| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BlackRock, Inc. | 423,466 | 659,402 | +235,936 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 243,089 | 429,480 | +186,391 | 0.00 | 0.00 | +0.00 | buy |
| MPM BioImpact LLC | 629,423 | 721,139 | +91,716 | 1.52 | 1.83 | +0.31 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 135,700 | 221,257 | +85,557 | 0.00 | 0.00 | +0.00 | buy |
| 683 Capital Management, LLC | 75,431 | 125,000 | +49,569 | 0.12 | 0.22 | +0.10 | buy |
| NORTHERN TRUST CORP | 63,115 | 95,030 | +31,915 | 0.00 | 0.00 | +0.00 | buy |
| ALPS ADVISORS INC | 0 | 20,550 | +20,550 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 0 | 17,580 | +17,580 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 11,336 | 27,525 | +16,189 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 157,495 | 172,620 | +15,125 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 13,800 | +13,800 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 19,048 | 26,803 | +7,755 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 11,611 | 19,099 | +7,488 | 0.00 | 0.00 | +0.00 | buy |
| MetLife Investment Management, LLC | 0 | 6,667 | +6,667 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 0 | 5,462 | +5,462 | 0.00 | 0.00 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 0 | 5,389 | +5,389 | 0.00 | 0.01 | +0.01 | buy |
| WELLS FARGO & COMPANY/MN | 0 | 4,847 | +4,847 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 15,102 | 19,407 | +4,305 | 0.00 | 0.00 | +0.00 | buy |
| VIRTUS ADVISERS, LLC | 0 | 3,533 | +3,533 | 0.00 | 0.03 | +0.03 | buy |
| CITIGROUP INC | 5,217 | 8,251 | +3,034 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 3,997 | 5,786 | +1,789 | 0.00 | 0.00 | +0.00 | buy |
| Corebridge Financial, Inc. | 3,864 | 5,122 | +1,258 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 9,274 | 10,201 | +927 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 3,715 | 4,562 | +847 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 801 | 1,150 | +349 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 10,393 | 10,652 | +259 | 0.00 | 0.00 | -0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 524 | 766 | +242 | 0.00 | 0.00 | +0.00 | buy |
| Daiwa Securities Group Inc. | 0 | 84 | +84 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 16 | 80 | +64 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 567 | 623 | +56 | 0.00 | 0.00 | -0.00 | buy |
| Spire Wealth Management | 0 | 50 | +50 | 0.00 | 0.00 | +0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 0 | 40 | +40 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 11 | 48 | +37 | 0.00 | 0.00 | +0.00 | buy |
| Truvestments Capital LLC | 0 | 10 | +10 | 0.00 | 0.00 | +0.00 | buy |
| Sterling Capital Management LLC | 7 | 14 | +7 | 0.00 | 0.00 | +0.00 | buy |
| IFP Advisors, Inc | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 708 | 708 | 0 | 0.00 | 0.00 | +0.00 | hold |
| TWIN FOCUS CAPITAL PARTNERS, LLC | 12,000 | 12,000 | 0 | 0.03 | 0.03 | +0.00 | hold |
| HALL LAURIE J TRUSTEE | 1,759 | 1,759 | 0 | 0.01 | 0.01 | +0.00 | hold |
| Freestone Capital Holdings, LLC | 25,921 | 25,921 | 0 | 0.01 | 0.02 | +0.00 | hold |
| Johnson Financial Group, Inc. | 4,618 | 4,618 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Parallel Advisors, LLC | 3 | 3 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Activest Wealth Management | 66 | 66 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CoreCap Advisors, LLC | 1 | 1 | 0 | 0.00 | 0.00 | 0.00 | hold |
| Farther Finance Advisors, LLC | 18 | 18 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Siren, L.L.C. | 572,236 | 572,236 | 0 | 0.46 | 0.45 | -0.01 | hold |
| Erste Asset Management GmbH | 173,566 | 173,566 | 0 | 0.03 | 0.04 | +0.01 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| DELPHI FINANCIAL GROUP, INC. | 22,028 | 22,028 | 0 | 0.20 | 0.21 | +0.01 | hold |
| AMALGAMATED BANK | 130 | 130 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DEUTSCHE BANK AG\ | 3,638 | 3,638 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 1,651 | 1,645 | -6 | 0.00 | 0.00 | -0.00 | sell |
| Arax Advisory Partners | 12 | 0 | -12 | 0.00 | 0.00 | -0.00 | sell |
| HAZLETT, BURT & WATSON, INC. | 12 | 0 | -12 | 0.00 | 0.00 | 0.00 | sell |
| BOOTHBAY FUND MANAGEMENT, LLC | 14,518 | 14,491 | -27 | 0.01 | 0.01 | +0.00 | sell |
| Ikarian Capital, LLC | 52,193 | 52,166 | -27 | 0.26 | 0.27 | +0.01 | sell |
| RPg Family Wealth Advisory, LLC | 100 | 0 | -100 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 12,911 | 11,812 | -1,099 | 0.00 | 0.00 | +0.00 | sell |
| NEW YORK STATE COMMON RETIREMENT FUND | 5,102 | 3,902 | -1,200 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 1,761 | 0 | -1,761 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 10,193 | 0 | -10,193 | 0.00 | 0.00 | -0.00 | sell |
| IRONWOOD INVESTMENT MANAGEMENT LLC | 14,631 | 0 | -14,631 | 0.11 | 0.00 | -0.11 | sell |
| JPMORGAN CHASE & CO | 309,018 | 274,740 | -34,278 | 0.00 | 0.00 | -0.00 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 49,497 | 0 | -49,497 | 0.00 | 0.00 | -0.00 | sell |
| Schonfeld Strategic Advisors LLC | 50,000 | 0 | -50,000 | 0.01 | 0.00 | -0.01 | sell |
| CITADEL ADVISORS LLC | 375,767 | 315,000 | -60,767 | 0.01 | 0.01 | -0.00 | sell |
| ARMISTICE CAPITAL, LLC | 98,565 | 0 | -98,565 | 0.04 | 0.00 | -0.04 | sell |
| YALE UNIVERSITY | 100,000 | 0 | -100,000 | 66.30 | 0.00 | -66.30 | sell |
| GREAT POINT PARTNERS LLC | 200,000 | 0 | -200,000 | 0.97 | 0.00 | -0.97 | sell |
| FMR LLC | 2,851,830 | 2,423,213 | -428,617 | 0.00 | 0.00 | -0.00 | sell |