| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 0 | 6,976,000 | +6,976,000 | 0.00 | 0.02 | +0.02 | buy |
| Propel Bio Management, LLC | 1,791,557 | 5,124,890 | +3,333,333 | 4.22 | 10.26 | +6.04 | buy |
| ORBIMED ADVISORS LLC | 0 | 3,221,828 | +3,221,828 | 0.00 | 0.15 | +0.15 | buy |
| MORGAN STANLEY | 820,421 | 2,969,067 | +2,148,646 | 0.00 | 0.00 | +0.00 | buy |
| Simplify Asset Management Inc. | 990,000 | 2,832,974 | +1,842,974 | 0.12 | 0.11 | -0.00 | buy |
| RTW INVESTMENTS, LP | 2,506,102 | 2,506,102 | 0 | 0.07 | 0.06 | -0.01 | hold |
| Pathstone Holdings, LLC | 0 | 1,000,000 | +1,000,000 | 0.00 | 0.01 | +0.01 | buy |
| SPHERA FUNDS MANAGEMENT LTD. | 0 | 820,000 | +820,000 | 0.00 | 0.39 | +0.39 | buy |
| TORONTO DOMINION BANK | 750,000 | 750,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Affinity Asset Advisors, LLC | 0 | 666,666 | +666,666 | 0.00 | 0.12 | +0.12 | buy |
| Boxer Capital Management, LLC | 0 | 666,666 | +666,666 | 0.00 | 0.42 | +0.42 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 666,551 | +666,551 | 0.00 | 0.00 | +0.00 | buy |
| Lion Point Capital, LP | 548,806 | 658,553 | +109,747 | 7.23 | 7.48 | +0.25 | buy |
| CITADEL ADVISORS LLC | 0 | 512,067 | +512,067 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 425,028 | +425,028 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 408,492 | +408,492 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 401,559 | +401,559 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 322,648 | 397,534 | +74,886 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 119,449 | 356,567 | +237,118 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 256,772 | +256,772 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 234,041 | +234,041 | 0.00 | 0.00 | +0.00 | buy |
| AMH Equity Ltd | 0 | 231,671 | +231,671 | 0.00 | 0.58 | +0.58 | buy |
| Quadrature Capital Ltd | 0 | 223,470 | +223,470 | 0.00 | 0.01 | +0.01 | buy |
| Aptus Capital Advisors, LLC | 0 | 210,200 | +210,200 | 0.00 | 0.00 | +0.00 | buy |
| GUARDIAN WEALTH ADVISORS, LLC / NC | 0 | 210,200 | +210,200 | 0.00 | 0.03 | +0.03 | buy |
| XTX Topco Ltd | 160,963 | 187,301 | +26,338 | 0.01 | 0.02 | +0.01 | buy |
| ROYAL BANK OF CANADA | 0 | 143,400 | +143,400 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 138,812 | +138,812 | 0.00 | 0.00 | +0.00 | buy |
| Valeo Financial Advisors, LLC | 130,699 | 130,699 | 0 | 0.01 | 0.01 | -0.00 | hold |
| GSA CAPITAL PARTNERS LLP | 0 | 78,747 | +78,747 | 0.00 | 0.01 | +0.01 | buy |
| Cascades Capital Asset Management, LLC | 67,135 | 77,335 | +10,200 | 0.07 | 0.07 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 17,958 | 74,022 | +56,064 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 66,920 | +66,920 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 53,001 | 39,258 | -13,743 | 0.00 | 0.00 | -0.00 | sell |
| Focus Partners Wealth | 36,000 | 36,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Federation des caisses Desjardins du Quebec | 13,000 | 29,781 | +16,781 | 0.00 | 0.00 | +0.00 | buy |
| RAYMOND JAMES FINANCIAL INC | 43,235 | 26,600 | -16,635 | 0.00 | 0.00 | -0.00 | sell |
| Safeguard Investment Advisory Group, LLC | 25,044 | 25,044 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Mariner, LLC | 11,000 | 25,000 | +14,000 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 23,410 | 23,410 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 18,246 | 22,220 | +3,974 | 0.00 | 0.00 | +0.00 | buy |
| Stephenson & Company, Inc. | 0 | 20,000 | +20,000 | 0.00 | 0.02 | +0.02 | buy |
| NATIONAL BANK OF CANADA /FI/ | 18,700 | 18,700 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Bay Rivers Group | 14,321 | 16,691 | +2,370 | 0.01 | 0.01 | +0.00 | buy |
| Beta Wealth Group, Inc. | 14,127 | 14,127 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Cambridge Investment Research Advisors, Inc. | 0 | 12,698 | +12,698 | 0.00 | 0.00 | +0.00 | buy |
| SAPIENT CAPITAL LLC | 0 | 12,200 | +12,200 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 11,000 | 11,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AQR CAPITAL MANAGEMENT LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| Ancora Advisors LLC | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Secure Asset Management, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| JOURNEY STRATEGIC WEALTH LLC | 15,000 | 10,000 | -5,000 | 0.00 | 0.00 | -0.00 | sell |
| Taylor Financial Group, Inc. | 10,000 | 10,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| CITIGROUP INC | 0 | 7,812 | +7,812 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 31,616 | 7,022 | -24,594 | 0.00 | 0.00 | -0.00 | sell |
| US BANCORP \DE\ | 3,200 | 3,200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Wealthspire Advisors, LLC | 0 | 1,129 | +1,129 | 0.00 | 0.00 | +0.00 | buy |
| Arax Advisory Partners | 0 | 1,077 | +1,077 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 6 | 6 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Virtu Financial LLC | 14,761 | 0 | -14,761 | 0.00 | 0.00 | -0.00 | sell |
| BML Capital Management, LLC | 1,136,091 | 0 | -1,136,091 | 1.69 | 0.00 | -1.69 | sell |
| Alta Fundamental Advisers LLC | 1,398,977 | 0 | -1,398,977 | 1.48 | 0.00 | -1.48 | sell |
| Walleye Capital LLC | 15,109 | 0 | -15,109 | 0.00 | 0.00 | -0.00 | sell |
| Bleichroeder LP | 500,000 | 0 | -500,000 | 0.24 | 0.00 | -0.24 | sell |
| Scientech Research LLC | 19,064 | 0 | -19,064 | 0.01 | 0.00 | -0.01 | sell |
| MERCER GLOBAL ADVISORS INC /ADV | 15,100 | 0 | -15,100 | 0.00 | 0.00 | -0.00 | sell |