 | 0.01 | 0.10 | +0.08 | buy |
| DAFNA Capital Management LLC | 939,164 | 2,029,164 | +1,090,000 | 0.83 | 2.08 | +1.25 | buy |
| GOLDMAN SACHS GROUP INC | 1,347,215 | 1,561,585 | +214,370 | 0.00 | 0.00 | +0.00 | buy |
| RTW INVESTMENTS, LP | 3,125,000 | 1,500,000 | -1,625,000 | 0.12 | 0.07 | -0.05 | sell |
| Deep Track Capital, LP | 0 | 1,500,000 | +1,500,000 | 0.00 | 0.14 | +0.14 | buy |
| Woodline Partners LP | 800,850 | 1,400,850 | +600,000 | 0.01 | 0.02 | +0.01 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,093,323 | 1,108,761 | +15,438 | 0.00 | 0.00 | +0.00 | buy |
| Soleus Capital Management, L.P. | 0 | 1,066,960 | +1,066,960 | 0.00 | 0.19 | +0.19 | buy |
| Point72 Asset Management, L.P. | 1,461,028 | 1,047,385 | -413,643 | 0.01 | 0.01 | -0.00 | sell |
| Blue Owl Capital Holdings LP | 0 | 975,700 | +975,700 | 0.00 | 0.51 | +0.51 | buy |
| MARSHALL WACE, LLP | 0 | 933,464 | +933,464 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 911,925 | 911,326 | -599 | 0.00 | 0.00 | +0.00 | sell |
| Qube Research & Technologies Ltd | 0 | 847,644 | +847,644 | 0.00 | 0.01 | +0.01 | buy |
| AQR CAPITAL MANAGEMENT LLC | 502,251 | 817,517 | +315,266 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 327,494 | 798,462 | +470,968 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 297,266 | 739,942 | +442,676 | 0.00 | 0.01 | +0.00 | buy |
| Nuveen, LLC | 105,182 | 674,915 | +569,733 | 0.00 | 0.00 | +0.00 | buy |
| Caption Management, LLC | 415,294 | 635,024 | +219,730 | 0.07 | 0.14 | +0.07 | buy |
| Alyeska Investment Group, L.P. | 927,821 | 617,211 | -310,610 | 0.01 | 0.01 | -0.00 | sell |
| D. E. Shaw & Co., Inc. | 437,399 | 575,624 | +138,225 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 678,942 | 554,007 | -124,935 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 1,366,750 | 519,132 | -847,618 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 295,183 | 475,612 | +180,429 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 0 | 420,813 | +420,813 | 0.00 | 0.00 | +0.00 | buy |
| SummitTX Capital, L.P. | 0 | 379,765 | +379,765 | 0.00 | 0.05 | +0.05 | buy |
| NORTHERN TRUST CORP | 356,775 | 376,503 | +19,728 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 24,864 | 331,818 | +306,954 | 0.00 | 0.00 | +0.00 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 0 | 300,000 | +300,000 | 0.00 | 0.00 | +0.00 | buy |
| Burkehill Global Management, LP | 0 | 300,000 | +300,000 | 0.00 | 0.07 | +0.07 | buy |
| Jump Financial, LLC | 96,074 | 299,700 | +203,626 | 0.00 | 0.02 | +0.02 | buy |
| Hudson Bay Capital Management LP | 0 | 292,250 | +292,250 | 0.00 | 0.01 | +0.01 | buy |
| Cerity Partners LLC | 234,737 | 247,912 | +13,175 | 0.00 | 0.00 | +0.00 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | 169,144 | +169,144 | 0.00 | 0.00 | +0.00 | buy |
| DIADEMA PARTNERS LP | 0 | 166,637 | +166,637 | 0.00 | 0.31 | +0.31 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 162,113 | 145,342 | -16,771 | 0.00 | 0.00 | +0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 252,783 | 140,060 | -112,723 | 0.00 | 0.00 | -0.00 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 0 | 136,530 | +136,530 | 0.00 | 0.00 | +0.00 | buy |
| SEVEN GRAND MANAGERS, LLC | 0 | 125,000 | +125,000 | 0.00 | 0.04 | +0.04 | buy |
| HRT FINANCIAL LP | 0 | 121,885 | +121,885 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 49,150 | 114,038 | +64,888 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 115,928 | 107,331 | -8,597 | 0.00 | 0.00 | +0.00 | sell |
| DEUTSCHE BANK AG\ | 34,390 | 93,132 | +58,742 | 0.00 | 0.00 | +0.00 | buy |
| Marex Group plc | 312,000 | 82,000 | -230,000 | 0.01 | 0.00 | -0.01 | sell |
| AMERICAN CENTURY COMPANIES INC | 75,541 | 77,636 | +2,095 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 74,530 | 74,530 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Connor, Clark & Lunn Investment Management Ltd. | 21,070 | 69,087 | +48,017 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 35,618 | 65,037 | +29,419 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 32,631 | 64,126 | +31,495 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 12,880 | 63,570 | +50,690 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 63,565 | 62,685 | -880 | 0.00 | 0.00 | +0.00 | sell |
| FEDERATED HERMES, INC. | 358,907 | 61,350 | -297,557 | 0.00 | 0.00 | -0.00 | sell |
| CANADA PENSION PLAN INVESTMENT BOARD | 94,000 | 59,700 | -34,300 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 64,670 | 59,481 | -5,189 | 0.00 | 0.00 | -0.00 | sell |
| CIBC WORLD MARKET INC. | 0 | 53,000 | +53,000 | 0.00 | 0.00 | +0.00 | buy |
| AXQ CAPITAL, LP | 17,655 | 52,973 | +35,318 | 0.02 | 0.03 | +0.02 | buy |
| ADAR1 Capital Management, LLC | 185,689 | 52,745 | -132,944 | 0.05 | 0.01 | -0.04 | sell |
| Virtu Financial LLC | 0 | 51,791 | +51,791 | 0.00 | 0.01 | +0.01 | buy |
| EntryPoint Capital, LLC | 53,321 | 44,479 | -8,842 | 0.08 | 0.06 | -0.02 | sell |
| INCEPTIONR LLC | 0 | 44,006 | +44,006 | 0.00 | 0.05 | +0.05 | buy |
| Persistent Asset Partners Ltd | 0 | 42,124 | +42,124 | 0.00 | 0.07 | +0.07 | buy |
| Next Level Private LLC | 41,700 | 41,700 | 0 | 0.04 | 0.04 | +0.00 | hold |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 111,216 | 41,216 | -70,000 | 0.01 | 0.00 | -0.01 | sell |
| HighTower Advisors, LLC | 0 | 38,465 | +38,465 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 61,759 | 38,090 | -23,669 | 0.00 | 0.00 | +0.00 | sell |
| CITIGROUP INC | 6,488 | 36,107 | +29,619 | 0.00 | 0.00 | +0.00 | buy |
| JOURNEY STRATEGIC WEALTH LLC | 35,836 | 35,883 | +47 | 0.00 | 0.00 | +0.00 | buy |
| Ethic Inc. | 68,102 | 35,451 | -32,651 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 29,008 | 34,768 | +5,760 | 0.00 | 0.00 | +0.00 | buy |
| Graham Capital Management, L.P. | 42,255 | 34,438 | -7,817 | 0.01 | 0.01 | -0.00 | sell |
| J. Goldman & Co LP | 40,500 | 33,756 | -6,744 | 0.01 | 0.01 | +0.00 | sell |
| Velan Capital Investment Management LP | 33,000 | 33,000 | 0 | 0.07 | 0.09 | +0.02 | hold |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 15,614 | 32,799 | +17,185 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 0 | 32,793 | +32,793 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 0 | 31,645 | +31,645 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 1,188 | 31,347 | +30,159 | 0.00 | 0.03 | +0.02 | buy |
| XTX Topco Ltd | 118,938 | 30,884 | -88,054 | 0.01 | 0.00 | -0.01 | sell |
| Fi3 FINANCIAL ADVISORS, LLC | 29,322 | 29,493 | +171 | 0.03 | 0.04 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 0 | 28,796 | +28,796 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 13,597 | 26,668 | +13,071 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 344,246 | 26,445 | -317,801 | 0.01 | 0.00 | -0.01 | sell |
| COMMONWEALTH EQUITY SERVICES, LLC | 22,848 | 24,782 | +1,934 | 0.00 | 0.00 | +0.00 | buy |
| MIRABELLA FINANCIAL SERVICES LLP | 0 | 24,565 | +24,565 | 0.00 | 0.01 | +0.01 | buy |
| Dynamic Technology Lab Private Ltd | 0 | 24,009 | +24,009 | 0.00 | 0.02 | +0.02 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 22,547 | 23,091 | +544 | 0.00 | 0.00 | +0.00 | buy |
| Headlands Technologies LLC | 0 | 22,925 | +22,925 | 0.00 | 0.01 | +0.01 | buy |
| STRS OHIO | 7,900 | 21,700 | +13,800 | 0.00 | 0.00 | +0.00 | buy |
| FRED ALGER MANAGEMENT, LLC | 0 | 21,267 | +21,267 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 56,897 | 20,228 | -36,669 | 0.00 | 0.00 | -0.00 | sell |
| Walleye Trading LLC | 25,000 | 20,000 | -5,000 | 0.00 | 0.00 | +0.00 | sell |
| Invesco Ltd. | 18,401 | 19,647 | +1,246 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 13,947 | 19,270 | +5,323 | 0.00 | 0.01 | +0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 0 | 18,022 | +18,022 | 0.00 | 0.00 | +0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 0 | 17,084 | +17,084 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 78,470 | 16,373 | -62,097 | 0.00 | 0.00 | -0.00 | sell |
| SEI INVESTMENTS CO | 10,573 | 16,336 | +5,763 | 0.00 | 0.00 | +0.00 | buy |