| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ARMISTICE CAPITAL, LLC | 1,824,000 | 2,189,000 | +365,000 | 0.07 | 0.10 | +0.03 | buy |
| Woodline Partners LP | 603,993 | 689,340 | +85,347 | 0.01 | 0.01 | +0.00 | buy |
| VANGUARD GROUP INC | 674,520 | 695,418 | +20,898 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA SECURITIES, LLC | 0 | 11,780 | +11,780 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 61,973 | 69,173 | +7,200 | 0.00 | 0.00 | +0.00 | buy |
| INGALLS & SNYDER LLC | 51,849 | 51,849 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BVF INC/IL | 4,326,710 | 4,326,710 | 0 | 0.16 | 0.19 | +0.04 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 176,039 | 176,039 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Ensign Peak Advisors, Inc | 443,001 | 443,001 | 0 | 0.00 | 0.00 | +0.00 | hold |
| JMAC ENTERPRISES LLC | 58,041 | 58,041 | 0 | 0.02 | 0.02 | +0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| MERCER GLOBAL ADVISORS INC /ADV | 16,726 | 16,726 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 14,987 | 14,987 | 0 | 0.00 | 0.00 | +0.00 | hold |
| STATE STREET CORP | 44,692 | 44,692 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SIMPLEX TRADING, LLC | 3,623 | 3,223 | -400 | 0.00 | 0.00 | +0.00 | sell |
| Tower Research Capital LLC (TRC) | 8,443 | 5,636 | -2,807 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 27,150 | 22,867 | -4,283 | 0.00 | 0.00 | +0.00 | sell |
| GROUP ONE TRADING LLC | 4,850 | 22 | -4,828 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 47,428 | 39,900 | -7,528 | 0.00 | 0.00 | +0.00 | sell |
| Curi Capital, LLC | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 13,100 | 0 | -13,100 | 0.00 | 0.00 | -0.00 | sell |
| SVB FINANCIAL GROUP | 13,472 | 0 | -13,472 | 0.03 | 0.00 | -0.03 | sell |
| CM Management, LLC | 234,803 | 140,000 | -94,803 | 0.34 | 0.20 | -0.14 | sell |
| ROYAL BANK OF CANADA | 158,207 | 0 | -158,207 | 0.00 | 0.00 | -0.00 | sell |