| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| JPMORGAN CHASE & CO | 0 | 772,244 | +772,244 | 0.00 | 0.00 | +0.00 | buy |
| STEMPOINT CAPITAL LP | 1,846,792 | 2,328,492 | +481,700 | 1.47 | 1.49 | +0.02 | buy |
| Nantahala Capital Management, LLC | 1,517,696 | 1,981,980 | +464,284 | 0.38 | 0.41 | +0.02 | buy |
| Almitas Capital LLC | 0 | 254,655 | +254,655 | 0.00 | 0.16 | +0.16 | buy |
| VANGUARD GROUP INC | 1,793,166 | 2,020,351 | +227,185 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 0 | 132,314 | +132,314 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 97,727 | +97,727 | 0.00 | 0.01 | +0.01 | buy |
| Squarepoint Ops LLC | 27,575 | 107,744 | +80,169 | 0.00 | 0.00 | +0.00 | buy |
| Ikarian Capital, LLC | 0 | 77,616 | +77,616 | 0.00 | 0.07 | +0.07 | buy |
| TWO SIGMA INVESTMENTS, LP | 61,542 | 137,334 | +75,792 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 52,094 | 95,906 | +43,812 | 0.00 | 0.00 | +0.00 | buy |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 0 | 41,804 | +41,804 | 0.00 | 0.01 | +0.01 | buy |
| AdvisorShares Investments LLC | 67,780 | 99,810 | +32,030 | 0.04 | 0.06 | +0.02 | buy |
| Prosperity Wealth Management, Inc. | 0 | 29,250 | +29,250 | 0.00 | 0.04 | +0.04 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 22,415 | +22,415 | 0.00 | 0.00 | +0.00 | buy |
| Man Group plc | 0 | 18,338 | +18,338 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 176,261 | 194,533 | +18,272 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 25,337 | 38,732 | +13,395 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 12,032 | +12,032 | 0.00 | 0.00 | +0.00 | buy |
| OSAIC HOLDINGS, INC. | 0 | 11,430 | +11,430 | 0.00 | 0.00 | +0.00 | buy |
| BLAIR WILLIAM & CO/IL | 88,466 | 98,466 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 88,708 | 96,858 | +8,150 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 2,416 | 3,416 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| Performa Ltd (US), LLC | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 0 | 609 | +609 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 473 | +473 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 80 | 280 | +200 | 0.00 | 0.00 | +0.00 | buy |
| Kestra Advisory Services, LLC | 20,033 | 20,116 | +83 | 0.00 | 0.00 | -0.00 | buy |
| HighTower Advisors, LLC | 20,828 | 20,828 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SPHERA FUNDS MANAGEMENT LTD. | 808,550 | 808,550 | 0 | 0.40 | 0.44 | +0.04 | hold |
| BML Capital Management, LLC | 150,000 | 150,000 | 0 | 0.27 | 0.27 | +0.01 | hold |
| Caption Management, LLC | 4,460 | 4,460 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BFSG, LLC | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Commodore Capital LP | 1,575,000 | 1,575,000 | 0 | 0.30 | 0.34 | +0.04 | hold |
| TCG Crossover Management, LLC | 2,676,580 | 2,676,580 | 0 | 0.68 | 0.77 | +0.09 | hold |
| SJS Investment Consulting Inc. | 100 | 100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Fairman Group, LLC | 29 | 29 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 23,302 | 23,302 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Farther Finance Advisors, LLC | 81 | 0 | -81 | 0.00 | 0.00 | -0.00 | sell |
| AMERICAN CENTURY COMPANIES INC | 30,197 | 30,002 | -195 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 412,129 | 411,553 | -576 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 1,229 | 3 | -1,226 | 0.00 | 0.00 | -0.00 | sell |
| GEODE CAPITAL MANAGEMENT, LLC | 258,524 | 256,926 | -1,598 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 2,259 | 0 | -2,259 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 49,431 | 45,211 | -4,220 | 0.00 | 0.00 | -0.00 | sell |
| Virtu Financial LLC | 20,210 | 0 | -20,210 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 23,000 | 2,593 | -20,407 | 0.00 | 0.00 | -0.00 | sell |
| Valence8 US LP | 34,376 | 0 | -34,376 | 0.05 | 0.00 | -0.05 | sell |
| ADAR1 Capital Management, LLC | 163,078 | 121,461 | -41,617 | 0.08 | 0.07 | -0.01 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 190,600 | 83,700 | -106,900 | 0.00 | 0.00 | -0.00 | sell |
| CITADEL ADVISORS LLC | 321,885 | 0 | -321,885 | 0.00 | 0.00 | -0.00 | sell |
| GREAT POINT PARTNERS LLC | 674,075 | 0 | -674,075 | 0.61 | 0.00 | -0.61 | sell |
| BVF INC/IL | 2,000,000 | 0 | -2,000,000 | 0.18 | 0.00 | -0.18 | sell |