| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| MILLENNIUM MANAGEMENT LLC | 348,274 | 421,629 | +73,355 | 0.00 | 0.00 | -0.00 | buy |
| NOTTINGHAM ADVISORS, INC. | 25,000 | 30,000 | +5,000 | 0.01 | 0.01 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 110 | +110 | 0.00 | 0.00 | 0.00 | buy |
| ORBIMED ADVISORS LLC | 2,133,405 | 2,133,405 | 0 | 0.12 | 0.09 | -0.03 | hold |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HOLLENCREST CAPITAL MANAGEMENT | 20,000 | 20,000 | 0 | 0.01 | 0.00 | -0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 18,244 | 18,244 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MARSHALL WACE, LLP | 1,860,405 | 1,860,405 | 0 | 0.01 | 0.01 | -0.00 | hold |
| AdvisorNet Financial, Inc | 8,783 | 8,783 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Mesirow Financial Investment Management, Inc. | 30,000 | 30,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Nantahala Capital Management, LLC | 2,066,456 | 2,066,456 | 0 | 0.58 | 0.48 | -0.10 | hold |
| McKinley Carter Wealth Services, Inc. | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PURA VIDA INVESTMENTS, LLC | 450,517 | 450,517 | 0 | 0.30 | 0.73 | +0.42 | hold |
| Avestar Capital, LLC | 20,000 | 20,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Global Retirement Partners, LLC | 27 | 27 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BELLEVUE ASSET MANAGEMENT, LLC | 19 | 19 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Soleus Capital Management, L.P. | 1,378,128 | 1,378,128 | 0 | 0.43 | 0.29 | -0.14 | hold |
| Velan Capital Investment Management LP | 904,029 | 904,029 | 0 | 1.80 | 1.16 | -0.64 | hold |
| NATIONAL BANK OF CANADA /FI/ | 206 | 206 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GROUP ONE TRADING LLC | 109 | 109 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Financial Perspectives, Inc | 1,101 | 0 | -1,101 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 15,000 | 12,400 | -2,600 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 28,438 | 25,190 | -3,248 | 0.00 | 0.00 | -0.00 | sell |
| HighTower Advisors, LLC | 27,262 | 0 | -27,262 | 0.00 | 0.00 | -0.00 | sell |
| Rosalind Advisors, Inc. | 925,194 | 686,062 | -239,132 | 2.18 | 1.52 | -0.65 | sell |