| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Rosalind Advisors, Inc. | 3,905,743 | 3,905,743 | 0 | 2.61 | 1.03 | -1.58 | hold |
| Aberdeen Group plc | 3,173,364 | 3,698,364 | +525,000 | 0.01 | 0.00 | -0.00 | buy |
| Nantahala Capital Management, LLC | 3,376,484 | 3,376,484 | 0 | 0.34 | 0.14 | -0.20 | hold |
| ORBIMED ADVISORS LLC | 3,133,405 | 3,133,405 | 0 | 0.11 | 0.04 | -0.07 | hold |
| Parkman Healthcare Partners LLC | 2,416,518 | 2,416,518 | 0 | 0.41 | 0.17 | -0.23 | hold |
| MARSHALL WACE, LLP | 1,860,405 | 1,860,405 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Soleus Capital Management, L.P. | 1,045,708 | 1,045,708 | 0 | 0.07 | 0.03 | -0.04 | hold |
| PURA VIDA INVESTMENTS, LLC | 450,517 | 450,517 | 0 | 4.94 | 0.85 | -4.08 | hold |
| INGALLS & SNYDER LLC | 379,300 | 368,800 | -10,500 | 0.02 | 0.01 | -0.01 | sell |
| Affiance Financial, LLC | 250,370 | 250,370 | 0 | 0.07 | 0.03 | -0.04 | hold |
| Velan Capital Investment Management LP | 2,099,652 | 148,138 | -1,951,514 | 2.14 | 0.06 | -2.08 | sell |
| BlackRock, Inc. | 80,449 | 122,993 | +42,544 | 0.00 | 0.00 | -0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 17,609 | 112,832 | +95,223 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 19,714 | 108,964 | +89,250 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 99,275 | +99,275 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 59,754 | +59,754 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 12,358 | 49,029 | +36,671 | 0.00 | 0.00 | +0.00 | buy |
| Centiva Capital, LP | 24,766 | 44,123 | +19,357 | 0.00 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 112,423 | 37,677 | -74,746 | 0.00 | 0.00 | -0.00 | sell |
| COURIER CAPITAL LLC | 30,000 | 30,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Mesirow Financial Investment Management, Inc. | 30,000 | 30,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| VESTIA PERSONAL WEALTH ADVISORS | 24,425 | 24,425 | 0 | 0.02 | 0.01 | -0.01 | hold |
| Cambridge Investment Research Advisors, Inc. | 0 | 20,166 | +20,166 | 0.00 | 0.00 | +0.00 | buy |
| Avestar Capital, LLC | 15,000 | 15,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Pallas Capital Advisors LLC | 13,000 | 11,000 | -2,000 | 0.00 | 0.00 | -0.00 | sell |
| McKinley Carter Wealth Services, Inc. | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AdvisorNet Financial, Inc | 8,783 | 8,783 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SIMPLEX TRADING, LLC | 603 | 745 | +142 | 0.00 | 0.00 | -0.00 | buy |
| Caitong International Asset Management Co., Ltd | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 18,244 | 0 | -18,244 | 0.00 | 0.00 | -0.00 | sell |
| Legato Capital Management LLC | 26,850 | 0 | -26,850 | 0.00 | 0.00 | -0.00 | sell |
| Global Retirement Partners, LLC | 27 | 0 | -27 | 0.00 | 0.00 | -0.00 | sell |
| Farther Finance Advisors, LLC | 1,000 | 0 | -1,000 | 0.00 | 0.00 | -0.00 | sell |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 114,085 | 0 | -114,085 | 0.03 | 0.00 | -0.03 | sell |
| NORTHERN TRUST CORP | 33,572 | 0 | -33,572 | 0.00 | 0.00 | -0.00 | sell |