| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 172,235 | +172,235 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 0 | 126,539 | +126,539 | 0.00 | 0.00 | +0.00 | buy |
| 683 Capital Management, LLC | 0 | 120,773 | +120,773 | 0.00 | 0.03 | +0.03 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 116,502 | +116,502 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 105,301 | +105,301 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 0 | 93,616 | +93,616 | 0.00 | 0.00 | +0.00 | buy |
| Informed Momentum Co LLC | 0 | 77,182 | +77,182 | 0.00 | 0.02 | +0.02 | buy |
| MARSHALL WACE, LLP | 0 | 62,911 | +62,911 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 33,099 | +33,099 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asset Management, L.P. | 0 | 30,367 | +30,367 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 0 | 24,859 | +24,859 | 0.00 | 0.00 | +0.00 | buy |
| OMERS ADMINISTRATION Corp | 0 | 24,400 | +24,400 | 0.00 | 0.00 | +0.00 | buy |
| FIFTH LANE CAPITAL, LP | 0 | 17,700 | +17,700 | 0.00 | 0.06 | +0.06 | buy |
| Lighthouse Investment Partners, LLC | 0 | 15,720 | +15,720 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 965,018 | 978,781 | +13,763 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 204,687 | 217,568 | +12,881 | 0.00 | 0.00 | -0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 3,626 | 11,100 | +7,474 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 110,187 | 115,627 | +5,440 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 4,832 | +4,832 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 55,642 | 56,182 | +540 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 317 | +317 | 0.00 | 0.00 | +0.00 | buy |
| ADVENT INTERNATIONAL, L.P. | 577,777 | 577,777 | 0 | 0.04 | 0.03 | -0.00 | hold |
| Legato Capital Management LLC | 14,684 | 14,684 | 0 | 0.01 | 0.00 | -0.00 | hold |
| Bain Capital Life Sciences Investors, LLC | 8,434,560 | 8,434,560 | 0 | 1.87 | 1.87 | +0.00 | hold |
| ABG-WTT Global Life Science Capital Partners GP Ltd | 1,848,296 | 1,848,296 | 0 | 33.06 | 35.62 | +2.56 | hold |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 62,326 | 62,326 | 0 | 0.03 | 0.03 | -0.00 | hold |
| AMERICAN CENTURY COMPANIES INC | 16,922 | 16,922 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RESOURCES MANAGEMENT CORP /CT/ /ADV | 500 | 500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 91,474 | 91,474 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SBI Securities Co., Ltd. | 17 | 15 | -2 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 47,726 | 40,487 | -7,239 | 0.00 | 0.00 | -0.00 | sell |
| Hudson Bay Capital Management LP | 11,461 | 0 | -11,461 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 22,165 | 0 | -22,165 | 0.00 | 0.00 | -0.00 | sell |
| Evernest Financial Advisors, LLC | 200,234 | 125,000 | -75,234 | 0.19 | 0.10 | -0.09 | sell |
| Schonfeld Strategic Advisors LLC | 646,579 | 352,433 | -294,146 | 0.02 | 0.01 | -0.01 | sell |
| BlackRock, Inc. | 483,871 | 156,666 | -327,205 | 0.00 | 0.00 | -0.00 | sell |
| Parkman Healthcare Partners LLC | 913,443 | 354,465 | -558,978 | 0.34 | 0.10 | -0.24 | sell |