| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Woodline Partners LP | 4,615,625 | 4,615,676 | +51 | 0.22 | 0.21 | -0.01 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 3,618,000 | 4,168,000 | +550,000 | 0.05 | 0.06 | +0.01 | buy |
| BlackRock, Inc. | 4,126,563 | 4,081,544 | -45,019 | 0.00 | 0.00 | +0.00 | sell |
| VANGUARD GROUP INC | 2,825,845 | 2,952,686 | +126,841 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 2,306,317 | 2,289,243 | -17,074 | 0.00 | 0.00 | +0.00 | sell |
| Rubric Capital Management LP | 1,217,734 | 1,958,318 | +740,584 | 0.16 | 0.28 | +0.11 | buy |
| Nantahala Capital Management, LLC | 1,471,936 | 1,471,936 | 0 | 0.91 | 0.92 | +0.01 | hold |
| GEODE CAPITAL MANAGEMENT, LLC | 1,233,111 | 1,242,386 | +9,275 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 1,176,548 | 1,241,658 | +65,110 | 0.00 | 0.00 | +0.00 | buy |
| 683 Capital Management, LLC | 1,225,834 | 1,125,000 | -100,834 | 0.93 | 1.01 | +0.07 | sell |
| Legal & General Group Plc | 737,737 | 935,677 | +197,940 | 0.00 | 0.00 | +0.00 | buy |
| AIGH Capital Management LLC | 1,438,109 | 918,893 | -519,216 | 5.59 | 3.80 | -1.79 | sell |
| Stonepine Capital Management, LLC | 650,000 | 775,620 | +125,620 | 4.74 | 6.73 | +1.99 | buy |
| Velan Capital Investment Management LP | 665,000 | 715,000 | +50,000 | 5.12 | 6.30 | +1.18 | buy |
| MILLENNIUM MANAGEMENT LLC | 108,701 | 634,820 | +526,119 | 0.00 | 0.01 | +0.00 | buy |
| Retirement Planning Co of New England, Inc. | 550,180 | 553,297 | +3,117 | 2.05 | 2.17 | +0.12 | buy |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | 0 | 450,000 | +450,000 | 0.00 | 0.77 | +0.77 | buy |
| NORTHERN TRUST CORP | 429,111 | 425,119 | -3,992 | 0.00 | 0.00 | +0.00 | sell |
| GOLDMAN SACHS GROUP INC | 194,813 | 374,792 | +179,979 | 0.00 | 0.00 | +0.00 | buy |
| Mystic Asset Management, Inc. | 338,902 | 346,652 | +7,750 | 0.67 | 0.74 | +0.07 | buy |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 0 | 315,469 | +315,469 | 0.00 | 0.00 | +0.00 | buy |
| Janney Montgomery Scott LLC | 280,534 | 256,664 | -23,870 | 0.01 | 0.01 | -0.00 | sell |
| Propel Bio Management, LLC | 179,874 | 231,874 | +52,000 | 1.57 | 2.48 | +0.91 | buy |
| BANK OF AMERICA CORP /DE/ | 89,415 | 223,852 | +134,437 | 0.00 | 0.00 | +0.00 | buy |
| Stratos Wealth Partners, LTD. | 310,000 | 220,000 | -90,000 | 0.04 | 0.03 | -0.01 | sell |
| MORGAN STANLEY | 211,848 | 213,088 | +1,240 | 0.00 | 0.00 | +0.00 | buy |
| D. E. Shaw & Co., Inc. | 27,370 | 189,313 | +161,943 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 153,331 | 161,967 | +8,636 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 165,415 | 161,493 | -3,922 | 0.00 | 0.00 | +0.00 | sell |
| UBS Group AG | 163,064 | 154,184 | -8,880 | 0.00 | 0.00 | +0.00 | sell |
| JANE STREET GROUP, LLC | 0 | 148,904 | +148,904 | 0.00 | 0.00 | +0.00 | buy |
| Simplify Asset Management Inc. | 120,000 | 147,000 | +27,000 | 0.04 | 0.08 | +0.04 | buy |
| Kovack Advisors, Inc. | 146,747 | 146,788 | +41 | 0.12 | 0.13 | +0.01 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 140,418 | 146,284 | +5,866 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 97,530 | 143,132 | +45,602 | 0.00 | 0.00 | -0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 0 | 121,225 | +121,225 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 120,433 | 118,975 | -1,458 | 0.00 | 0.00 | +0.00 | sell |
| ROYAL BANK OF CANADA | 0 | 118,237 | +118,237 | 0.00 | 0.00 | +0.00 | buy |
| CITADEL ADVISORS LLC | 248,832 | 114,267 | -134,565 | 0.00 | 0.00 | -0.00 | sell |
| READYSTATE ASSET MANAGEMENT LP | 683,032 | 111,515 | -571,517 | 0.26 | 0.04 | -0.22 | sell |
| J. Goldman & Co LP | 489,647 | 108,000 | -381,647 | 0.13 | 0.03 | -0.10 | sell |
| BARCLAYS PLC | 434,690 | 104,351 | -330,339 | 0.00 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 0 | 88,414 | +88,414 | 0.00 | 0.01 | +0.01 | buy |
| Campbell & CO Investment Adviser LLC | 0 | 83,245 | +83,245 | 0.00 | 0.05 | +0.05 | buy |
| RHUMBLINE ADVISERS | 74,585 | 83,221 | +8,636 | 0.00 | 0.00 | +0.00 | buy |
| Arete Wealth Advisors, LLC | 74,854 | 74,789 | -65 | 0.04 | 0.05 | +0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 16,100 | 70,300 | +54,200 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 44,121 | 60,134 | +16,013 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 3,204 | 42,950 | +39,746 | 0.00 | 0.00 | +0.00 | buy |
| CARRET ASSET MANAGEMENT, LLC | 36,140 | 39,640 | +3,500 | 0.03 | 0.04 | +0.01 | buy |
| DEUTSCHE BANK AG\ | 45,681 | 38,470 | -7,211 | 0.00 | 0.00 | -0.00 | sell |
| MetLife Investment Management, LLC | 32,682 | 32,682 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Aquatic Capital Management LLC | 20,998 | 32,298 | +11,300 | 0.00 | 0.01 | +0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 30,436 | 31,334 | +898 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 31,761 | 30,260 | -1,501 | 0.00 | 0.00 | +0.00 | sell |
| WELLS FARGO & COMPANY/MN | 30,734 | 29,853 | -881 | 0.00 | 0.00 | +0.00 | sell |
| IFG Advisors, LLC | 29,050 | 29,050 | 0 | 0.04 | 0.04 | +0.00 | hold |
| Quantbot Technologies LP | 0 | 28,992 | +28,992 | 0.00 | 0.01 | +0.01 | buy |
| JPMORGAN CHASE & CO | 29,138 | 28,161 | -977 | 0.00 | 0.00 | +0.00 | sell |
| RAYMOND JAMES FINANCIAL INC | 26,916 | 26,916 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PRICE T ROWE ASSOCIATES INC /MD/ | 22,685 | 25,690 | +3,005 | 0.00 | 0.00 | +0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 25,592 | 25,592 | 0 | 0.00 | 0.00 | +0.00 | hold |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 18,544 | 20,294 | +1,750 | 0.00 | 0.00 | +0.00 | buy |
| CANTOR FITZGERALD, L. P. | 0 | 20,001 | +20,001 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 19,022 | 19,744 | +722 | 0.00 | 0.00 | +0.00 | buy |
| Corton Capital Inc. | 0 | 17,671 | +17,671 | 0.00 | 0.18 | +0.18 | buy |
| Polymer Capital Management (US) LLC | 0 | 16,732 | +16,732 | 0.00 | 0.02 | +0.02 | buy |
| City State Bank | 16,224 | 16,224 | 0 | 0.04 | 0.04 | +0.00 | hold |
| VOYA INVESTMENT MANAGEMENT LLC | 14,822 | 15,686 | +864 | 0.00 | 0.00 | +0.00 | buy |
| AXQ CAPITAL, LP | 0 | 15,317 | +15,317 | 0.00 | 0.04 | +0.04 | buy |
| OCCUDO QUANTITATIVE STRATEGIES LP | 0 | 14,138 | +14,138 | 0.00 | 0.01 | +0.01 | buy |
| HUNTER ASSOCIATES INVESTMENT MANAGEMENT LLC | 13,260 | 13,260 | 0 | 0.02 | 0.02 | +0.00 | hold |
| ProShare Advisors LLC | 14,022 | 13,171 | -851 | 0.00 | 0.00 | -0.00 | sell |
| SHERBROOKE PARK ADVISERS LLC | 0 | 12,217 | +12,217 | 0.00 | 0.05 | +0.05 | buy |
| Kingsview Wealth Management, LLC | 12,120 | 12,120 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Police & Firemen's Retirement System of New Jersey | 11,293 | 11,293 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Qube Research & Technologies Ltd | 0 | 11,288 | +11,288 | 0.00 | 0.00 | +0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 11,251 | +11,251 | 0.00 | 0.02 | +0.02 | buy |
| China Universal Asset Management Co., Ltd. | 10,706 | 10,982 | +276 | 0.01 | 0.01 | +0.00 | buy |
| Quantinno Capital Management LP | 0 | 10,478 | +10,478 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 0 | 10,453 | +10,453 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 10,107 | 10,107 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Tower Research Capital LLC (TRC) | 1,385 | 9,937 | +8,552 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 4,261 | 5,541 | +1,280 | 0.00 | 0.00 | +0.00 | buy |
| NewEdge Advisors, LLC | 4,000 | 4,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,895 | 3,895 | 0 | 0.00 | 0.00 | +0.00 | hold |
| LAZARD ASSET MANAGEMENT LLC | 0 | 2,959 | +2,959 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 1,786 | 2,112 | +326 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 109 | 1,899 | +1,790 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 1,825 | 1,825 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Activest Wealth Management | 1,815 | 1,815 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Vermillion Wealth Management, Inc. | 1,500 | 1,500 | 0 | 0.00 | 0.01 | +0.00 | hold |
| GF FUND MANAGEMENT CO. LTD. | 1,367 | 1,367 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 1,464 | 1,319 | -145 | 0.00 | 0.00 | -0.00 | sell |
| US BANCORP \DE\ | 1,013 | 1,055 | +42 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 211 | 852 | +641 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 0 | 824 | +824 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 485 | 575 | +90 | 0.00 | 0.00 | +0.00 | buy |
| Caitong International Asset Management Co., Ltd | 595 | 518 | -77 | 0.00 | 0.00 | -0.00 | sell |
| Binnacle Investments Inc | 648 | 461 | -187 | 0.00 | 0.00 | -0.00 | sell |