| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Telemark Asset Management, LLC | 76,000 | 1,326,000 | +1,250,000 | 0.02 | 0.20 | +0.18 | buy |
| Cannell & Spears LLC | 0 | 205,605 | +205,605 | 0.00 | 0.01 | +0.01 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 190,376 | +190,376 | 0.00 | 0.00 | +0.00 | buy |
| Cetera Investment Advisers | 0 | 78,000 | +78,000 | 0.00 | 0.00 | +0.00 | buy |
| Allworth Financial LP | 55,853 | 99,331 | +43,478 | 0.00 | 0.00 | +0.00 | buy |
| Opaleye Management Inc. | 496,500 | 534,657 | +38,157 | 0.96 | 0.17 | -0.79 | buy |
| CITIGROUP INC | 42,627 | 71,286 | +28,659 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 357,118 | 385,145 | +28,027 | 0.00 | 0.00 | -0.00 | buy |
| GOLDMAN SACHS GROUP INC | 0 | 27,538 | +27,538 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 13,644 | +13,644 | 0.00 | 0.00 | +0.00 | buy |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 912,945 | 925,614 | +12,669 | 0.33 | 0.26 | -0.07 | buy |
| Jefferies Financial Group Inc. | 0 | 11,400 | +11,400 | 0.00 | 0.00 | +0.00 | buy |
| OMERS ADMINISTRATION Corp | 0 | 11,221 | +11,221 | 0.00 | 0.00 | +0.00 | buy |
| Brevan Howard Capital Management LP | 0 | 10,525 | +10,525 | 0.00 | 0.00 | +0.00 | buy |
| NWAM LLC | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 883,653 | 893,203 | +9,550 | 0.00 | 0.00 | -0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 91,320 | 100,755 | +9,435 | 0.00 | 0.00 | -0.00 | buy |
| Qube Research & Technologies Ltd | 65,609 | 69,497 | +3,888 | 0.00 | 0.00 | -0.00 | buy |
| NORTHERN TRUST CORP | 31,113 | 32,805 | +1,692 | 0.00 | 0.00 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 1,071 | +1,071 | 0.00 | 0.00 | +0.00 | buy |
| MACQUARIE GROUP LTD | 0 | 512 | +512 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 229,200 | 229,663 | +463 | 0.01 | 0.01 | -0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 15,913 | 16,313 | +400 | 0.00 | 0.00 | -0.00 | buy |
| CIBC Private Wealth Group LLC | 13,100 | 13,100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HighTower Advisors, LLC | 131,434 | 131,434 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Birchview Capital, LP | 5,348,273 | 5,348,273 | 0 | 7.66 | 6.22 | -1.44 | hold |
| Corient Private Wealth LLC | 15,497 | 15,497 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BARCLAYS PLC | 9,291 | 9,291 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 20,622 | 20,622 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STATE STREET CORP | 275,350 | 275,350 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Tower Research Capital LLC (TRC) | 8,834 | 7,728 | -1,106 | 0.00 | 0.00 | +0.00 | sell |
| VANGUARD GROUP INC | 811,751 | 807,928 | -3,823 | 0.00 | 0.00 | -0.00 | sell |
| BLAIR WILLIAM & CO/IL | 89,800 | 79,800 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 23,678 | 0 | -23,678 | 0.00 | 0.00 | -0.00 | sell |
| ExodusPoint Capital Management, LP | 23,963 | 0 | -23,963 | 0.00 | 0.00 | -0.00 | sell |
| ORACLE INVESTMENT MANAGEMENT INC | 60,939 | 30,351 | -30,588 | 0.12 | 0.03 | -0.09 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 48,800 | 13,200 | -35,600 | 0.00 | 0.00 | -0.00 | sell |
| Worth Venture Partners, LLC | 1,141,794 | 0 | -1,141,794 | 1.14 | 0.00 | -1.14 | sell |
| AIGH Capital Management LLC | 4,658,946 | 3,321,085 | -1,337,861 | 3.39 | 2.29 | -1.10 | sell |