| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 3,580,000 | 11,394,000 | +7,814,000 | 0.23 | 0.63 | +0.40 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 302,612 | 515,006 | +212,394 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 238,725 | 297,156 | +58,431 | 0.00 | 0.00 | +0.00 | buy |
| Evernest Financial Advisors, LLC | 0 | 40,000 | +40,000 | 0.00 | 0.01 | +0.01 | buy |
| TWO SIGMA SECURITIES, LLC | 0 | 24,102 | +24,102 | 0.00 | 0.00 | +0.00 | buy |
| Private Advisor Group, LLC | 85,000 | 100,000 | +15,000 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 2,150,912 | 2,150,912 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ORBIMED ADVISORS LLC | 73,114,592 | 73,114,592 | 0 | 0.92 | 0.90 | -0.01 | hold |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 293,500 | 293,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| PRUDENTIAL FINANCIAL INC | 29,000 | 29,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| AMH Equity Ltd | 190,500 | 190,500 | 0 | 0.18 | 0.17 | -0.01 | hold |
| Crescent Grove Advisors, LLC | 212,024 | 212,024 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Midwest Professional Planners, LTD. | 35,744 | 35,744 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Altium Capital Management LLC | 7,415,413 | 7,415,413 | 0 | 1.93 | 1.49 | -0.44 | hold |
| Juniper Investment Company, LLC | 1,318,944 | 1,318,944 | 0 | 0.40 | 0.37 | -0.03 | hold |
| Cornerstone Planning Group LLC | 12 | 12 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NORTHERN TRUST CORP | 58,666 | 58,666 | 0 | 0.00 | 0.00 | +0.00 | hold |
| STATE STREET CORP | 31,266 | 31,266 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Qube Research & Technologies Ltd | 5 | 0 | -5 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 14,787 | 5,317 | -9,470 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 703,810 | 694,208 | -9,602 | 0.00 | 0.00 | -0.00 | sell |
| XTX Topco Ltd | 24,610 | 10,057 | -14,553 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 62,682 | 45,363 | -17,319 | 0.00 | 0.00 | -0.00 | sell |