| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| CITADEL ADVISORS LLC | 234,905 | 2,272,404 | +2,037,499 | 0.00 | 0.00 | +0.00 | buy |
| ORBIMED ADVISORS LLC | 0 | 2,000,000 | +2,000,000 | 0.00 | 0.07 | +0.07 | buy |
| Nantahala Capital Management, LLC | 0 | 1,750,000 | +1,750,000 | 0.00 | 0.31 | +0.31 | buy |
| Stonepine Capital Management, LLC | 0 | 1,462,296 | +1,462,296 | 0.00 | 2.08 | +2.08 | buy |
| MILLENNIUM MANAGEMENT LLC | 1,494,489 | 2,855,612 | +1,361,123 | 0.00 | 0.00 | +0.00 | buy |
| Altium Capital Management LLC | 0 | 1,212,882 | +1,212,882 | 0.00 | 0.97 | +0.97 | buy |
| Alta Fundamental Advisers LLC | 1,671,289 | 2,371,289 | +700,000 | 1.49 | 2.12 | +0.63 | buy |
| Lion Point Capital, LP | 1,650,207 | 2,300,207 | +650,000 | 2.46 | 7.87 | +5.41 | buy |
| Velan Capital Investment Management LP | 0 | 650,000 | +650,000 | 0.00 | 0.63 | +0.63 | buy |
| Monashee Investment Management LLC | 0 | 500,000 | +500,000 | 0.00 | 0.11 | +0.11 | buy |
| BANK OF MONTREAL /CAN/ | 0 | 273,100 | +273,100 | 0.00 | 0.00 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 0 | 202,460 | +202,460 | 0.00 | 0.10 | +0.10 | buy |
| BML Capital Management, LLC | 442,352 | 606,145 | +163,793 | 0.58 | 0.73 | +0.14 | buy |
| MORGAN STANLEY | 689,400 | 819,828 | +130,428 | 0.00 | 0.00 | +0.00 | buy |
| ENVESTNET ASSET MANAGEMENT INC | 20,670 | 51,833 | +31,163 | 0.00 | 0.00 | +0.00 | buy |
| Cetera Investment Advisers | 0 | 17,427 | +17,427 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 13,403 | +13,403 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 6,100 | 16,900 | +10,800 | 0.00 | 0.00 | +0.00 | buy |
| Ancora Advisors LLC | 50,000 | 60,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 3,850 | 7,100 | +3,250 | 0.00 | 0.00 | +0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 27,588 | 30,779 | +3,191 | 0.00 | 0.00 | -0.00 | buy |
| Ikarian Capital, LLC | 462,828 | 466,019 | +3,191 | 0.21 | 0.23 | +0.02 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 17,576 | 17,576 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RTW INVESTMENTS, LP | 3,256,102 | 3,256,102 | 0 | 0.08 | 0.09 | +0.00 | hold |
| Creative Planning | 13,080 | 13,080 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Beta Wealth Group, Inc. | 14,127 | 14,127 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Valeo Financial Advisors, LLC | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Qube Research & Technologies Ltd | 194 | 194 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Bleichroeder LP | 1,326,085 | 1,326,085 | 0 | 0.49 | 0.59 | +0.10 | hold |
| OLIVER LAGORE VANVALIN INVESTMENT GROUP | 100 | 100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Federation des caisses Desjardins du Quebec | 10,500 | 10,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GOLDMAN SACHS GROUP INC | 1,353,067 | 1,353,067 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SIMPLEX TRADING, LLC | 1,086 | 478 | -608 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 21,611 | 18,923 | -2,688 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 31,970 | 28,316 | -3,654 | 0.00 | 0.00 | -0.00 | sell |
| Clear Creek Financial Management, LLC | 31,750 | 25,000 | -6,750 | 0.01 | 0.01 | -0.00 | sell |
| Engineers Gate Manager LP | 13,135 | 0 | -13,135 | 0.00 | 0.00 | -0.00 | sell |
| Virtu Financial LLC | 18,686 | 0 | -18,686 | 0.00 | 0.00 | -0.00 | sell |
| BIT Capital GmbH | 20,000 | 0 | -20,000 | 0.00 | 0.00 | -0.00 | sell |
| GROUP ONE TRADING LLC | 20,762 | 0 | -20,762 | 0.00 | 0.00 | -0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 73,704 | 39,450 | -34,254 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 255,185 | 100 | -255,085 | 0.00 | 0.00 | -0.00 | sell |
| VR Adviser, LLC | 925,048 | 0 | -925,048 | 0.11 | 0.00 | -0.11 | sell |