| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| DEERFIELD MANAGEMENT COMPANY, L.P. | 35,606,974 | 35,606,974 | 0 | 1.89 | 1.13 | -0.76 | hold |
| Blue Owl Capital Holdings LP | 7,120,007 | 9,163,157 | +2,043,150 | 8.61 | 4.25 | -4.36 | buy |
| BlackRock, Inc. | 3,752,200 | 5,678,035 | +1,925,835 | 0.00 | 0.00 | -0.00 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 2,934,399 | 3,163,423 | +229,024 | 0.10 | 0.06 | -0.04 | buy |
| RTW INVESTMENTS, LP | 1,500,000 | 2,565,999 | +1,065,999 | 0.07 | 0.07 | -0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 817,517 | 2,371,414 | +1,553,897 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 933,464 | 2,012,458 | +1,078,994 | 0.00 | 0.01 | +0.00 | buy |
| DAFNA Capital Management LLC | 2,029,164 | 2,008,164 | -21,000 | 2.08 | 1.17 | -0.91 | sell |
| GOLDMAN SACHS GROUP INC | 1,561,585 | 1,752,910 | +191,325 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,108,761 | 1,679,003 | +570,242 | 0.00 | 0.00 | -0.00 | buy |
| Qube Research & Technologies Ltd | 847,644 | 1,641,042 | +793,398 | 0.01 | 0.01 | +0.00 | buy |
| CITADEL ADVISORS LLC | 519,132 | 1,456,825 | +937,693 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 911,326 | 1,411,804 | +500,478 | 0.00 | 0.00 | -0.00 | buy |
| Woodline Partners LP | 1,400,850 | 1,400,850 | 0 | 0.02 | 0.01 | -0.01 | hold |
| MILLENNIUM MANAGEMENT LLC | 3,625,278 | 1,333,037 | -2,292,241 | 0.01 | 0.00 | -0.01 | sell |
| DIMENSIONAL FUND ADVISORS LP | 798,462 | 961,083 | +162,621 | 0.00 | 0.00 | -0.00 | buy |
| FMR LLC | 63,570 | 937,368 | +873,798 | 0.00 | 0.00 | +0.00 | buy |
| SPHERA FUNDS MANAGEMENT LTD. | 0 | 926,004 | +926,004 | 0.00 | 0.40 | +0.40 | buy |
| Nuveen, LLC | 674,915 | 895,304 | +220,389 | 0.00 | 0.00 | -0.00 | buy |
| Alyeska Investment Group, L.P. | 617,211 | 617,211 | 0 | 0.01 | 0.00 | -0.00 | hold |
| NORTHERN TRUST CORP | 376,503 | 550,266 | +173,763 | 0.00 | 0.00 | -0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 18,022 | 399,542 | +381,520 | 0.00 | 0.00 | +0.00 | buy |
| Hennion & Walsh Asset Management, Inc. | 0 | 396,726 | +396,726 | 0.00 | 0.03 | +0.03 | buy |
| SummitTX Capital, L.P. | 379,765 | 352,284 | -27,481 | 0.05 | 0.03 | -0.03 | sell |
| JPMORGAN CHASE & CO | 331,818 | 328,015 | -3,803 | 0.00 | 0.00 | -0.00 | sell |
| Burkehill Global Management, LP | 300,000 | 300,000 | 0 | 0.07 | 0.03 | -0.03 | hold |
| RENAISSANCE TECHNOLOGIES LLC | 739,942 | 297,443 | -442,499 | 0.01 | 0.00 | -0.00 | sell |
| ADAR1 Capital Management, LLC | 52,745 | 272,745 | +220,000 | 0.01 | 0.04 | +0.02 | buy |
| Cerity Partners LLC | 247,912 | 271,582 | +23,670 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 475,612 | 236,133 | -239,479 | 0.00 | 0.00 | -0.00 | sell |
| Sixth Street Partners Management Company, L.P. | 0 | 206,969 | +206,969 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 145,342 | 206,969 | +61,627 | 0.00 | 0.00 | -0.00 | buy |
| IEQ CAPITAL, LLC | 114,038 | 203,363 | +89,325 | 0.00 | 0.00 | +0.00 | buy |
| Caption Management, LLC | 635,024 | 193,018 | -442,006 | 0.14 | 0.02 | -0.12 | sell |
| Soleus Capital Management, L.P. | 1,066,960 | 188,102 | -878,858 | 0.19 | 0.02 | -0.17 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 169,144 | 170,575 | +1,431 | 0.00 | 0.00 | -0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 0 | 165,156 | +165,156 | 0.00 | 0.01 | +0.01 | buy |
| DIADEMA PARTNERS LP | 166,637 | 146,637 | -20,000 | 0.31 | 0.16 | -0.15 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 140,060 | 144,428 | +4,368 | 0.00 | 0.00 | -0.00 | buy |
| Bank of New York Mellon Corp | 107,331 | 138,831 | +31,500 | 0.00 | 0.00 | -0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 28,796 | 138,196 | +109,400 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 299,700 | 135,601 | -164,099 | 0.02 | 0.00 | -0.02 | sell |
| Point72 Asset Management, L.P. | 1,047,385 | 134,806 | -912,579 | 0.01 | 0.00 | -0.01 | sell |
| Invesco Ltd. | 19,647 | 134,483 | +114,836 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 32,793 | 128,423 | +95,630 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 65,037 | 116,801 | +51,764 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 31,645 | 114,445 | +82,800 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 113,474 | +113,474 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 0 | 113,049 | +113,049 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 74,530 | 108,220 | +33,690 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 93,132 | 96,423 | +3,291 | 0.00 | 0.00 | -0.00 | buy |
| FEDERATED HERMES, INC. | 61,350 | 90,850 | +29,500 | 0.00 | 0.00 | -0.00 | buy |
| ExodusPoint Capital Management, LP | 26,445 | 90,413 | +63,968 | 0.00 | 0.00 | +0.00 | buy |
| CARY STREET PARTNERS FINANCIAL LLC | 0 | 85,000 | +85,000 | 0.00 | 0.01 | +0.01 | buy |
| JANE STREET GROUP, LLC | 554,007 | 73,736 | -480,271 | 0.00 | 0.00 | -0.00 | sell |
| RHUMBLINE ADVISERS | 62,685 | 71,888 | +9,203 | 0.00 | 0.00 | -0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 17,084 | 68,934 | +51,850 | 0.00 | 0.00 | +0.00 | buy |
| Quantbot Technologies LP | 331 | 68,771 | +68,440 | 0.00 | 0.01 | +0.01 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 32,799 | 63,680 | +30,881 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 20,228 | 62,103 | +41,875 | 0.00 | 0.00 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 69,087 | 59,788 | -9,299 | 0.00 | 0.00 | -0.00 | sell |
| CANADA PENSION PLAN INVESTMENT BOARD | 59,700 | 59,700 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SIMPLEX TRADING, LLC | 0 | 58,608 | +58,608 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 59,481 | 57,443 | -2,038 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 30,884 | 55,209 | +24,325 | 0.00 | 0.00 | -0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 34,768 | 54,629 | +19,861 | 0.00 | 0.00 | -0.00 | buy |
| CIBC WORLD MARKET INC. | 53,000 | 53,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| WINTON GROUP Ltd | 0 | 52,400 | +52,400 | 0.00 | 0.01 | +0.01 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 50,078 | +50,078 | 0.00 | 0.01 | +0.01 | buy |
| Pale Fire Capital SE | 0 | 43,000 | +43,000 | 0.00 | 0.01 | +0.01 | buy |
| Next Level Private LLC | 41,700 | 41,700 | 0 | 0.04 | 0.02 | -0.02 | hold |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 41,216 | 41,216 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MetLife Investment Management, LLC | 26,668 | 39,798 | +13,130 | 0.00 | 0.00 | -0.00 | buy |
| HighTower Advisors, LLC | 38,465 | 37,698 | -767 | 0.00 | 0.00 | -0.00 | sell |
| Persistent Asset Partners Ltd | 42,124 | 37,374 | -4,750 | 0.07 | 0.04 | -0.04 | sell |
| CITIGROUP INC | 36,107 | 35,636 | -471 | 0.00 | 0.00 | -0.00 | sell |
| Velan Capital Investment Management LP | 33,000 | 33,000 | 0 | 0.09 | 0.06 | -0.03 | hold |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 23,091 | 30,652 | +7,561 | 0.00 | 0.00 | -0.00 | buy |
| STRS OHIO | 21,700 | 26,500 | +4,800 | 0.00 | 0.00 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 77,636 | 26,467 | -51,169 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 16,373 | 25,957 | +9,584 | 0.00 | 0.00 | -0.00 | buy |
| CAPTRUST FINANCIAL ADVISORS | 0 | 25,211 | +25,211 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 3,589 | 25,166 | +21,577 | 0.00 | 0.00 | +0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 24,782 | 23,067 | -1,715 | 0.00 | 0.00 | -0.00 | sell |
| Corient Private Wealth LLC | 0 | 22,675 | +22,675 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 22,557 | +22,557 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Trading LLC | 20,000 | 20,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 13,445 | 19,520 | +6,075 | 0.00 | 0.00 | -0.00 | buy |
| Brevan Howard Capital Management LP | 0 | 19,504 | +19,504 | 0.00 | 0.00 | +0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 11,142 | 18,549 | +7,407 | 0.00 | 0.00 | -0.00 | buy |
| BRIGHTON JONES LLC | 0 | 18,476 | +18,476 | 0.00 | 0.00 | +0.00 | buy |
| Ethic Inc. | 35,451 | 17,879 | -17,572 | 0.00 | 0.00 | -0.00 | sell |
| Focus Partners Wealth | 0 | 17,370 | +17,370 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 17,006 | +17,006 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 19,270 | 16,533 | -2,737 | 0.01 | 0.00 | -0.00 | sell |
| INTECH INVESTMENT MANAGEMENT LLC | 14,529 | 16,390 | +1,861 | 0.00 | 0.00 | -0.00 | buy |
| HB Wealth Management, LLC | 0 | 16,078 | +16,078 | 0.00 | 0.00 | +0.00 | buy |
| Centiva Capital, LP | 0 | 16,024 | +16,024 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 13,726 | 13,726 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Jain Global LLC | 0 | 13,566 | +13,566 | 0.00 | 0.00 | +0.00 | buy |