| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ARMISTICE CAPITAL, LLC | 7,500,000 | 7,648,000 | +148,000 | 1.61 | 2.80 | +1.19 | buy |
| VANGUARD GROUP INC | 6,619,756 | 6,902,150 | +282,394 | 0.00 | 0.00 | +0.00 | buy |
| Rock Springs Capital Management LP | 4,482,265 | 4,684,476 | +202,211 | 1.11 | 2.13 | +1.02 | buy |
| Woodline Partners LP | 1,276,878 | 4,340,340 | +3,063,462 | 0.10 | 0.51 | +0.41 | buy |
| MACQUARIE GROUP LTD | 4,367,830 | 4,272,914 | -94,916 | 0.04 | 0.06 | +0.02 | sell |
| STATE STREET CORP | 3,510,677 | 2,736,696 | -773,981 | 0.00 | 0.00 | +0.00 | sell |
| JANE STREET GROUP, LLC | 2,833,000 | 2,633,000 | -200,000 | 0.00 | 0.00 | +0.00 | sell |
| EMERALD ADVISERS, LLC | 1,637,146 | 1,960,659 | +323,513 | 0.56 | 1.06 | +0.50 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 2,203,814 | 1,875,014 | -328,800 | 0.03 | 0.04 | +0.01 | sell |
| D. E. Shaw & Co., Inc. | 1,533,072 | 1,840,069 | +306,997 | 0.02 | 0.03 | +0.02 | buy |
| Finepoint Capital LP | 1,776,728 | 1,782,267 | +5,539 | 4.15 | 3.03 | -1.11 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,666,301 | 1,731,045 | +64,744 | 0.00 | 0.00 | +0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 1,878,954 | 1,714,620 | -164,334 | 0.00 | 0.00 | +0.00 | sell |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 1,889,844 | 1,590,377 | -299,467 | 0.06 | 0.09 | +0.02 | sell |
| Assenagon Asset Management S.A. | 2,214,099 | 1,374,522 | -839,577 | 0.05 | 0.04 | -0.01 | sell |
| Kynam Capital Management, LP | 2,021,659 | 1,371,511 | -650,148 | 1.74 | 1.49 | -0.25 | sell |
| MORGAN STANLEY | 3,489,662 | 1,349,408 | -2,140,254 | 0.00 | 0.00 | -0.00 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 1,285,379 | +1,285,379 | 0.00 | 0.05 | +0.05 | buy |
| EMERALD MUTUAL FUND ADVISERS TRUST | 941,265 | 1,185,709 | +244,444 | 0.41 | 0.86 | +0.46 | buy |
| Logos Global Management LP | 0 | 1,100,000 | +1,100,000 | 0.00 | 1.72 | +1.72 | buy |
| Parkman Healthcare Partners LLC | 969,892 | 1,086,067 | +116,175 | 1.09 | 1.94 | +0.85 | buy |
| Eversept Partners, LP | 1,091,165 | 869,913 | -221,252 | 0.69 | 0.93 | +0.25 | sell |
| HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 615,000 | 843,300 | +228,300 | 0.01 | 0.03 | +0.01 | buy |
| CITADEL ADVISORS LLC | 640,309 | 775,089 | +134,780 | 0.01 | 0.01 | +0.01 | buy |
| Pictet Asset Management Holding SA | 977,954 | 762,908 | -215,046 | 0.01 | 0.01 | +0.00 | sell |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC | 0 | 753,795 | +753,795 | 0.00 | 0.04 | +0.04 | buy |
| JPMORGAN CHASE & CO | 785,295 | 748,558 | -36,737 | 0.00 | 0.00 | +0.00 | sell |
| TWO SIGMA ADVISERS, LP | 553,300 | 720,400 | +167,100 | 0.01 | 0.02 | +0.01 | buy |
| GOLDMAN SACHS GROUP INC | 778,649 | 702,606 | -76,043 | 0.00 | 0.00 | +0.00 | sell |
| NORTHERN TRUST CORP | 704,562 | 678,037 | -26,525 | 0.00 | 0.00 | +0.00 | sell |
| SCHRODER INVESTMENT MANAGEMENT GROUP | 634,401 | 677,452 | +43,051 | 0.01 | 0.01 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 946,601 | 675,085 | -271,516 | 0.00 | 0.00 | +0.00 | sell |
| FEDERATED HERMES, INC. | 41,717 | 623,815 | +582,098 | 0.00 | 0.02 | +0.02 | buy |
| PRUDENTIAL FINANCIAL INC | 435,641 | 603,941 | +168,300 | 0.01 | 0.01 | +0.01 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 568,593 | 567,409 | -1,184 | 0.00 | 0.00 | +0.00 | sell |
| Deep Track Capital, LP | 7,370,000 | 531,857 | -6,838,143 | 1.81 | 0.24 | -1.57 | sell |
| Connor, Clark & Lunn Investment Management Ltd. | 472,396 | 525,381 | +52,985 | 0.02 | 0.04 | +0.02 | buy |
| GW&K Investment Management, LLC | 510,126 | 497,925 | -12,201 | 0.04 | 0.06 | +0.02 | sell |
| Walleye Capital LLC | 266,471 | 488,453 | +221,982 | 0.02 | 0.07 | +0.05 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 400,000 | 400,000 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Invesco Ltd. | 30,980 | 365,206 | +334,226 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 314,180 | 360,083 | +45,903 | 0.01 | 0.01 | +0.01 | buy |
| Trexquant Investment LP | 174,488 | 356,708 | +182,220 | 0.02 | 0.06 | +0.04 | buy |
| READYSTATE ASSET MANAGEMENT LP | 0 | 332,939 | +332,939 | 0.00 | 0.24 | +0.24 | buy |
| UBS Group AG | 131,506 | 326,235 | +194,729 | 0.00 | 0.00 | +0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 90,881 | 320,333 | +229,452 | 0.00 | 0.02 | +0.02 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 0 | 313,242 | +313,242 | 0.00 | 0.04 | +0.04 | buy |
| JANE STREET GROUP, LLC | 409,857 | 311,260 | -98,597 | 0.00 | 0.01 | +0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 33,441 | 281,349 | +247,908 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 37,480 | 276,530 | +239,050 | 0.01 | 0.08 | +0.07 | buy |
| PDT Partners, LLC | 238,783 | 264,273 | +25,490 | 0.19 | 0.33 | +0.14 | buy |
| Knott David M Jr | 265,966 | 258,231 | -7,735 | 0.87 | 1.27 | +0.40 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 24,942 | 222,470 | +197,528 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 264,816 | 209,350 | -55,466 | 0.00 | 0.00 | +0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 74,069 | 194,663 | +120,594 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 185,123 | 175,820 | -9,303 | 0.01 | 0.02 | +0.01 | sell |
| BARCLAYS PLC | 186,312 | 168,768 | -17,544 | 0.00 | 0.00 | +0.00 | sell |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 178,749 | 163,175 | -15,574 | 0.00 | 0.00 | +0.00 | sell |
| Russell Investments Group, Ltd. | 166,057 | 161,266 | -4,791 | 0.00 | 0.00 | +0.00 | sell |
| Birchview Capital, LP | 122,000 | 148,000 | +26,000 | 0.93 | 1.79 | +0.87 | buy |
| FMR LLC | 115,644 | 147,416 | +31,772 | 0.00 | 0.00 | +0.00 | buy |
| HighVista Strategies LLC | 219,416 | 147,233 | -72,183 | 0.66 | 0.71 | +0.05 | sell |
| NOMURA HOLDINGS INC | 575,870 | 146,736 | -429,134 | 0.03 | 0.02 | -0.01 | sell |
| Swiss National Bank | 134,700 | 134,700 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Hudson Bay Capital Management LP | 44,561 | 125,000 | +80,439 | 0.00 | 0.01 | +0.01 | buy |
| AMERIPRISE FINANCIAL INC | 602,108 | 122,701 | -479,407 | 0.00 | 0.00 | -0.00 | sell |
| Crestline Management, LP | 103,353 | 120,725 | +17,372 | 0.07 | 0.10 | +0.03 | buy |
| RHUMBLINE ADVISERS | 125,660 | 118,608 | -7,052 | 0.00 | 0.00 | +0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 2,949,335 | 114,613 | -2,834,722 | 0.02 | 0.00 | -0.02 | sell |
| MARSHALL WACE, LLP | 0 | 111,341 | +111,341 | 0.00 | 0.00 | +0.00 | buy |
| Palo Alto Investors LP | 110,719 | 110,719 | 0 | 0.11 | 0.20 | +0.10 | hold |
| HRT FINANCIAL LP | 91,464 | 107,492 | +16,028 | 0.00 | 0.01 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 346,068 | 103,933 | -242,135 | 0.05 | 0.02 | -0.03 | sell |
| RICE HALL JAMES & ASSOCIATES, LLC | 76,174 | 94,736 | +18,562 | 0.04 | 0.07 | +0.03 | buy |
| Rafferty Asset Management, LLC | 182,292 | 91,771 | -90,521 | 0.01 | 0.00 | -0.00 | sell |
| Legal & General Group Plc | 74,240 | 80,958 | +6,718 | 0.00 | 0.00 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 0 | 71,800 | +71,800 | 0.00 | 0.00 | +0.00 | buy |
| NORGES BANK | 71,000 | 71,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 70,630 | 70,630 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 67,366 | 65,151 | -2,215 | 0.00 | 0.00 | +0.00 | sell |
| Engineers Gate Manager LP | 41,760 | 62,245 | +20,485 | 0.01 | 0.02 | +0.01 | buy |
| Brevan Howard Capital Management LP | 61,295 | 61,695 | +400 | 0.03 | 0.04 | +0.01 | buy |
| Verition Fund Management LLC | 28,288 | 60,871 | +32,583 | 0.00 | 0.01 | +0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 279,104 | 58,111 | -220,993 | 0.01 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 44,953 | 57,601 | +12,648 | 0.00 | 0.00 | +0.00 | buy |
| OAK RIDGE INVESTMENTS LLC | 57,584 | 55,339 | -2,245 | 0.05 | 0.07 | +0.02 | sell |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 50,880 | 50,880 | 0 | 0.00 | 0.00 | +0.00 | hold |
| OPPENHEIMER & CO INC | 0 | 48,139 | +48,139 | 0.00 | 0.01 | +0.01 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 29,114 | 47,045 | +17,931 | 0.00 | 0.00 | +0.00 | buy |
| VIRTUS ADVISERS, LLC | 45,490 | 45,490 | 0 | 0.18 | 0.30 | +0.11 | hold |
| Fisher Asset Management, LLC | 43,182 | 43,182 | 0 | 0.00 | 0.00 | +0.00 | hold |
| HSBC HOLDINGS PLC | 48,994 | 41,816 | -7,178 | 0.00 | 0.00 | +0.00 | sell |
| MetLife Investment Management, LLC | 40,832 | 41,143 | +311 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 44,284 | 40,465 | -3,819 | 0.00 | 0.00 | +0.00 | sell |
| SIMPLEX TRADING, LLC | 80,989 | 40,461 | -40,528 | 0.02 | 0.02 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 42,540 | 39,732 | -2,808 | 0.00 | 0.00 | +0.00 | sell |
| Corebridge Financial, Inc. | 39,639 | 39,397 | -242 | 0.00 | 0.00 | +0.00 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 104,748 | 38,297 | -66,451 | 0.00 | 0.00 | -0.00 | sell |
| TUDOR INVESTMENT CORP ET AL | 37,283 | 38,144 | +861 | 0.00 | 0.01 | +0.00 | buy |
| Semanteon Capital Management, LP | 0 | 36,699 | +36,699 | 0.00 | 0.35 | +0.35 | buy |