| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ADAR1 Capital Management, LLC | 140,672 | 1,288,053 | +1,147,381 | 0.29 | 2.25 | +1.96 | buy |
| UBS Group AG | 132,540 | 985,831 | +853,291 | 0.00 | 0.01 | +0.01 | buy |
| Lynx1 Capital Management LP | 2,611,568 | 3,408,937 | +797,369 | 13.96 | 14.62 | +0.65 | buy |
| BlackRock, Inc. | 5,754,957 | 6,455,997 | +701,040 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 36,410 | 684,340 | +647,930 | 0.00 | 0.01 | +0.01 | buy |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 250,461 | 810,530 | +560,069 | 0.00 | 0.01 | +0.01 | buy |
| Sixth Street Partners Management Company, L.P. | 0 | 538,128 | +538,128 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asset Management, L.P. | 0 | 506,344 | +506,344 | 0.00 | 0.03 | +0.03 | buy |
| D. E. Shaw & Co., Inc. | 2,681,169 | 3,107,005 | +425,836 | 0.07 | 0.07 | -0.00 | buy |
| Qube Research & Technologies Ltd | 187,667 | 597,638 | +409,971 | 0.01 | 0.02 | +0.02 | buy |
| GOLDMAN SACHS GROUP INC | 805,776 | 1,150,932 | +345,156 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 200,061 | 520,083 | +320,022 | 0.06 | 0.10 | +0.05 | buy |
| Ensign Peak Advisors, Inc | 6,570 | 297,630 | +291,060 | 0.00 | 0.02 | +0.02 | buy |
| TWO SIGMA INVESTMENTS, LP | 251,636 | 536,380 | +284,744 | 0.01 | 0.01 | +0.01 | buy |
| Parkman Healthcare Partners LLC | 403,525 | 669,046 | +265,521 | 1.42 | 2.55 | +1.13 | buy |
| Foresite Capital Management VI LLC | 525,000 | 785,000 | +260,000 | 3.86 | 4.53 | +0.67 | buy |
| FARALLON CAPITAL MANAGEMENT LLC | 5,684,000 | 5,917,400 | +233,400 | 1.14 | 1.29 | +0.15 | buy |
| JPMORGAN CHASE & CO | 151,558 | 359,756 | +208,198 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 0 | 182,773 | +182,773 | 0.00 | 0.06 | +0.06 | buy |
| STATE STREET CORP | 3,364,879 | 3,533,633 | +168,754 | 0.00 | 0.00 | -0.00 | buy |
| FIRST TRUST ADVISORS LP | 0 | 165,587 | +165,587 | 0.00 | 0.00 | +0.00 | buy |
| Nuveen, LLC | 722,348 | 873,560 | +151,212 | 0.01 | 0.01 | +0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 149,886 | +149,886 | 0.00 | 0.10 | +0.10 | buy |
| PANAGORA ASSET MANAGEMENT INC | 238,468 | 373,931 | +135,463 | 0.03 | 0.04 | +0.01 | buy |
| CITADEL ADVISORS LLC | 619,613 | 732,687 | +113,074 | 0.01 | 0.02 | +0.00 | buy |
| Squarepoint Ops LLC | 208,888 | 321,138 | +112,250 | 0.02 | 0.02 | +0.01 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 1,467,910 | 1,574,268 | +106,358 | 0.00 | 0.00 | +0.00 | buy |
| KENNEDY CAPITAL MANAGEMENT LLC | 275,456 | 373,230 | +97,774 | 0.20 | 0.25 | +0.05 | buy |
| DIMENSIONAL FUND ADVISORS LP | 1,151,614 | 1,248,738 | +97,124 | 0.01 | 0.01 | +0.00 | buy |
| Jain Global LLC | 0 | 91,647 | +91,647 | 0.00 | 0.04 | +0.04 | buy |
| Campbell & CO Investment Adviser LLC | 0 | 73,095 | +73,095 | 0.00 | 0.14 | +0.14 | buy |
| CITIGROUP INC | 17,096 | 89,167 | +72,071 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 477,032 | 538,128 | +61,096 | 0.00 | 0.00 | +0.00 | buy |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 0 | 49,764 | +49,764 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 509,272 | 554,709 | +45,437 | 0.00 | 0.00 | +0.00 | buy |
| TFG Asset Management GP Ltd | 164,839 | 205,579 | +40,740 | 1.10 | 1.24 | +0.15 | buy |
| IEQ CAPITAL, LLC | 0 | 40,404 | +40,404 | 0.00 | 0.01 | +0.01 | buy |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 60,679 | 99,726 | +39,047 | 0.00 | 0.01 | +0.00 | buy |
| Assenagon Asset Management S.A. | 67,153 | 103,955 | +36,802 | 0.00 | 0.01 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,344,953 | 1,375,558 | +30,605 | 0.06 | 0.05 | -0.01 | buy |
| WELLS FARGO & COMPANY/MN | 22,763 | 53,240 | +30,477 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 9,121 | 39,072 | +29,951 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 0 | 29,139 | +29,139 | 0.00 | 0.00 | +0.00 | buy |
| Quadrature Capital Ltd | 0 | 28,111 | +28,111 | 0.00 | 0.01 | +0.01 | buy |
| AXQ CAPITAL, LP | 0 | 27,656 | +27,656 | 0.00 | 0.11 | +0.11 | buy |
| Aquatic Capital Management LLC | 11,322 | 38,627 | +27,305 | 0.01 | 0.05 | +0.04 | buy |
| Caption Management, LLC | 12,349 | 39,249 | +26,900 | 0.02 | 0.05 | +0.03 | buy |
| Russell Investments Group, Ltd. | 39,710 | 66,235 | +26,525 | 0.00 | 0.00 | +0.00 | buy |
| Engineers Gate Manager LP | 28,920 | 53,912 | +24,992 | 0.01 | 0.03 | +0.01 | buy |
| Bridgefront Capital, LLC | 6,551 | 31,097 | +24,546 | 0.06 | 0.30 | +0.25 | buy |
| MERCER GLOBAL ADVISORS INC /ADV | 0 | 21,295 | +21,295 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 0 | 20,229 | +20,229 | 0.00 | 0.00 | +0.00 | buy |
| Quarry LP | 0 | 20,147 | +20,147 | 0.00 | 0.12 | +0.12 | buy |
| Trexquant Investment LP | 75,298 | 93,539 | +18,241 | 0.02 | 0.02 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 0 | 17,959 | +17,959 | 0.00 | 0.00 | +0.00 | buy |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 950 | 18,028 | +17,078 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 151,430 | 168,153 | +16,723 | 0.00 | 0.00 | -0.00 | buy |
| Quantinno Capital Management LP | 27,591 | 43,514 | +15,923 | 0.00 | 0.00 | +0.00 | buy |
| FOX RUN MANAGEMENT, L.L.C. | 0 | 15,622 | +15,622 | 0.00 | 0.10 | +0.10 | buy |
| AMERICAN CENTURY COMPANIES INC | 120,253 | 134,512 | +14,259 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 47,701 | 60,059 | +12,358 | 0.01 | 0.01 | +0.00 | buy |
| Bank of New York Mellon Corp | 186,791 | 198,685 | +11,894 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 50,384 | 62,228 | +11,844 | 0.00 | 0.00 | +0.00 | buy |
| CAPTRUST FINANCIAL ADVISORS | 0 | 11,351 | +11,351 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 423,915 | 434,719 | +10,804 | 0.00 | 0.00 | +0.00 | buy |
| ALLSTATE CORP | 0 | 9,485 | +9,485 | 0.00 | 0.00 | +0.00 | buy |
| CAPSTONE INVESTMENT ADVISORS, LLC | 0 | 9,196 | +9,196 | 0.00 | 0.00 | +0.00 | buy |
| Diversified Trust Co | 15,319 | 23,948 | +8,629 | 0.01 | 0.01 | +0.00 | buy |
| Virtus Investment Advisers, LLC | 30,959 | 39,473 | +8,514 | 0.29 | 0.34 | +0.05 | buy |
| Creative Planning | 13,333 | 21,604 | +8,271 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 0 | 7,717 | +7,717 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 58,151 | 65,779 | +7,628 | 0.01 | 0.01 | -0.00 | buy |
| Financiere des Professionnels - Fonds d,investissement inc. | 0 | 7,505 | +7,505 | 0.00 | 0.02 | +0.02 | buy |
| MARTINGALE ASSET MANAGEMENT L P | 35,814 | 43,009 | +7,195 | 0.03 | 0.04 | +0.01 | buy |
| Handelsbanken Fonder AB | 19,323 | 26,123 | +6,800 | 0.00 | 0.00 | +0.00 | buy |
| CANADA LIFE ASSURANCE Co | 10,684 | 17,121 | +6,437 | 0.00 | 0.00 | +0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 110,679 | 116,909 | +6,230 | 0.00 | 0.00 | +0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 0 | 6,172 | +6,172 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 73,369 | 79,441 | +6,072 | 0.00 | 0.00 | +0.00 | buy |
| XPONANCE, INC. | 0 | 5,757 | +5,757 | 0.00 | 0.00 | +0.00 | buy |
| Merit Financial Group, LLC | 0 | 5,556 | +5,556 | 0.00 | 0.00 | +0.00 | buy |
| Arax Advisory Partners | 120 | 5,376 | +5,256 | 0.00 | 0.00 | +0.00 | buy |
| CenterBook Partners LP | 17,445 | 21,885 | +4,440 | 0.03 | 0.04 | +0.01 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 27,810 | 32,235 | +4,425 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 4,044 | 7,628 | +3,584 | 0.00 | 0.00 | +0.00 | buy |
| HARBOR CAPITAL ADVISORS, INC. | 43,005 | 46,550 | +3,545 | 0.12 | 0.12 | -0.00 | buy |
| Inspire Investing, LLC | 14,740 | 18,269 | +3,529 | 0.05 | 0.03 | -0.02 | buy |
| Swiss National Bank | 108,860 | 111,660 | +2,800 | 0.00 | 0.00 | +0.00 | buy |
| Knott David M Jr | 93,058 | 95,058 | +2,000 | 1.87 | 1.86 | -0.01 | buy |
| Allworth Financial LP | 68 | 1,971 | +1,903 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 15,640 | 17,444 | +1,804 | 0.00 | 0.00 | +0.00 | buy |
| Tidal Investments LLC | 14,376 | 16,100 | +1,724 | 0.00 | 0.00 | -0.00 | buy |
| MetLife Investment Management, LLC | 32,858 | 34,470 | +1,612 | 0.01 | 0.01 | +0.00 | buy |
| Versant Capital Management, Inc | 418 | 2,001 | +1,583 | 0.00 | 0.01 | +0.01 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 9,996 | 11,350 | +1,354 | 0.00 | 0.00 | +0.00 | buy |
| Integrated Wealth Concepts LLC | 0 | 1,269 | +1,269 | 0.00 | 0.00 | +0.00 | buy |
| Quantbot Technologies LP | 0 | 1,172 | +1,172 | 0.00 | 0.00 | +0.00 | buy |
| Pacer Advisors, Inc. | 0 | 928 | +928 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 9,045 | 9,955 | +910 | 0.00 | 0.00 | +0.00 | buy |
| PNC FINANCIAL SERVICES GROUP, INC. | 4,940 | 5,836 | +896 | 0.00 | 0.00 | +0.00 | buy |