| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | 3,108,194 | 3,235,660 | +127,466 | 0.01 | 0.01 | +0.00 | buy |
| SANDS CAPITAL MANAGEMENT, LLC | 3,016,207 | 2,915,527 | -100,680 | 1.07 | 1.29 | +0.21 | sell |
| BlackRock, Inc. | 2,703,345 | 2,749,635 | +46,290 | 0.01 | 0.01 | +0.00 | buy |
| Artisan Partners Limited Partnership | 2,814,280 | 2,740,841 | -73,439 | 0.48 | 0.63 | +0.15 | sell |
| BNP Paribas Asset Management Holding S.A. | 2,499,999 | 2,500,000 | +1 | 0.01 | 0.01 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 0 | 2,000,000 | +2,000,000 | 0.00 | 0.01 | +0.01 | buy |
| Capital Research Global Investors | 2,202,622 | 1,506,864 | -695,758 | 0.05 | 0.05 | -0.00 | sell |
| STATE STREET CORP | 917,688 | 868,525 | -49,163 | 0.00 | 0.01 | +0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 750,369 | 767,336 | +16,967 | 0.01 | 0.01 | +0.00 | buy |
| BLAIR WILLIAM & CO/IL | 789,999 | 739,331 | -50,668 | 0.25 | 0.32 | +0.07 | sell |
| BNP Paribas Asset Management Holding S.A. | 879,816 | 734,624 | -145,192 | 0.25 | 0.28 | +0.03 | sell |
| MACKENZIE FINANCIAL CORP | 1,155,954 | 729,813 | -426,141 | 0.17 | 0.15 | -0.03 | sell |
| EVENTIDE ASSET MANAGEMENT, LLC | 740,062 | 691,573 | -48,489 | 1.54 | 1.87 | +0.32 | sell |
| Champlain Investment Partners, LLC | 822,791 | 661,232 | -161,559 | 0.62 | 0.71 | +0.09 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 903,084 | 607,652 | -295,432 | 0.02 | 0.02 | -0.01 | sell |
| FULLER & THALER ASSET MANAGEMENT, INC. | 518,240 | 586,478 | +68,238 | 0.21 | 0.33 | +0.12 | buy |
| BESSEMER GROUP INC | 574,053 | 569,196 | -4,857 | 0.11 | 0.14 | +0.03 | sell |
| JPMORGAN CHASE & CO | 562,514 | 563,201 | +687 | 0.00 | 0.01 | +0.00 | buy |
| Stephens Investment Management Group LLC | 520,582 | 552,916 | +32,334 | 0.79 | 1.12 | +0.34 | buy |
| Allspring Global Investments Holdings, LLC | 518,618 | 434,343 | -84,275 | 0.10 | 0.11 | +0.01 | sell |
| FMR LLC | 463,223 | 420,201 | -43,022 | 0.00 | 0.00 | +0.00 | sell |
| WELLINGTON MANAGEMENT GROUP LLP | 165,642 | 395,316 | +229,674 | 0.00 | 0.01 | +0.01 | buy |
| GOLDMAN SACHS GROUP INC | 433,780 | 394,613 | -39,167 | 0.01 | 0.01 | +0.00 | sell |
| Bank of New York Mellon Corp | 357,501 | 349,338 | -8,163 | 0.01 | 0.01 | +0.00 | sell |
| BANK OF AMERICA CORP /DE/ | 371,920 | 347,632 | -24,288 | 0.00 | 0.00 | +0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 399,746 | 336,307 | -63,439 | 0.04 | 0.05 | +0.01 | sell |
| FRED ALGER MANAGEMENT, LLC | 249,714 | 325,543 | +75,829 | 0.15 | 0.22 | +0.08 | buy |
| Point72 Asset Management, L.P. | 420,303 | 322,098 | -98,205 | 0.12 | 0.12 | -0.01 | sell |
| Holocene Advisors, LP | 14,747 | 313,094 | +298,347 | 0.00 | 0.12 | +0.11 | buy |
| BRAIDWELL LP | 556,391 | 300,029 | -256,362 | 2.05 | 1.58 | -0.47 | sell |
| JENNISON ASSOCIATES LLC | 280,187 | 297,492 | +17,305 | 0.02 | 0.03 | +0.01 | buy |
| SEI INVESTMENTS CO | 312,762 | 290,634 | -22,128 | 0.04 | 0.05 | +0.01 | sell |
| WESTFIELD CAPITAL MANAGEMENT CO LP | 617,078 | 290,570 | -326,508 | 0.31 | 0.19 | -0.13 | sell |
| NORTHERN TRUST CORP | 292,009 | 289,317 | -2,692 | 0.00 | 0.01 | +0.00 | sell |
| LORD, ABBETT & CO. LLC | 258,628 | 287,476 | +28,848 | 0.10 | 0.14 | +0.05 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 254,579 | 271,467 | +16,888 | 0.00 | 0.01 | +0.00 | buy |
| SEI INVESTMENTS CO | 155,000 | 269,000 | +114,000 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 0 | 267,603 | +267,603 | 0.00 | 0.09 | +0.09 | buy |
| LOOMIS SAYLES & CO L P | 0 | 255,517 | +255,517 | 0.00 | 0.05 | +0.05 | buy |
| D. E. Shaw & Co., Inc. | 0 | 247,836 | +247,836 | 0.00 | 0.04 | +0.04 | buy |
| Rock Springs Capital Management LP | 254,300 | 242,500 | -11,800 | 1.52 | 2.33 | +0.80 | sell |
| NEXT CENTURY GROWTH INVESTORS LLC | 208,220 | 224,863 | +16,643 | 1.94 | 2.67 | +0.74 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 314,690 | 220,969 | -93,721 | 0.03 | 0.03 | -0.00 | sell |
| BARCLAYS PLC | 200,482 | 215,289 | +14,807 | 0.01 | 0.01 | +0.00 | buy |
| Nuveen, LLC | 92,729 | 214,012 | +121,283 | 0.00 | 0.01 | +0.01 | buy |
| Ophir Asset Management Pty Ltd | 377,682 | 202,084 | -175,598 | 6.91 | 4.50 | -2.40 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 196,358 | 195,642 | -716 | 0.02 | 0.03 | +0.01 | sell |
| DEUTSCHE BANK AG\ | 204,915 | 192,190 | -12,725 | 0.01 | 0.01 | +0.00 | sell |
| First Light Asset Management, LLC | 325,046 | 187,355 | -137,691 | 3.89 | 3.74 | -0.15 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 3,478 | 183,257 | +179,779 | 0.00 | 0.02 | +0.02 | buy |
| MORGAN STANLEY | 232,669 | 177,898 | -54,771 | 0.00 | 0.00 | +0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 160,886 | 170,013 | +9,127 | 0.02 | 0.03 | +0.01 | buy |
| CITIGROUP INC | 185,142 | 166,744 | -18,398 | 0.01 | 0.02 | +0.00 | sell |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 0 | 161,646 | +161,646 | 0.00 | 0.20 | +0.20 | buy |
| Squarepoint Ops LLC | 29,959 | 160,449 | +130,490 | 0.01 | 0.05 | +0.05 | buy |
| Freestone Grove Partners LP | 136,972 | 154,317 | +17,345 | 0.15 | 0.18 | +0.03 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 22,100 | 141,200 | +119,100 | 0.00 | 0.03 | +0.03 | buy |
| SEGALL BRYANT & HAMILL, LLC | 130,748 | 137,293 | +6,545 | 0.21 | 0.30 | +0.09 | buy |
| AMERIPRISE FINANCIAL INC | 68,677 | 135,288 | +66,611 | 0.00 | 0.01 | +0.00 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 0 | 126,455 | +126,455 | 0.00 | 0.01 | +0.01 | buy |
| RAYMOND JAMES FINANCIAL INC | 110,126 | 116,467 | +6,341 | 0.00 | 0.01 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 43,717 | 110,727 | +67,010 | 0.06 | 0.18 | +0.12 | buy |
| FRONTIER CAPITAL MANAGEMENT CO LLC | 224,910 | 106,415 | -118,495 | 0.26 | 0.15 | -0.11 | sell |
| CITADEL ADVISORS LLC | 3,102 | 100,023 | +96,921 | 0.00 | 0.01 | +0.01 | buy |
| Invesco Ltd. | 22,216 | 94,298 | +72,082 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 45,753 | 88,168 | +42,415 | 0.01 | 0.02 | +0.01 | buy |
| PFM Health Sciences, LP | 0 | 88,157 | +88,157 | 0.00 | 1.18 | +1.18 | buy |
| Verition Fund Management LLC | 166,472 | 87,511 | -78,961 | 0.10 | 0.08 | -0.02 | sell |
| OBERWEIS ASSET MANAGEMENT INC/ | 0 | 81,200 | +81,200 | 0.00 | 0.54 | +0.54 | buy |
| C WorldWide Group Holding A/S | 80,000 | 80,000 | 0 | 0.10 | 0.17 | +0.06 | hold |
| PRINCIPAL FINANCIAL GROUP INC | 50,449 | 79,169 | +28,720 | 0.00 | 0.01 | +0.00 | buy |
| ROYAL BANK OF CANADA | 7,573 | 77,721 | +70,148 | 0.00 | 0.00 | +0.00 | buy |
| WCM INVESTMENT MANAGEMENT, LLC | 138,437 | 77,170 | -61,267 | 0.04 | 0.03 | -0.01 | sell |
| PEREGRINE CAPITAL MANAGEMENT LLC | 83,055 | 76,594 | -6,461 | 0.29 | 0.36 | +0.07 | sell |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 100,000 | 75,000 | -25,000 | 0.02 | 0.02 | +0.00 | sell |
| Engineers Gate Manager LP | 54,576 | 74,842 | +20,266 | 0.10 | 0.14 | +0.05 | buy |
| M&G Plc | 0 | 74,398 | +74,398 | 0.00 | 0.06 | +0.06 | buy |
| Walleye Capital LLC | 0 | 73,822 | +73,822 | 0.00 | 0.11 | +0.11 | buy |
| TimesSquare Capital Management, LLC | 0 | 71,660 | +71,660 | 0.00 | 0.16 | +0.16 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 75,040 | 68,475 | -6,565 | 0.02 | 0.03 | +0.01 | sell |
| Trexquant Investment LP | 20,791 | 65,217 | +44,426 | 0.03 | 0.11 | +0.09 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 55,108 | 64,668 | +9,560 | 0.01 | 0.02 | +0.01 | buy |
| Jump Financial, LLC | 0 | 62,795 | +62,795 | 0.00 | 0.13 | +0.13 | buy |
| Amundi | 95,854 | 60,608 | -35,246 | 0.00 | 0.00 | -0.00 | sell |
| Swiss National Bank | 60,700 | 60,000 | -700 | 0.00 | 0.01 | +0.00 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 3,689 | 59,899 | +56,210 | 0.00 | 0.01 | +0.01 | buy |
| MACQUARIE GROUP LTD | 54,917 | 57,523 | +2,606 | 0.01 | 0.01 | +0.00 | buy |
| FIRST TRUST ADVISORS LP | 33,860 | 56,197 | +22,337 | 0.00 | 0.01 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 0 | 53,926 | +53,926 | 0.00 | 0.03 | +0.03 | buy |
| Point72 (DIFC) Ltd | 72,129 | 50,000 | -22,129 | 0.73 | 0.61 | -0.11 | sell |
| SILVERCREST ASSET MANAGEMENT GROUP LLC | 94,881 | 49,123 | -45,758 | 0.07 | 0.05 | -0.02 | sell |
| RHUMBLINE ADVISERS | 45,946 | 48,477 | +2,531 | 0.00 | 0.01 | +0.00 | buy |
| FEDERATED HERMES, INC. | 0 | 48,424 | +48,424 | 0.00 | 0.01 | +0.01 | buy |
| CASTLEARK MANAGEMENT LLC | 48,290 | 48,180 | -110 | 0.18 | 0.22 | +0.05 | sell |
| Qube Research & Technologies Ltd | 0 | 47,425 | +47,425 | 0.00 | 0.01 | +0.01 | buy |
| PRUDENTIAL FINANCIAL INC | 2,275 | 45,825 | +43,550 | 0.00 | 0.01 | +0.01 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 10,653 | 44,713 | +34,060 | 0.00 | 0.02 | +0.01 | buy |
| Legal & General Group Plc | 42,911 | 44,004 | +1,093 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 42,414 | 41,864 | -550 | 0.07 | 0.17 | +0.10 | sell |
| Integral Health Asset Management, LLC | 0 | 40,000 | +40,000 | 0.00 | 0.58 | +0.58 | buy |