| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Affinity Asset Advisors, LLC | 0 | 989,490 | +989,490 | 0.00 | 1.94 | +1.94 | buy |
| Point72 Asset Management, L.P. | 0 | 487,275 | +487,275 | 0.00 | 0.02 | +0.02 | buy |
| Jain Global LLC | 0 | 202,433 | +202,433 | 0.00 | 0.05 | +0.05 | buy |
| FEDERATED HERMES, INC. | 1,635,380 | 1,765,516 | +130,136 | 0.04 | 0.08 | +0.04 | buy |
| MILLENNIUM MANAGEMENT LLC | 119,812 | 246,685 | +126,873 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 69,892 | 153,027 | +83,135 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 0 | 70,531 | +70,531 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 0 | 68,023 | +68,023 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 244,400 | 310,965 | +66,565 | 0.00 | 0.00 | +0.00 | buy |
| J. Goldman & Co LP | 0 | 60,800 | +60,800 | 0.00 | 0.06 | +0.06 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 52,914 | +52,914 | 0.00 | 0.00 | +0.00 | buy |
| 683 Capital Management, LLC | 0 | 40,000 | +40,000 | 0.00 | 0.09 | +0.09 | buy |
| Qube Research & Technologies Ltd | 0 | 32,187 | +32,187 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 31,808 | +31,808 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 0 | 24,824 | +24,824 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 820 | 24,111 | +23,291 | 0.00 | 0.00 | +0.00 | buy |
| JANUS HENDERSON GROUP PLC | 1,403,842 | 1,425,785 | +21,943 | 0.01 | 0.02 | +0.01 | buy |
| Quadrature Capital Ltd | 0 | 17,573 | +17,573 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 19,165 | 36,297 | +17,132 | 0.00 | 0.00 | +0.00 | buy |
| Hudson Bay Capital Management LP | 0 | 16,542 | +16,542 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 108,318 | 124,609 | +16,291 | 0.00 | 0.00 | +0.00 | buy |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 0 | 15,804 | +15,804 | 0.00 | 0.03 | +0.03 | buy |
| OMERS ADMINISTRATION Corp | 0 | 15,600 | +15,600 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 566,741 | 582,263 | +15,522 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 8 | 15,472 | +15,464 | 0.00 | 0.00 | +0.00 | buy |
| BlackRock, Inc. | 50,662 | 64,496 | +13,834 | 0.00 | 0.00 | +0.00 | buy |
| Trexquant Investment LP | 0 | 12,916 | +12,916 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 38,097 | 50,721 | +12,624 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 11,084 | +11,084 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 0 | 10,289 | +10,289 | 0.00 | 0.00 | +0.00 | buy |
| Persistent Asset Partners Ltd | 0 | 10,146 | +10,146 | 0.00 | 0.13 | +0.13 | buy |
| AMERICAN CENTURY COMPANIES INC | 0 | 8,085 | +8,085 | 0.00 | 0.00 | +0.00 | buy |
| AlphaQuest LLC | 12,291 | 18,804 | +6,513 | 0.01 | 0.03 | +0.02 | buy |
| SIMPLEX TRADING, LLC | 0 | 6,015 | +6,015 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 23,285 | 25,441 | +2,156 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 1,279 | +1,279 | 0.00 | 0.00 | +0.00 | buy |
| Global Retirement Partners, LLC | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 11,253 | 11,986 | +733 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 162 | 773 | +611 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 104 | 204 | +100 | 0.00 | 0.00 | +0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 0 | 76 | +76 | 0.00 | 0.00 | +0.00 | buy |
| Rockefeller Capital Management L.P. | 0 | 28 | +28 | 0.00 | 0.00 | +0.00 | buy |
| ORBIMED ADVISORS LLC | 1,196,955 | 1,196,955 | 0 | 0.43 | 0.67 | +0.24 | hold |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 333,333 | 333,333 | 0 | 0.01 | 0.01 | +0.01 | hold |
| Steward Partners Investment Advisory, LLC | 553 | 553 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Ikarian Capital, LLC | 300,000 | 300,000 | 0 | 0.91 | 1.06 | +0.15 | hold |
| Woodline Partners LP | 331,987 | 331,987 | 0 | 0.02 | 0.04 | +0.01 | hold |
| REAP Financial Group, LLC | 3 | 3 | 0 | 0.00 | 0.00 | +0.00 | hold |
| COMERICA BANK | 150 | 150 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SBI Securities Co., Ltd. | 13 | 12 | -1 | 0.00 | 0.00 | +0.00 | sell |
| ASSETMARK, INC | 81 | 58 | -23 | 0.00 | 0.00 | +0.00 | sell |
| PRIVATE TRUST CO NA | 274 | 0 | -274 | 0.00 | 0.00 | -0.00 | sell |
| ENVESTNET ASSET MANAGEMENT INC | 23,347 | 19,498 | -3,849 | 0.00 | 0.00 | +0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 10,765 | 0 | -10,765 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 16,200 | 0 | -16,200 | 0.00 | 0.00 | -0.00 | sell |
| AWM Investment Company, Inc. | 261,821 | 236,821 | -25,000 | 0.37 | 0.62 | +0.26 | sell |
| BVF INC/IL | 65,350 | 0 | -65,350 | 0.04 | 0.00 | -0.04 | sell |
| Mink Brook Asset Management LLC | 81,312 | 0 | -81,312 | 0.82 | 0.00 | -0.82 | sell |
| Cable Car Capital, LP | 500,000 | 400,000 | -100,000 | 3.21 | 0.68 | -2.54 | sell |
| FRED ALGER MANAGEMENT, LLC | 1,636,030 | 1,460,971 | -175,059 | 0.10 | 0.16 | +0.06 | sell |
| SPHERA FUNDS MANAGEMENT LTD. | 474,309 | 185,869 | -288,440 | 1.69 | 1.06 | -0.63 | sell |