| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Wilmington Savings Fund Society, FSB | 0 | 6,095,034 | +6,095,034 | 0.00 | 0.19 | +0.19 | buy |
| FARALLON CAPITAL MANAGEMENT LLC | 1,878,175 | 4,636,791 | +2,758,616 | 0.02 | 0.05 | +0.03 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 1,808,959 | 3,561,094 | +1,752,135 | 0.68 | 1.43 | +0.75 | buy |
| PERKINS CAPITAL MANAGEMENT INC | 414,782 | 724,782 | +310,000 | 0.60 | 1.21 | +0.61 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 533,852 | 804,576 | +270,724 | 0.00 | 0.00 | +0.00 | buy |
| Monashee Investment Management LLC | 3,260,879 | 3,500,879 | +240,000 | 0.65 | 0.67 | +0.03 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 165,342 | +165,342 | 0.00 | 0.00 | +0.00 | buy |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 0 | 146,941 | +146,941 | 0.00 | 0.03 | +0.03 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 128,273 | +128,273 | 0.00 | 0.00 | +0.00 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 185,063 | 284,511 | +99,448 | 0.01 | 0.01 | +0.00 | buy |
| GTS SECURITIES LLC | 0 | 80,330 | +80,330 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 3,068 | 72,433 | +69,365 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 2,906,504 | 2,962,690 | +56,186 | 0.00 | 0.00 | +0.00 | buy |
| Jefferies Financial Group Inc. | 0 | 55,400 | +55,400 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 40,689 | +40,689 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 11,100 | 41,157 | +30,057 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 1,857 | 23,036 | +21,179 | 0.00 | 0.00 | +0.00 | buy |
| Cubist Systematic Strategies, LLC | 0 | 10,500 | +10,500 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 10,278 | +10,278 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 2,952 | +2,952 | 0.00 | 0.00 | +0.00 | buy |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 968,617 | 971,197 | +2,580 | 0.28 | 0.30 | +0.02 | buy |
| ORACLE INVESTMENT MANAGEMENT INC | 28,916 | 28,916 | 0 | 0.05 | 0.04 | -0.01 | hold |
| PRUDENTIAL FINANCIAL INC | 29,800 | 29,800 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PERCEPTIVE ADVISORS LLC | 2,173,880 | 2,173,880 | 0 | 0.08 | 0.08 | +0.00 | hold |
| CIBC Private Wealth Group LLC | 29,337 | 29,337 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Bank of New York Mellon Corp | 14,002 | 14,002 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Telemark Asset Management, LLC | 8,282,490 | 8,282,490 | 0 | 1.14 | 1.49 | +0.34 | hold |
| Cannell & Spears LLC | 205,605 | 205,605 | 0 | 0.01 | 0.01 | +0.00 | hold |
| HighTower Advisors, LLC | 131,434 | 131,434 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Allworth Financial LP | 99,331 | 99,331 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMH Equity Ltd | 696,073 | 696,073 | 0 | 1.58 | 1.63 | +0.05 | hold |
| Birchview Capital, LP | 5,696,113 | 5,696,113 | 0 | 8.04 | 8.76 | +0.72 | hold |
| Cetera Investment Advisers | 78,000 | 78,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Ferguson Shapiro LLC | 10,000 | 10,000 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Corient Private Wealth LLC | 58,975 | 58,975 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NORTHERN TRUST CORP | 43,764 | 43,764 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 20,622 | 20,622 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BLAIR WILLIAM & CO/IL | 83,400 | 83,400 | 0 | 0.00 | 0.00 | +0.00 | hold |
| STATE STREET CORP | 288,550 | 288,550 | 0 | 0.00 | 0.00 | +0.00 | hold |
| SIMPLEX TRADING, LLC | 860 | 0 | -860 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 931,181 | 924,233 | -6,948 | 0.00 | 0.00 | +0.00 | sell |
| Sio Capital Management, LLC | 4,347,855 | 4,338,514 | -9,341 | 2.51 | 3.46 | +0.95 | sell |
| TWO SIGMA SECURITIES, LLC | 11,063 | 0 | -11,063 | 0.00 | 0.00 | -0.00 | sell |
| ExodusPoint Capital Management, LP | 41,446 | 0 | -41,446 | 0.00 | 0.00 | -0.00 | sell |
| AIGH Capital Management LLC | 5,779,812 | 5,679,812 | -100,000 | 4.32 | 4.73 | +0.42 | sell |
| Opaleye Management Inc. | 4,020,000 | 3,815,000 | -205,000 | 1.41 | 1.16 | -0.24 | sell |
| LMR Partners LLP | 1,600,000 | 0 | -1,600,000 | 0.05 | 0.00 | -0.05 | sell |
| Soleus Capital Management, L.P. | 6,111,964 | 4,038,065 | -2,073,899 | 0.82 | 0.60 | -0.23 | sell |