| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Redmile Group, LLC | 12,872,946 | 12,872,946 | 0 | 0.96 | 1.53 | +0.57 | hold |
| BlackRock, Inc. | 10,681,779 | 10,810,481 | +128,702 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 10,310,453 | 8,766,764 | -1,543,689 | 0.00 | 0.00 | +0.00 | sell |
| CITADEL ADVISORS LLC | 4,289,159 | 4,543,867 | +254,708 | 0.00 | 0.00 | +0.00 | buy |
| JOHNSON & JOHNSON | 3,379,064 | 3,379,064 | 0 | 0.78 | 1.05 | +0.27 | hold |
| Vestal Point Capital, LP | 2,515,850 | 2,515,000 | -850 | 0.14 | 0.15 | +0.01 | sell |
| GOLDMAN SACHS GROUP INC | 2,458,974 | 2,511,676 | +52,702 | 0.00 | 0.00 | +0.00 | buy |
| BAKER BROS. ADVISORS LP | 3,258,402 | 2,485,018 | -773,384 | 0.03 | 0.03 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 2,473,565 | 2,459,954 | -13,611 | 0.01 | 0.01 | +0.00 | sell |
| DIMENSIONAL FUND ADVISORS LP | 2,591,558 | 2,437,729 | -153,829 | 0.00 | 0.00 | +0.00 | sell |
| MORGAN STANLEY | 2,240,058 | 2,433,575 | +193,517 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 2,269,609 | 2,429,167 | +159,558 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 2,110,065 | 2,229,121 | +119,056 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 1,937,133 | 1,903,738 | -33,395 | 0.00 | 0.00 | +0.00 | sell |
| TANG CAPITAL MANAGEMENT LLC | 1,867,773 | 1,867,773 | 0 | 0.08 | 0.11 | +0.02 | hold |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 2,203,323 | 1,213,736 | -989,587 | 0.01 | 0.01 | -0.00 | sell |
| UBS Group AG | 1,551,081 | 962,672 | -588,409 | 0.00 | 0.00 | -0.00 | sell |
| Schonfeld Strategic Advisors LLC | 7,794,513 | 930,809 | -6,863,704 | 0.04 | 0.01 | -0.03 | sell |
| MILLENNIUM MANAGEMENT LLC | 314,877 | 879,688 | +564,811 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 585,025 | 846,233 | +261,208 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 794,973 | 844,350 | +49,377 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 703,825 | 733,911 | +30,086 | 0.00 | 0.00 | +0.00 | buy |
| Woodline Partners LP | 1,424,167 | 712,650 | -711,517 | 0.01 | 0.00 | -0.00 | sell |
| Monaco Asset Management SAM | 1,149,708 | 675,000 | -474,708 | 0.46 | 0.29 | -0.17 | sell |
| TWO SIGMA ADVISERS, LP | 787,000 | 493,100 | -293,900 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 0 | 465,820 | +465,820 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 367,285 | 453,072 | +85,787 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 459,308 | 432,328 | -26,980 | 0.02 | 0.02 | +0.00 | sell |
| Bruce & Co., Inc. | 550,000 | 429,188 | -120,812 | 0.14 | 0.16 | +0.02 | sell |
| AMERIPRISE FINANCIAL INC | 411,332 | 339,714 | -71,618 | 0.00 | 0.00 | +0.00 | sell |
| Nuveen, LLC | 379,088 | 336,872 | -42,216 | 0.00 | 0.00 | +0.00 | sell |
| Bank of New York Mellon Corp | 291,755 | 290,652 | -1,103 | 0.00 | 0.00 | +0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 289,232 | +289,232 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 342,236 | 287,412 | -54,824 | 0.00 | 0.00 | +0.00 | sell |
| GSA CAPITAL PARTNERS LLP | 0 | 256,722 | +256,722 | 0.00 | 0.02 | +0.02 | buy |
| Invesco Ltd. | 213,503 | 255,372 | +41,869 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 241,872 | 228,405 | -13,467 | 0.00 | 0.00 | +0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 214,463 | +214,463 | 0.00 | 0.00 | +0.00 | buy |
| Assenagon Asset Management S.A. | 302,899 | 212,342 | -90,557 | 0.00 | 0.00 | -0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 146,580 | 187,700 | +41,120 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 150,248 | 155,858 | +5,610 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 0 | 149,952 | +149,952 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 102,938 | 122,192 | +19,254 | 0.00 | 0.00 | +0.00 | buy |
| IEQ CAPITAL, LLC | 74,506 | 117,057 | +42,551 | 0.00 | 0.00 | +0.00 | buy |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 162,655 | 113,655 | -49,000 | 0.00 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 0 | 111,512 | +111,512 | 0.00 | 0.00 | +0.00 | buy |
| Privium Fund Management B.V. | 109,026 | 111,090 | +2,064 | 0.02 | 0.03 | +0.00 | buy |
| HSBC HOLDINGS PLC | 109,346 | 102,966 | -6,380 | 0.00 | 0.00 | +0.00 | sell |
| Virtu Financial LLC | 0 | 100,879 | +100,879 | 0.00 | 0.01 | +0.01 | buy |
| Graham Capital Management, L.P. | 140,064 | 85,633 | -54,431 | 0.00 | 0.00 | -0.00 | sell |
| INTECH INVESTMENT MANAGEMENT LLC | 78,383 | 73,379 | -5,004 | 0.00 | 0.00 | +0.00 | sell |
| Vanguard Personalized Indexing Management, LLC | 43,096 | 71,364 | +28,268 | 0.00 | 0.00 | +0.00 | buy |
| Leo Wealth, LLC | 70,439 | 70,439 | 0 | 0.01 | 0.01 | -0.00 | hold |
| MetLife Investment Management, LLC | 0 | 67,990 | +67,990 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 67,843 | 67,721 | -122 | 0.00 | 0.00 | +0.00 | sell |
| JPMORGAN CHASE & CO | 3,398,283 | 58,574 | -3,339,709 | 0.00 | 0.00 | -0.00 | sell |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 59,861 | 57,321 | -2,540 | 0.00 | 0.00 | +0.00 | sell |
| SG Americas Securities, LLC | 34,502 | 52,602 | +18,100 | 0.00 | 0.00 | +0.00 | buy |
| Headlands Technologies LLC | 0 | 49,556 | +49,556 | 0.00 | 0.01 | +0.01 | buy |
| CWM, LLC | 41,435 | 49,438 | +8,003 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 38,049 | 46,855 | +8,806 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 37,096 | 41,134 | +4,038 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 14,380 | 38,019 | +23,639 | 0.00 | 0.00 | +0.00 | buy |
| HighTower Advisors, LLC | 10,200 | 37,200 | +27,000 | 0.00 | 0.00 | +0.00 | buy |
| THRIVENT FINANCIAL FOR LUTHERANS | 89,322 | 37,116 | -52,206 | 0.00 | 0.00 | -0.00 | sell |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 29,909 | 35,347 | +5,438 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 57,897 | 34,063 | -23,834 | 0.00 | 0.00 | -0.00 | sell |
| Focus Partners Wealth | 30,201 | 32,716 | +2,515 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 29,676 | 32,139 | +2,463 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 29,904 | 31,007 | +1,103 | 0.00 | 0.00 | +0.00 | buy |
| Parcion Private Wealth LLC | 30,393 | 30,785 | +392 | 0.00 | 0.00 | +0.00 | buy |
| Corient Private Wealth LLC | 29,649 | 29,724 | +75 | 0.00 | 0.00 | +0.00 | buy |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 28,016 | 28,016 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 28,015 | 28,015 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ProShare Advisors LLC | 26,811 | 26,640 | -171 | 0.00 | 0.00 | +0.00 | sell |
| FPC INVESTMENT ADVISORY, INC. | 26,456 | 26,456 | 0 | 0.02 | 0.02 | -0.00 | hold |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 0 | 25,000 | +25,000 | 0.00 | 0.00 | +0.00 | buy |
| Savant Capital, LLC | 0 | 24,205 | +24,205 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 16,886 | 23,758 | +6,872 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 22,845 | 23,024 | +179 | 0.00 | 0.00 | +0.00 | buy |
| CANADA LIFE ASSURANCE Co | 20,401 | 22,796 | +2,395 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 73,291 | 21,791 | -51,500 | 0.00 | 0.00 | -0.00 | sell |
| Police & Firemen's Retirement System of New Jersey | 20,768 | 20,768 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Quinn Opportunity Partners LLC | 0 | 20,000 | +20,000 | 0.00 | 0.00 | +0.00 | buy |
| CAPTRUST FINANCIAL ADVISORS | 16,429 | 19,604 | +3,175 | 0.00 | 0.00 | +0.00 | buy |
| TITLEIST ASSET MANAGEMENT, LLC | 0 | 19,000 | +19,000 | 0.00 | 0.00 | +0.00 | buy |
| Parametrica Management Ltd | 18,472 | 18,472 | 0 | 0.02 | 0.04 | +0.01 | hold |
| Grassi Investment Management | 18,000 | 18,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Squarepoint Ops LLC | 0 | 17,759 | +17,759 | 0.00 | 0.00 | +0.00 | buy |
| TIAA TRUST, NATIONAL ASSOCIATION | 17,592 | 17,592 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Russell Investments Group, Ltd. | 79,377 | 16,562 | -62,815 | 0.00 | 0.00 | -0.00 | sell |
| Pallas Capital Advisors LLC | 14,232 | 15,336 | +1,104 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 22,214 | 13,400 | -8,814 | 0.00 | 0.00 | -0.00 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 11,872 | 12,770 | +898 | 0.00 | 0.00 | -0.00 | buy |
| Narwhal Capital Management | 0 | 12,700 | +12,700 | 0.00 | 0.00 | +0.00 | buy |
| HBK Sorce Advisory LLC | 0 | 12,129 | +12,129 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 0 | 11,537 | +11,537 | 0.00 | 0.00 | +0.00 | buy |
| Point72 (DIFC) Ltd | 0 | 10,465 | +10,465 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 8,644 | 10,398 | +1,754 | 0.00 | 0.00 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 10,197 | 10,197 | 0 | 0.00 | 0.00 | +0.00 | hold |