| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ADAR1 Capital Management, LLC | 113,062 | 623,575 | +510,513 | 0.04 | 0.03 | -0.01 | buy |
| LUMINUS MANAGEMENT LLC | 0 | 350,000 | +350,000 | 0.00 | 0.21 | +0.21 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 85,594 | 334,786 | +249,192 | 0.00 | 0.00 | -0.00 | buy |
| JANE STREET GROUP, LLC | 302,683 | 527,127 | +224,444 | 0.00 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 20,676 | 197,045 | +176,369 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 1,687,735 | 1,824,738 | +137,003 | 0.00 | 0.00 | -0.00 | buy |
| OMERS ADMINISTRATION Corp | 0 | 103,400 | +103,400 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 68,017 | 151,874 | +83,857 | 0.00 | 0.00 | -0.00 | buy |
| GROUP ONE TRADING LLC | 28,928 | 106,137 | +77,209 | 0.00 | 0.00 | -0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 76,172 | +76,172 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 60,139 | +60,139 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 298,280 | 352,836 | +54,556 | 0.00 | 0.00 | -0.00 | buy |
| AdvisorShares Investments LLC | 206,998 | 250,188 | +43,190 | 0.12 | 0.03 | -0.09 | buy |
| Virtu Financial LLC | 0 | 37,739 | +37,739 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 37,585 | +37,585 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 0 | 30,490 | +30,490 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 48,093 | 72,655 | +24,562 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 96,858 | 121,114 | +24,256 | 0.00 | 0.00 | -0.00 | buy |
| Lighthouse Investment Partners, LLC | 0 | 20,580 | +20,580 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 0 | 19,973 | +19,973 | 0.00 | 0.00 | +0.00 | buy |
| Caption Management, LLC | 0 | 16,770 | +16,770 | 0.00 | 0.00 | +0.00 | buy |
| OCCUDO QUANTITATIVE STRATEGIES LP | 42,704 | 59,038 | +16,334 | 0.02 | 0.00 | -0.02 | buy |
| StoneX Group Inc. | 0 | 13,349 | +13,349 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 10,883 | 21,736 | +10,853 | 0.00 | 0.00 | -0.00 | buy |
| DRW Securities, LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 8,564 | +8,564 | 0.00 | 0.00 | +0.00 | buy |
| Truvestments Capital LLC | 8,655 | 16,992 | +8,337 | 0.01 | 0.00 | -0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 41,072 | 48,770 | +7,698 | 0.00 | 0.00 | -0.00 | buy |
| Kestra Advisory Services, LLC | 20,033 | 26,033 | +6,000 | 0.00 | 0.00 | -0.00 | buy |
| MAI Capital Management | 526 | 526 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ORBIMED ADVISORS LLC | 3,060,000 | 3,060,000 | 0 | 0.26 | 0.04 | -0.22 | hold |
| Performa Ltd (US), LLC | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TCG Crossover Management, LLC | 2,676,580 | 2,676,580 | 0 | 0.47 | 0.06 | -0.41 | hold |
| Fairman Group, LLC | 29 | 29 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 23,302 | 23,302 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BARCLAYS PLC | 1 | 0 | -1 | 0.00 | 0.00 | -0.00 | sell |
| SBI Securities Co., Ltd. | 290 | 288 | -2 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 56 | 13 | -43 | 0.00 | 0.00 | -0.00 | sell |
| JONES FINANCIAL COMPANIES LLLP | 114 | 0 | -114 | 0.00 | 0.00 | -0.00 | sell |
| HighTower Advisors, LLC | 20,828 | 20,628 | -200 | 0.00 | 0.00 | -0.00 | sell |
| BlackRock, Inc. | 423,128 | 422,759 | -369 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 3,453 | 0 | -3,453 | 0.00 | 0.00 | -0.00 | sell |
| FNY Investment Advisers, LLC | 6,000 | 0 | -6,000 | 0.01 | 0.00 | -0.01 | sell |
| BLAIR WILLIAM & CO/IL | 12,573 | 0 | -12,573 | 0.00 | 0.00 | -0.00 | sell |
| Quadrature Capital Ltd | 15,752 | 0 | -15,752 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA ADVISERS, LP | 157,032 | 137,732 | -19,300 | 0.00 | 0.00 | -0.00 | sell |
| GSA CAPITAL PARTNERS LLP | 31,486 | 0 | -31,486 | 0.01 | 0.00 | -0.01 | sell |
| Persistent Asset Partners Ltd | 75,319 | 26,612 | -48,707 | 0.19 | 0.01 | -0.19 | sell |
| GOLDMAN SACHS GROUP INC | 60,152 | 0 | -60,152 | 0.00 | 0.00 | -0.00 | sell |
| BOOTHBAY FUND MANAGEMENT, LLC | 197,024 | 134,571 | -62,453 | 0.02 | 0.00 | -0.02 | sell |
| Walleye Capital LLC | 67,770 | 0 | -67,770 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 69,712 | 0 | -69,712 | 0.01 | 0.00 | -0.01 | sell |
| TWO SIGMA INVESTMENTS, LP | 289,409 | 195,570 | -93,839 | 0.00 | 0.00 | -0.00 | sell |
| Ikarian Capital, LLC | 620,869 | 519,077 | -101,792 | 0.45 | 0.04 | -0.40 | sell |
| CITADEL ADVISORS LLC | 122,062 | 0 | -122,062 | 0.00 | 0.00 | -0.00 | sell |
| BML Capital Management, LLC | 150,000 | 0 | -150,000 | 0.49 | 0.00 | -0.49 | sell |
| DIADEMA PARTNERS LP | 349,789 | 100,000 | -249,789 | 0.86 | 0.04 | -0.83 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 422,012 | 160,791 | -261,221 | 0.00 | 0.00 | -0.00 | sell |
| Almitas Capital LLC | 261,399 | 0 | -261,399 | 0.21 | 0.00 | -0.21 | sell |
| JPMORGAN CHASE & CO | 271,825 | 0 | -271,825 | 0.00 | 0.00 | -0.00 | sell |
| Soleus Capital Management, L.P. | 550,000 | 0 | -550,000 | 0.10 | 0.00 | -0.10 | sell |
| Commodore Capital LP | 1,575,000 | 0 | -1,575,000 | 0.27 | 0.00 | -0.27 | sell |
| STEMPOINT CAPITAL LP | 2,488,685 | 616,749 | -1,871,936 | 1.56 | 0.02 | -1.54 | sell |
| Nantahala Capital Management, LLC | 1,978,492 | 0 | -1,978,492 | 0.43 | 0.00 | -0.43 | sell |
| JANUS HENDERSON GROUP PLC | 4,165,767 | 0 | -4,165,767 | 0.01 | 0.00 | -0.01 | sell |