| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Ikarian Capital, LLC | 77,616 | 601,703 | +524,087 | 0.07 | 0.49 | +0.42 | buy |
| ADAR1 Capital Management, LLC | 121,461 | 420,765 | +299,304 | 0.07 | 0.20 | +0.13 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 22,415 | 177,858 | +155,443 | 0.00 | 0.02 | +0.01 | buy |
| DIADEMA PARTNERS LP | 442,520 | 565,975 | +123,455 | 1.47 | 1.13 | -0.34 | buy |
| AdvisorShares Investments LLC | 99,810 | 159,114 | +59,304 | 0.06 | 0.07 | +0.02 | buy |
| STEMPOINT CAPITAL LP | 2,328,492 | 2,366,554 | +38,062 | 1.49 | 1.63 | +0.14 | buy |
| DIMENSIONAL FUND ADVISORS LP | 0 | 17,545 | +17,545 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 256,926 | 270,187 | +13,261 | 0.00 | 0.00 | -0.00 | buy |
| Cubist Systematic Strategies, LLC | 0 | 10,088 | +10,088 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 411,553 | 416,338 | +4,785 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 45,211 | 48,093 | +2,882 | 0.00 | 0.00 | -0.00 | buy |
| BLAIR WILLIAM & CO/IL | 98,466 | 100,866 | +2,400 | 0.00 | 0.00 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 30,002 | 31,063 | +1,061 | 0.00 | 0.00 | -0.00 | buy |
| Banque Transatlantique SA | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| HighTower Advisors, LLC | 20,828 | 20,828 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Almitas Capital LLC | 254,655 | 254,655 | 0 | 0.16 | 0.21 | +0.05 | hold |
| BML Capital Management, LLC | 150,000 | 150,000 | 0 | 0.27 | 0.30 | +0.03 | hold |
| Performa Ltd (US), LLC | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Commodore Capital LP | 1,575,000 | 1,575,000 | 0 | 0.34 | 0.29 | -0.05 | hold |
| TCG Crossover Management, LLC | 2,676,580 | 2,676,580 | 0 | 0.77 | 0.91 | +0.14 | hold |
| SBI Securities Co., Ltd. | 286 | 286 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SJS Investment Consulting Inc. | 100 | 100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Fairman Group, LLC | 29 | 29 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Persistent Asset Partners Ltd | 121,651 | 121,651 | 0 | 0.30 | 0.27 | -0.03 | hold |
| CITIGROUP INC | 3 | 3 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 23,302 | 23,302 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 96,858 | 96,858 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 473 | 471 | -2 | 0.00 | 0.00 | -0.00 | sell |
| MAI Capital Management | 609 | 576 | -33 | 0.00 | 0.00 | -0.00 | sell |
| Kestra Advisory Services, LLC | 20,116 | 20,033 | -83 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 2,593 | 2,402 | -191 | 0.00 | 0.00 | +0.00 | sell |
| JONES FINANCIAL COMPANIES LLLP | 280 | 80 | -200 | 0.00 | 0.00 | -0.00 | sell |
| BFSG, LLC | 1,000 | 0 | -1,000 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 12,032 | 10,732 | -1,300 | 0.00 | 0.00 | -0.00 | sell |
| Prosperity Wealth Management, Inc. | 29,250 | 27,600 | -1,650 | 0.04 | 0.03 | -0.00 | sell |
| CWM, LLC | 3,416 | 1,582 | -1,834 | 0.00 | 0.00 | -0.00 | sell |
| Nantahala Capital Management, LLC | 1,981,980 | 1,978,492 | -3,488 | 0.41 | 0.41 | +0.00 | sell |
| Caption Management, LLC | 4,460 | 0 | -4,460 | 0.00 | 0.00 | -0.00 | sell |
| R Squared Ltd | 8,610 | 0 | -8,610 | 0.02 | 0.00 | -0.02 | sell |
| OSAIC HOLDINGS, INC. | 11,430 | 0 | -11,430 | 0.00 | 0.00 | -0.00 | sell |
| SPHERA FUNDS MANAGEMENT LTD. | 808,550 | 790,550 | -18,000 | 0.44 | 0.49 | +0.05 | sell |
| Man Group plc | 18,338 | 0 | -18,338 | 0.00 | 0.00 | -0.00 | sell |
| JPMORGAN CHASE & CO | 772,244 | 750,876 | -21,368 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 137,334 | 112,507 | -24,827 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 38,732 | 0 | -38,732 | 0.00 | 0.00 | -0.00 | sell |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 41,804 | 0 | -41,804 | 0.01 | 0.00 | -0.01 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 83,700 | 24,800 | -58,900 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 2,020,351 | 1,960,172 | -60,179 | 0.00 | 0.00 | -0.00 | sell |
| GROUP ONE TRADING LLC | 97,727 | 5,569 | -92,158 | 0.01 | 0.00 | -0.01 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 95,906 | 0 | -95,906 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 107,744 | 0 | -107,744 | 0.00 | 0.00 | -0.00 | sell |
| UBS Group AG | 132,314 | 0 | -132,314 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 194,533 | 0 | -194,533 | 0.00 | 0.00 | -0.00 | sell |