| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Graham Capital Management, L.P. | 0 | 41,667,000 | +41,667,000 | 0.66 | 1.21 | +0.55 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 0 | 2,706,000 | +2,706,000 | 0.00 | 0.00 | +0.00 | buy |
| JANUS HENDERSON GROUP PLC | 7,528,622 | 9,541,270 | +2,012,648 | 0.08 | 0.07 | -0.01 | buy |
| Frazier Life Sciences Management, L.P. | 0 | 1,002,092 | +1,002,092 | 0.00 | 0.59 | +0.59 | buy |
| JANUS HENDERSON GROUP PLC | 10,394,000 | 11,391,000 | +997,000 | 0.01 | 0.01 | -0.00 | buy |
| VANGUARD GROUP INC | 5,014,020 | 5,994,283 | +980,263 | 0.00 | 0.00 | -0.00 | buy |
| PERCEPTIVE ADVISORS LLC | 0 | 834,252 | +834,252 | 0.00 | 0.46 | +0.46 | buy |
| MARSHALL WACE, LLP | 0 | 742,725 | +742,725 | 0.00 | 0.01 | +0.01 | buy |
| TANG CAPITAL MANAGEMENT LLC | 0 | 700,000 | +700,000 | 0.00 | 0.52 | +0.52 | buy |
| Cubist Systematic Strategies, LLC | 0 | 699,182 | +699,182 | 0.00 | 0.11 | +0.11 | buy |
| Assenagon Asset Management S.A. | 413,514 | 1,103,075 | +689,561 | 0.01 | 0.03 | +0.01 | buy |
| GOLDMAN SACHS GROUP INC | 867,642 | 1,556,852 | +689,210 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 945,906 | 1,621,393 | +675,487 | 0.00 | 0.00 | +0.00 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2,184,898 | 2,784,000 | +599,102 | 0.07 | 0.07 | -0.00 | buy |
| Eversept Partners, LP | 816,254 | 1,315,033 | +498,779 | 1.66 | 1.96 | +0.31 | buy |
| Aberdeen Group plc | 480,369 | 896,594 | +416,225 | 0.02 | 0.02 | +0.01 | buy |
| ROYCE & ASSOCIATES LP | 0 | 380,997 | +380,997 | 0.00 | 0.06 | +0.06 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 66,597 | 445,557 | +378,960 | 0.00 | 0.00 | +0.00 | buy |
| Ensign Peak Advisors, Inc | 498,734 | 858,834 | +360,100 | 0.02 | 0.02 | +0.00 | buy |
| Vestal Point Capital, LP | 0 | 355,000 | +355,000 | 0.00 | 0.28 | +0.28 | buy |
| Qube Research & Technologies Ltd | 292,991 | 604,128 | +311,137 | 0.01 | 0.01 | +0.00 | buy |
| MACQUARIE GROUP LTD | 4,797,314 | 5,097,482 | +300,168 | 0.11 | 0.09 | -0.01 | buy |
| Squarepoint Ops LLC | 217,024 | 479,394 | +262,370 | 0.01 | 0.02 | +0.01 | buy |
| FIRST TRUST ADVISORS LP | 0 | 239,045 | +239,045 | 0.00 | 0.00 | +0.00 | buy |
| Connor, Clark & Lunn Investment Management Ltd. | 495,177 | 685,511 | +190,334 | 0.04 | 0.04 | -0.00 | buy |
| CITADEL ADVISORS LLC | 524,335 | 711,257 | +186,922 | 0.01 | 0.01 | -0.00 | buy |
| Impax Asset Management Group plc | 300,000 | 475,000 | +175,000 | 0.03 | 0.04 | +0.01 | buy |
| HUSSMAN STRATEGIC ADVISORS, INC. | 0 | 168,000 | +168,000 | 0.00 | 0.57 | +0.57 | buy |
| Point72 Asset Management, L.P. | 0 | 167,896 | +167,896 | 0.00 | 0.01 | +0.01 | buy |
| Hillsdale Investment Management Inc. | 0 | 163,400 | +163,400 | 0.00 | 0.09 | +0.09 | buy |
| JPMORGAN CHASE & CO | 615,295 | 771,830 | +156,535 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 768,794 | 918,713 | +149,919 | 0.03 | 0.02 | -0.01 | buy |
| MILLENNIUM MANAGEMENT LLC | 59,832 | 208,991 | +149,159 | 0.00 | 0.00 | +0.00 | buy |
| SPHERA FUNDS MANAGEMENT LTD. | 200,000 | 335,333 | +135,333 | 0.88 | 1.30 | +0.41 | buy |
| ExodusPoint Capital Management, LP | 0 | 128,157 | +128,157 | 0.00 | 0.02 | +0.02 | buy |
| ALGERT GLOBAL LLC | 16,167 | 127,188 | +111,021 | 0.01 | 0.04 | +0.03 | buy |
| Exome Asset Management LLC | 0 | 110,000 | +110,000 | 0.00 | 1.34 | +1.34 | buy |
| CAPITAL FUND MANAGEMENT S.A. | 0 | 101,406 | +101,406 | 0.00 | 0.02 | +0.02 | buy |
| Legal & General Group Plc | 412,932 | 510,428 | +97,496 | 0.00 | 0.00 | -0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 335,959 | 432,021 | +96,062 | 0.03 | 0.03 | -0.00 | buy |
| Man Group plc | 48,779 | 139,044 | +90,265 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 88,195 | +88,195 | 0.00 | 0.09 | +0.09 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 684,543 | 771,296 | +86,753 | 0.00 | 0.00 | -0.00 | buy |
| MACKENZIE FINANCIAL CORP | 0 | 60,303 | +60,303 | 0.00 | 0.00 | +0.00 | buy |
| Y-Intercept (Hong Kong) Ltd | 15,325 | 68,000 | +52,675 | 0.02 | 0.02 | +0.01 | buy |
| ALPS ADVISORS INC | 0 | 47,948 | +47,948 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 32,412 | 80,142 | +47,730 | 0.00 | 0.00 | +0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 122,909 | 167,721 | +44,812 | 0.00 | 0.00 | +0.00 | buy |
| DARK FOREST CAPITAL MANAGEMENT LP | 10,791 | 53,258 | +42,467 | 0.01 | 0.03 | +0.02 | buy |
| F/m Investments LLC | 147,465 | 187,734 | +40,269 | 0.11 | 0.10 | -0.00 | buy |
| PDT Partners, LLC | 309,534 | 349,577 | +40,043 | 0.39 | 0.29 | -0.10 | buy |
| SUPERSTRING CAPITAL MANAGEMENT LP | 237,487 | 276,474 | +38,987 | 5.08 | 5.10 | +0.02 | buy |
| TUDOR INVESTMENT CORP ET AL | 163,378 | 201,508 | +38,130 | 0.03 | 0.02 | -0.00 | buy |
| Exome Asset Management LLC | 118,017 | 153,278 | +35,261 | 1.89 | 1.87 | -0.02 | buy |
| Knott David M Jr | 228,000 | 260,000 | +32,000 | 1.93 | 1.74 | -0.18 | buy |
| SG Americas Securities, LLC | 0 | 31,926 | +31,926 | 0.00 | 0.00 | +0.00 | buy |
| AlphaQuest LLC | 3,591 | 35,250 | +31,659 | 0.01 | 0.05 | +0.04 | buy |
| S&CO INC | 0 | 28,000 | +28,000 | 0.00 | 0.03 | +0.03 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 147,114 | 175,033 | +27,919 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,976,661 | 2,003,701 | +27,040 | 0.00 | 0.00 | -0.00 | buy |
| FRANKLIN RESOURCES INC | 52,836 | 76,511 | +23,675 | 0.00 | 0.00 | +0.00 | buy |
| Hennion & Walsh Asset Management, Inc. | 0 | 21,659 | +21,659 | 0.00 | 0.01 | +0.01 | buy |
| Tower Research Capital LLC (TRC) | 3,524 | 24,998 | +21,474 | 0.00 | 0.01 | +0.01 | buy |
| Engineers Gate Manager LP | 89,784 | 110,807 | +21,023 | 0.03 | 0.02 | -0.01 | buy |
| Mach-1 Financial Group, LLC | 0 | 20,313 | +20,313 | 0.00 | 0.09 | +0.09 | buy |
| Point72 (DIFC) Ltd | 0 | 19,767 | +19,767 | 0.00 | 0.02 | +0.02 | buy |
| EMERALD MUTUAL FUND ADVISERS TRUST | 1,121,886 | 1,141,428 | +19,542 | 1.43 | 1.03 | -0.40 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 53,309 | 71,372 | +18,063 | 0.00 | 0.00 | +0.00 | buy |
| AIGEN INVESTMENT MANAGEMENT, LP | 0 | 16,789 | +16,789 | 0.00 | 0.03 | +0.03 | buy |
| Campbell & CO Investment Adviser LLC | 0 | 16,316 | +16,316 | 0.00 | 0.02 | +0.02 | buy |
| Militia Capital Partners, LP | 0 | 15,400 | +15,400 | 0.00 | 0.11 | +0.11 | buy |
| EMERALD ADVISERS, LLC | 2,077,173 | 2,091,360 | +14,187 | 1.68 | 1.13 | -0.54 | buy |
| VICTORY CAPITAL MANAGEMENT INC | 10,541 | 24,649 | +14,108 | 0.00 | 0.00 | +0.00 | buy |
| ADVENT CAPITAL MANAGEMENT /DE/ | 0 | 14,000 | +14,000 | 0.00 | 0.00 | +0.00 | buy |
| Quantinno Capital Management LP | 0 | 13,371 | +13,371 | 0.00 | 0.00 | +0.00 | buy |
| PRELUDE CAPITAL MANAGEMENT, LLC | 35,909 | 49,057 | +13,148 | 0.06 | 0.07 | +0.01 | buy |
| Russell Investments Group, Ltd. | 224,936 | 237,720 | +12,784 | 0.01 | 0.00 | -0.00 | buy |
| TWO SIGMA ADVISERS, LP | 1,045,700 | 1,057,700 | +12,000 | 0.04 | 0.03 | -0.01 | buy |
| FARALLON CAPITAL MANAGEMENT LLC | 0 | 12,000 | +12,000 | 0.00 | 0.00 | +0.00 | buy |
| Corton Capital Inc. | 0 | 10,732 | +10,732 | 0.00 | 0.18 | +0.18 | buy |
| Gallagher Fiduciary Advisors, LLC | 0 | 10,463 | +10,463 | 0.00 | 0.01 | +0.01 | buy |
| Atria Investments, Inc | 0 | 10,417 | +10,417 | 0.00 | 0.00 | +0.00 | buy |
| Virtus Investment Advisers, LLC | 20,046 | 29,745 | +9,699 | 0.10 | 0.15 | +0.05 | buy |
| RHUMBLINE ADVISERS | 124,550 | 131,959 | +7,409 | 0.00 | 0.00 | -0.00 | buy |
| Diversified Trust Co | 15,959 | 22,899 | +6,940 | 0.01 | 0.01 | +0.00 | buy |
| Creative Planning | 25,103 | 31,627 | +6,524 | 0.00 | 0.00 | -0.00 | buy |
| Cresset Asset Management, LLC | 22,828 | 28,875 | +6,047 | 0.00 | 0.00 | +0.00 | buy |
| Brooklyn Investment Group | 0 | 5,365 | +5,365 | 0.00 | 0.01 | +0.01 | buy |
| RICE HALL JAMES & ASSOCIATES, LLC | 88,617 | 93,612 | +4,995 | 0.09 | 0.07 | -0.02 | buy |
| Headlands Technologies LLC | 0 | 4,936 | +4,936 | 0.00 | 0.01 | +0.01 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 22,914 | 27,814 | +4,900 | 0.00 | 0.00 | -0.00 | buy |
| KLP KAPITALFORVALTNING AS | 15,000 | 19,500 | +4,500 | 0.00 | 0.00 | -0.00 | buy |
| ARMISTICE CAPITAL, LLC | 8,872,000 | 8,876,000 | +4,000 | 4.25 | 4.98 | +0.73 | buy |
| MetLife Investment Management, LLC | 49,288 | 52,578 | +3,290 | 0.00 | 0.00 | -0.00 | buy |
| Swiss National Bank | 158,100 | 161,100 | +3,000 | 0.00 | 0.00 | -0.00 | buy |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 22,956 | 25,728 | +2,772 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 66,067 | 68,820 | +2,753 | 0.00 | 0.00 | -0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 41,489 | 44,102 | +2,613 | 0.00 | 0.00 | -0.00 | buy |
| WELLINGTON MANAGEMENT GROUP LLP | 33,170 | 35,009 | +1,839 | 0.00 | 0.00 | -0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 18,103 | 19,764 | +1,661 | 0.00 | 0.00 | -0.00 | buy |