| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 1,768,050 | 2,066,456 | +298,406 | 0.73 | 0.58 | -0.15 | buy |
| ORBIMED ADVISORS LLC | 1,860,405 | 2,133,405 | +273,000 | 0.13 | 0.12 | -0.01 | buy |
| MILLENNIUM MANAGEMENT LLC | 205,826 | 348,274 | +142,448 | 0.00 | 0.00 | +0.00 | buy |
| PURA VIDA INVESTMENTS, LLC | 356,191 | 450,517 | +94,326 | 0.57 | 0.30 | -0.27 | buy |
| Mesirow Financial Investment Management, Inc. | 0 | 30,000 | +30,000 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 0 | 28,438 | +28,438 | 0.00 | 0.00 | +0.00 | buy |
| McKinley Carter Wealth Services, Inc. | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| HighTower Advisors, LLC | 26,762 | 27,262 | +500 | 0.00 | 0.00 | -0.00 | buy |
| BELLEVUE ASSET MANAGEMENT, LLC | 15 | 19 | +4 | 0.00 | 0.00 | +0.00 | buy |
| NOTTINGHAM ADVISORS, INC. | 25,000 | 25,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 1 | 1 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HOLLENCREST CAPITAL MANAGEMENT | 20,000 | 20,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 18,244 | 18,244 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MARSHALL WACE, LLP | 1,860,405 | 1,860,405 | 0 | 0.01 | 0.01 | -0.00 | hold |
| AdvisorNet Financial, Inc | 8,783 | 8,783 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Avestar Capital, LLC | 20,000 | 20,000 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Global Retirement Partners, LLC | 27 | 27 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Soleus Capital Management, L.P. | 1,378,128 | 1,378,128 | 0 | 0.45 | 0.43 | -0.02 | hold |
| Velan Capital Investment Management LP | 904,029 | 904,029 | 0 | 2.42 | 1.80 | -0.62 | hold |
| Financial Perspectives, Inc | 1,101 | 1,101 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NATIONAL BANK OF CANADA /FI/ | 206 | 206 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GROUP ONE TRADING LLC | 109 | 109 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RENAISSANCE TECHNOLOGIES LLC | 16,700 | 15,000 | -1,700 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 1,782 | 0 | -1,782 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 24,716 | 0 | -24,716 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asset Management, L.P. | 219,093 | 0 | -219,093 | 0.00 | 0.00 | -0.00 | sell |