| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BVF INC/IL | 6,293,282 | 6,293,282 | 0 | 0.32 | 0.62 | +0.30 | hold |
| BlackRock, Inc. | 3,627,208 | 4,382,245 | +755,037 | 0.00 | 0.00 | +0.00 | buy |
| Ensign Peak Advisors, Inc | 2,464,919 | 2,464,919 | 0 | 0.01 | 0.01 | +0.01 | hold |
| Zimmer Partners, LP | 2,384,228 | 1,875,000 | -509,228 | 0.09 | 0.14 | +0.05 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 1,421,617 | 1,791,783 | +370,166 | 0.00 | 0.00 | +0.00 | buy |
| SPHERA FUNDS MANAGEMENT LTD. | 2,132,131 | 1,772,131 | -360,000 | 0.67 | 0.94 | +0.27 | sell |
| Catalio Capital Management, LP | 1,259,820 | 1,639,816 | +379,996 | 0.34 | 1.06 | +0.72 | buy |
| Blue Owl Capital Holdings LP | 1,929,912 | 1,419,912 | -510,000 | 0.90 | 1.18 | +0.28 | sell |
| STATE STREET CORP | 773,885 | 1,154,671 | +380,786 | 0.00 | 0.00 | +0.00 | buy |
| AWM Investment Company, Inc. | 1,100,000 | 1,100,000 | 0 | 0.16 | 0.38 | +0.21 | hold |
| Jefferies Financial Group Inc. | 1,580,625 | 1,094,456 | -486,169 | 0.02 | 0.04 | +0.02 | sell |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | 1,039,275 | 1,039,275 | 0 | 0.24 | 0.54 | +0.30 | hold |
| ADAR1 Capital Management, LLC | 1,821,812 | 974,421 | -847,391 | 0.21 | 0.18 | -0.03 | sell |
| BANK OF AMERICA CORP /DE/ | 0 | 869,544 | +869,544 | 0.00 | 0.00 | +0.00 | buy |
| Sanofi | 814,980 | 814,980 | 0 | 0.40 | 0.75 | +0.35 | hold |
| CM Management, LLC | 650,000 | 650,000 | 0 | 0.83 | 1.67 | +0.85 | hold |
| 22NW, LP | 636,364 | 636,364 | 0 | 0.40 | 1.34 | +0.94 | hold |
| SG Americas Securities, LLC | 627,392 | 635,845 | +8,453 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 593,131 | 547,447 | -45,684 | 0.00 | 0.00 | +0.00 | sell |
| NORTHERN TRUST CORP | 429,813 | 543,842 | +114,029 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 198,712 | 370,090 | +171,378 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 195,757 | 228,557 | +32,800 | 0.01 | 0.01 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 173,131 | 194,022 | +20,891 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 60,215 | 172,417 | +112,202 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 132,902 | 144,148 | +11,246 | 0.00 | 0.00 | +0.00 | buy |
| BIT Capital GmbH | 0 | 134,000 | +134,000 | 0.00 | 0.02 | +0.02 | buy |
| DEUTSCHE BANK AG\ | 0 | 89,350 | +89,350 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 76,292 | 76,292 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Rockefeller Capital Management L.P. | 71,666 | 71,666 | 0 | 0.00 | 0.00 | +0.00 | hold |
| DIMENSIONAL FUND ADVISORS LP | 115,682 | 67,081 | -48,601 | 0.00 | 0.00 | +0.00 | sell |
| XTX Topco Ltd | 124,247 | 66,235 | -58,012 | 0.00 | 0.00 | -0.00 | sell |
| INGALLS & SNYDER LLC | 51,849 | 51,849 | 0 | 0.00 | 0.01 | +0.00 | hold |
| PRICE T ROWE ASSOCIATES INC /MD/ | 29,499 | 50,162 | +20,663 | 0.00 | 0.00 | +0.00 | buy |
| Cambridge Investment Research Advisors, Inc. | 0 | 48,202 | +48,202 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 44,617 | 47,626 | +3,009 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 0 | 42,105 | +42,105 | 0.00 | 0.00 | +0.00 | buy |
| Kera Capital Partners, Inc. | 39,770 | 39,908 | +138 | 0.01 | 0.02 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 68,906 | 36,569 | -32,337 | 0.00 | 0.00 | +0.00 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 26,755 | 35,054 | +8,299 | 0.00 | 0.00 | +0.00 | buy |
| Stonepine Capital Management, LLC | 893,100 | 35,000 | -858,100 | 1.07 | 0.09 | -0.97 | sell |
| Invesco Ltd. | 31,669 | 30,968 | -701 | 0.00 | 0.00 | +0.00 | sell |
| MARCO INVESTMENT MANAGEMENT LLC | 30,344 | 30,344 | 0 | 0.00 | 0.01 | +0.00 | hold |
| HOWARD FINANCIAL SERVICES, LTD. | 30,000 | 30,000 | 0 | 0.01 | 0.01 | +0.01 | hold |
| MITCHELL & PAHL PRIVATE WEALTH, LLC | 0 | 30,000 | +30,000 | 0.00 | 0.04 | +0.04 | buy |
| GROUP ONE TRADING LLC | 0 | 29,874 | +29,874 | 0.00 | 0.00 | +0.00 | buy |
| Cetera Investment Advisers | 26,584 | 28,347 | +1,763 | 0.00 | 0.00 | +0.00 | buy |
| KESTRA PRIVATE WEALTH SERVICES, LLC | 0 | 25,000 | +25,000 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 176,990 | 24,600 | -152,390 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 0 | 20,434 | +20,434 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 22,850 | 20,331 | -2,519 | 0.00 | 0.00 | +0.00 | sell |
| Baker Ellis Asset Management LLC | 0 | 19,000 | +19,000 | 0.00 | 0.01 | +0.01 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 11,883 | 16,053 | +4,170 | 0.00 | 0.00 | +0.00 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 17,684 | 15,142 | -2,542 | 0.00 | 0.00 | +0.00 | sell |
| JONES FINANCIAL COMPANIES LLLP | 0 | 15,000 | +15,000 | 0.00 | 0.00 | +0.00 | buy |
| BLAIR WILLIAM & CO/IL | 0 | 14,516 | +14,516 | 0.00 | 0.00 | +0.00 | buy |
| Revolve Wealth Partners, LLC | 0 | 14,143 | +14,143 | 0.00 | 0.01 | +0.01 | buy |
| BARCLAYS PLC | 87,472 | 13,816 | -73,656 | 0.00 | 0.00 | -0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 11,420 | 13,216 | +1,796 | 0.00 | 0.00 | +0.00 | buy |
| Waverly Advisors, LLC | 0 | 12,574 | +12,574 | 0.00 | 0.00 | +0.00 | buy |
| Relyea Zuckerberg Hanson LLC | 0 | 12,000 | +12,000 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 11,856 | 11,856 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Summit Financial, LLC | 11,500 | 11,500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ProShare Advisors LLC | 10,266 | 10,832 | +566 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 0 | 10,450 | +10,450 | 0.00 | 0.00 | +0.00 | buy |
| Susquehanna Portfolio Strategies, LLC | 0 | 10,132 | +10,132 | 0.00 | 0.00 | +0.00 | buy |
| GRANDFIELD & DODD, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| Ellis Investment Partners, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.01 | +0.01 | buy |
| Everhart Financial Group, Inc. | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| Forum Private Client Group LLC | 10,000 | 10,000 | 0 | 0.01 | 0.01 | +0.01 | hold |
| CWM, LLC | 2,011 | 9,944 | +7,933 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 5,333 | 7,000 | +1,667 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 5,984 | 5,984 | 0 | 0.00 | 0.00 | +0.00 | hold |
| FMR LLC | 4,686 | 5,620 | +934 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 10,781 | 5,295 | -5,486 | 0.00 | 0.00 | -0.00 | sell |
| SOA Wealth Advisors, LLC. | 0 | 4,566 | +4,566 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 27,351 | 4,249 | -23,102 | 0.00 | 0.00 | -0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 4,200 | 4,200 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,455 | 4,094 | +639 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 1,279 | 3,498 | +2,219 | 0.00 | 0.00 | +0.00 | buy |
| Navigoe, LLC | 0 | 2,569 | +2,569 | 0.00 | 0.00 | +0.00 | buy |
| Sterling Capital Management LLC | 3,659 | 2,344 | -1,315 | 0.00 | 0.00 | +0.00 | sell |
| Addison Advisors LLC | 1,300 | 1,300 | 0 | 0.00 | 0.00 | +0.00 | hold |
| GAMMA Investing LLC | 0 | 1,188 | +1,188 | 0.00 | 0.00 | +0.00 | buy |
| Steward Partners Investment Advisory, LLC | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 349 | 906 | +557 | 0.00 | 0.00 | +0.00 | buy |
| SIGNATUREFD, LLC | 0 | 500 | +500 | 0.00 | 0.00 | +0.00 | buy |
| Clearstead Advisors, LLC | 500 | 500 | 0 | 0.00 | 0.00 | +0.00 | hold |
| IMG Wealth Management, Inc. | 0 | 352 | +352 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 0 | 259 | +259 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 0 | 133 | +133 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 0 | 132 | +132 | 0.00 | 0.00 | +0.00 | buy |
| Root Financial Partners, LLC | 0 | 110 | +110 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 63 | 63 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ROTHSCHILD INVESTMENT LLC | 24 | 46 | +22 | 0.00 | 0.00 | +0.00 | buy |
| PITTENGER & ANDERSON INC | 0 | 35 | +35 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 0 | 32 | +32 | 0.00 | 0.00 | +0.00 | buy |
| Sunbelt Securities, Inc. | 0 | 26 | +26 | 0.00 | 0.00 | +0.00 | buy |
| Arax Advisory Partners | 0 | 23 | +23 | 0.00 | 0.00 | +0.00 | buy |
| IFP Advisors, Inc | 0 | 11 | +11 | 0.00 | 0.00 | +0.00 | buy |
| SJS Investment Consulting Inc. | 0 | 9 | +9 | 0.00 | 0.00 | +0.00 | buy |