| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Affinity Asset Advisors, LLC | 0 | 748,382 | +748,382 | 0.00 | 0.62 | +0.62 | buy |
| Kynam Capital Management, LP | 0 | 479,590 | +479,590 | 0.00 | 0.36 | +0.36 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 418,196 | +418,196 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 0 | 375,786 | +375,786 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 337,953 | +337,953 | 0.00 | 0.01 | +0.01 | buy |
| Velan Capital Investment Management LP | 0 | 312,000 | +312,000 | 0.00 | 2.10 | +2.10 | buy |
| Merck & Co., Inc. | 2,723,509 | 272,351 | -2,451,158 | 1.04 | 1.14 | +0.10 | sell |
| Vestal Point Capital, LP | 0 | 243,000 | +243,000 | 0.00 | 0.10 | +0.10 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 230,049 | +230,049 | 0.00 | 0.00 | +0.00 | buy |
| Samsara BioCapital, LLC | 0 | 204,503 | +204,503 | 0.00 | 0.24 | +0.24 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 0 | 200,000 | +200,000 | 0.00 | 0.00 | +0.00 | buy |
| Eversept Partners, LP | 0 | 193,571 | +193,571 | 0.00 | 0.13 | +0.13 | buy |
| Opaleye Management Inc. | 0 | 190,671 | +190,671 | 0.00 | 0.29 | +0.29 | buy |
| Point72 Asset Management, L.P. | 0 | 179,088 | +179,088 | 0.00 | 0.00 | +0.00 | buy |
| TANG CAPITAL MANAGEMENT LLC | 0 | 139,617 | +139,617 | 0.00 | 0.08 | +0.08 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 122,865 | +122,865 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 0 | 117,437 | +117,437 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 89,067 | +89,067 | 0.00 | 0.09 | +0.09 | buy |
| MARSHALL WACE, LLP | 0 | 85,615 | +85,615 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 0 | 83,979 | +83,979 | 0.00 | 0.00 | +0.00 | buy |
| ACUTA CAPITAL PARTNERS, LLC | 0 | 67,451 | +67,451 | 0.00 | 0.53 | +0.53 | buy |
| ADAR1 Capital Management, LLC | 0 | 67,077 | +67,077 | 0.00 | 0.06 | +0.06 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 46,492 | +46,492 | 0.00 | 0.00 | +0.00 | buy |
| Fisher Asset Management, LLC | 0 | 35,305 | +35,305 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 0 | 34,266 | +34,266 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 0 | 32,085 | +32,085 | 0.00 | 0.00 | +0.00 | buy |
| Shay Capital LLC | 0 | 24,255 | +24,255 | 0.00 | 0.05 | +0.05 | buy |
| JANE STREET GROUP, LLC | 0 | 22,945 | +22,945 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 18,034 | +18,034 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 17,580 | +17,580 | 0.00 | 0.00 | +0.00 | buy |
| AJU IB Investment Co., Ltd. | 175,000 | 17,500 | -157,500 | 0.13 | 0.89 | +0.76 | sell |
| Invesco Ltd. | 0 | 16,970 | +16,970 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 0 | 15,669 | +15,669 | 0.00 | 0.00 | +0.00 | buy |
| RBF Capital, LLC | 0 | 15,272 | +15,272 | 0.00 | 0.01 | +0.01 | buy |
| NORTHERN TRUST CORP | 0 | 14,379 | +14,379 | 0.00 | 0.00 | +0.00 | buy |
| OMERS ADMINISTRATION Corp | 0 | 11,023 | +11,023 | 0.00 | 0.00 | +0.00 | buy |
| State of Tennessee, Department of Treasury | 0 | 7,400 | +7,400 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 0 | 1,499 | +1,499 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 0 | 1,108 | +1,108 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 1,043 | +1,043 | 0.00 | 0.00 | +0.00 | buy |
| FNY Investment Advisers, LLC | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| Physician Wealth Advisors, Inc. | 0 | 182 | +182 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 111 | +111 | 0.00 | 0.00 | +0.00 | buy |
| Avion Wealth | 0 | 72 | +72 | 0.00 | 0.00 | 0.00 | buy |
| Fortitude Family Office, LLC | 0 | 56 | +56 | 0.00 | 0.00 | +0.00 | buy |
| Bogart Wealth, LLC | 500 | 50 | -450 | 0.00 | 0.00 | +0.00 | sell |
| Parallel Advisors, LLC | 465 | 47 | -418 | 0.00 | 0.00 | +0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 0 | 44 | +44 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 454 | 31 | -423 | 0.00 | 0.00 | -0.00 | sell |
| HighMark Wealth Management LLC | 0 | 23 | +23 | 0.00 | 0.00 | +0.00 | buy |
| Arax Advisory Partners | 0 | 3 | +3 | 0.00 | 0.00 | +0.00 | buy |
| COMERICA BANK | 0 | 3 | +3 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 2 | +2 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 258,991 | 0 | -258,991 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 3,682,986 | 0 | -3,682,986 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 1,424,797 | 0 | -1,424,797 | 0.00 | 0.00 | -0.00 | sell |
| OMERS ADMINISTRATION Corp | 95,150 | 0 | -95,150 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 42,900 | 0 | -42,900 | 0.00 | 0.00 | -0.00 | sell |
| RBF Capital, LLC | 152,714 | 0 | -152,714 | 0.01 | 0.00 | -0.01 | sell |
| PRUDENTIAL FINANCIAL INC | 35,500 | 0 | -35,500 | 0.00 | 0.00 | -0.00 | sell |
| BLUEFIN CAPITAL MANAGEMENT, LLC | 34,934 | 0 | -34,934 | 0.01 | 0.00 | -0.01 | sell |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2,000,000 | 0 | -2,000,000 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 1,741 | 0 | -1,741 | 0.00 | 0.00 | -0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 354,449 | 0 | -354,449 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 396,785 | 0 | -396,785 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 820,948 | 0 | -820,948 | 0.00 | 0.00 | -0.00 | sell |
| TANG CAPITAL MANAGEMENT LLC | 2,828,717 | 0 | -2,828,717 | 0.09 | 0.00 | -0.09 | sell |
| MILLENNIUM MANAGEMENT LLC | 4,524,350 | 0 | -4,524,350 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 118,443 | 0 | -118,443 | 0.00 | 0.00 | -0.00 | sell |
| GSA CAPITAL PARTNERS LLP | 174,843 | 0 | -174,843 | 0.01 | 0.00 | -0.01 | sell |
| DAFNA Capital Management LLC | 437,079 | 0 | -437,079 | 0.09 | 0.00 | -0.09 | sell |
| TWO SIGMA ADVISERS, LP | 239,400 | 0 | -239,400 | 0.00 | 0.00 | -0.00 | sell |
| Savant Capital, LLC | 37,713 | 0 | -37,713 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 24,017 | 0 | -24,017 | 0.00 | 0.00 | -0.00 | sell |
| Ground Swell Capital, LLC | 14,345 | 0 | -14,345 | 0.03 | 0.00 | -0.03 | sell |
| CWM, LLC | 25,236 | 0 | -25,236 | 0.00 | 0.00 | -0.00 | sell |
| Cerity Partners LLC | 68,061 | 0 | -68,061 | 0.00 | 0.00 | -0.00 | sell |
| SUVRETTA CAPITAL MANAGEMENT, LLC | 6,488,324 | 0 | -6,488,324 | 0.17 | 0.00 | -0.17 | sell |
| Mirae Asset Global Investments Co., Ltd. | 3,277 | 0 | -3,277 | 0.00 | 0.00 | -0.00 | sell |
| Advisory Services Network, LLC | 147 | 0 | -147 | 0.00 | 0.00 | -0.00 | sell |
| Arax Advisory Partners | 3,843 | 0 | -3,843 | 0.00 | 0.00 | -0.00 | sell |
| Vontobel Holding Ltd. | 50,000 | 0 | -50,000 | 0.00 | 0.00 | -0.00 | sell |
| UBS Group AG | 1,845,839 | 0 | -1,845,839 | 0.00 | 0.00 | -0.00 | sell |
| IFP Advisors, Inc | 21 | 0 | -21 | 0.00 | 0.00 | -0.00 | sell |
| Eversept Partners, LP | 2,291,313 | 0 | -2,291,313 | 0.15 | 0.00 | -0.15 | sell |
| Aberdeen Group plc | 69,389 | 0 | -69,389 | 0.00 | 0.00 | -0.00 | sell |
| Shay Capital LLC | 312,051 | 0 | -312,051 | 0.05 | 0.00 | -0.05 | sell |
| Qube Research & Technologies Ltd | 65,226 | 0 | -65,226 | 0.00 | 0.00 | -0.00 | sell |
| Rockefeller Capital Management L.P. | 2,365 | 0 | -2,365 | 0.00 | 0.00 | -0.00 | sell |
| FNY Investment Advisers, LLC | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| Samsara BioCapital, LLC | 2,196,814 | 0 | -2,196,814 | 0.25 | 0.00 | -0.25 | sell |
| Quantinno Capital Management LP | 11,139 | 0 | -11,139 | 0.00 | 0.00 | -0.00 | sell |
| Vanguard Personalized Indexing Management, LLC | 60,184 | 0 | -60,184 | 0.00 | 0.00 | -0.00 | sell |
| Affinity Asset Advisors, LLC | 752,722 | 0 | -752,722 | 0.06 | 0.00 | -0.06 | sell |
| IEQ CAPITAL, LLC | 59,752 | 0 | -59,752 | 0.00 | 0.00 | -0.00 | sell |
| Avion Wealth | 716 | 0 | -716 | 0.00 | 0.00 | 0.00 | sell |
| Physician Wealth Advisors, Inc. | 1,304 | 0 | -1,304 | 0.00 | 0.00 | -0.00 | sell |
| HighMark Wealth Management LLC | 225 | 0 | -225 | 0.00 | 0.00 | -0.00 | sell |
| Revolve Wealth Partners, LLC | 11,002 | 0 | -11,002 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 19,131 | 0 | -19,131 | 0.00 | 0.00 | -0.00 | sell |