| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 649,000 | 3,650,000 | +3,001,000 | 0.01 | 0.05 | +0.05 | buy |
| Rubric Capital Management LP | 20,000 | 616,123 | +596,123 | 0.00 | 0.07 | +0.06 | buy |
| Altium Capital Management LLC | 1,700,000 | 1,850,000 | +150,000 | 3.51 | 4.81 | +1.29 | buy |
| Velan Capital Investment Management LP | 200,000 | 300,000 | +100,000 | 1.51 | 2.16 | +0.65 | buy |
| Woodline Partners LP | 4,048,653 | 4,139,593 | +90,940 | 0.24 | 0.23 | -0.00 | buy |
| LMR Partners LLP | 50,000 | 100,000 | +50,000 | 0.01 | 0.01 | +0.01 | buy |
| Retirement Planning Co of New England, Inc. | 499,505 | 514,832 | +15,327 | 1.73 | 2.08 | +0.36 | buy |
| Mystic Asset Management, Inc. | 307,447 | 313,347 | +5,900 | 0.81 | 0.70 | -0.10 | buy |
| IFG Advisors, LLC | 26,400 | 29,050 | +2,650 | 0.04 | 0.05 | +0.01 | buy |
| 683 Capital Management, LLC | 1,225,000 | 1,225,834 | +834 | 0.65 | 0.63 | -0.01 | buy |
| Kovack Advisors, Inc. | 148,802 | 146,158 | -2,644 | 0.11 | 0.12 | +0.01 | sell |
| Stonepine Capital Management, LLC | 700,000 | 597,700 | -102,300 | 3.07 | 4.02 | +0.95 | sell |
| J. Goldman & Co LP | 984,182 | 875,815 | -108,367 | 0.19 | 0.19 | -0.00 | sell |
| Nantahala Capital Management, LLC | 2,924,021 | 2,340,333 | -583,688 | 1.03 | 0.84 | -0.19 | sell |