| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Affiance Financial, LLC | 0 | 183,746 | +183,746 | 0.00 | 0.12 | +0.12 | buy |
| Nantahala Capital Management, LLC | 2,026,600 | 2,209,593 | +182,993 | 0.51 | 0.50 | -0.01 | buy |
| Parkman Healthcare Partners LLC | 0 | 104,081 | +104,081 | 0.00 | 0.04 | +0.04 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 11,900 | +11,900 | 0.00 | 0.00 | +0.00 | buy |
| BALDWIN WEALTH PARTNERS LLC/MA | 0 | 2,851 | +2,851 | 0.00 | 0.00 | +0.00 | buy |
| Rosalind Advisors, Inc. | 2,513,641 | 2,514,046 | +405 | 4.96 | 4.47 | -0.49 | buy |
| ORBIMED ADVISORS LLC | 2,133,405 | 2,133,405 | 0 | 0.11 | 0.10 | -0.00 | hold |
| NOTTINGHAM ADVISORS, INC. | 30,000 | 30,000 | 0 | 0.01 | 0.01 | +0.00 | hold |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HOLLENCREST CAPITAL MANAGEMENT | 20,000 | 20,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 18,244 | 18,244 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MARSHALL WACE, LLP | 1,860,405 | 1,860,405 | 0 | 0.01 | 0.01 | -0.00 | hold |
| AdvisorNet Financial, Inc | 8,783 | 8,783 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Mesirow Financial Investment Management, Inc. | 30,000 | 30,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| McKinley Carter Wealth Services, Inc. | 10,000 | 10,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PURA VIDA INVESTMENTS, LLC | 450,517 | 450,517 | 0 | 1.36 | 1.98 | +0.63 | hold |
| Global Retirement Partners, LLC | 27 | 27 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Soleus Capital Management, L.P. | 1,378,128 | 1,378,128 | 0 | 0.30 | 0.31 | +0.00 | hold |
| Velan Capital Investment Management LP | 904,029 | 904,029 | 0 | 1.29 | 2.63 | +1.34 | hold |
| Farther Finance Advisors, LLC | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NATIONAL BANK OF CANADA /FI/ | 206 | 206 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BELLEVUE ASSET MANAGEMENT, LLC | 19 | 15 | -4 | 0.00 | 0.00 | +0.00 | sell |
| NORTHERN TRUST CORP | 24,232 | 23,570 | -662 | 0.00 | 0.00 | +0.00 | sell |
| Avestar Capital, LLC | 20,000 | 15,000 | -5,000 | 0.01 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 10,800 | 0 | -10,800 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 421,725 | 399,818 | -21,907 | 0.00 | 0.00 | +0.00 | sell |