| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Bain Capital Life Sciences Investors, LLC | 12,448,158 | 12,448,158 | 0 | 27.81 | 27.79 | -0.02 | hold |
| WELLINGTON MANAGEMENT GROUP LLP | 4,880,064 | 5,894,070 | +1,014,006 | 0.03 | 0.03 | +0.00 | buy |
| FMR LLC | 4,730,234 | 4,122,853 | -607,381 | 0.01 | 0.01 | -0.00 | sell |
| BAILLIE GIFFORD & CO | 3,005,998 | 3,005,998 | 0 | 0.07 | 0.07 | -0.00 | hold |
| BAMCO INC /NY/ | 1,237,506 | 2,303,877 | +1,066,371 | 0.11 | 0.18 | +0.07 | buy |
| Schusterman Interests, LLC | 1,939,201 | 1,939,201 | 0 | 14.92 | 12.94 | -1.98 | hold |
| Capricorn Investment Group LLC | 0 | 1,661,601 | +1,661,601 | 0.00 | 5.83 | +5.83 | buy |
| VANGUARD GROUP INC | 1,451,913 | 1,580,313 | +128,400 | 0.00 | 0.00 | -0.00 | buy |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0 | 1,431,011 | +1,431,011 | 0.00 | 0.01 | +0.01 | buy |
| BlackRock, Inc. | 309,569 | 1,342,139 | +1,032,570 | 0.00 | 0.00 | +0.00 | buy |
| SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC | 848,462 | 1,259,121 | +410,659 | 0.93 | 1.03 | +0.10 | buy |
| CITADEL ADVISORS LLC | 377,675 | 1,248,898 | +871,223 | 0.01 | 0.02 | +0.01 | buy |
| ALLIANCEBERNSTEIN L.P. | 1,123,063 | 1,089,030 | -34,033 | 0.01 | 0.01 | -0.00 | sell |
| JANUS HENDERSON GROUP PLC | 1,015,124 | 865,560 | -149,564 | 0.02 | 0.01 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 1,214,996 | 863,271 | -351,725 | 0.00 | 0.00 | -0.00 | sell |
| LORD, ABBETT & CO. LLC | 1,132,741 | 790,903 | -341,838 | 0.11 | 0.07 | -0.04 | sell |
| MORGAN STANLEY | 755,141 | 745,924 | -9,217 | 0.00 | 0.00 | -0.00 | sell |
| Ensign Peak Advisors, Inc | 625,812 | 700,805 | +74,993 | 0.03 | 0.04 | +0.00 | buy |
| FRANKLIN RESOURCES INC | 321,726 | 685,159 | +363,433 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 412,565 | 586,282 | +173,717 | 0.00 | 0.00 | +0.00 | buy |
| Invesco Ltd. | 102,393 | 577,397 | +475,004 | 0.00 | 0.00 | +0.00 | buy |
| EVENTIDE ASSET MANAGEMENT, LLC | 83,990 | 505,989 | +421,999 | 0.05 | 0.23 | +0.18 | buy |
| UBS Group AG | 152,412 | 501,165 | +348,753 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 255,669 | 499,925 | +244,256 | 0.00 | 0.00 | +0.00 | buy |
| RTW INVESTMENTS, LP | 495,000 | 495,000 | 0 | 0.21 | 0.14 | -0.06 | hold |
| FRED ALGER MANAGEMENT, LLC | 296,999 | 440,508 | +143,509 | 0.04 | 0.05 | +0.01 | buy |
| STATE STREET CORP | 74,480 | 322,351 | +247,871 | 0.00 | 0.00 | +0.00 | buy |
| Board of Trustees of The Leland Stanford Junior University | 312,234 | 312,234 | 0 | 1.24 | 1.83 | +0.60 | hold |
| Point72 Asset Management, L.P. | 200,482 | 304,487 | +104,005 | 0.01 | 0.01 | -0.00 | buy |
| Rock Springs Capital Management LP | 250,000 | 277,700 | +27,700 | 0.49 | 0.42 | -0.08 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 0 | 228,617 | +228,617 | 0.00 | 0.01 | +0.01 | buy |
| Alyeska Investment Group, L.P. | 85,000 | 225,000 | +140,000 | 0.01 | 0.02 | +0.01 | buy |
| EMERALD ADVISERS, LLC | 217,938 | 221,582 | +3,644 | 0.24 | 0.20 | -0.04 | buy |
| NZS Capital, LLC | 0 | 209,688 | +209,688 | 0.00 | 0.19 | +0.19 | buy |
| GILDER GAGNON HOWE & CO LLC | 119,359 | 185,868 | +66,509 | 0.04 | 0.06 | +0.02 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 101,585 | 153,346 | +51,761 | 0.00 | 0.00 | +0.00 | buy |
| Freestone Grove Partners LP | 30,000 | 150,000 | +120,000 | 0.01 | 0.03 | +0.02 | buy |
| GOLDMAN SACHS GROUP INC | 57,045 | 147,195 | +90,150 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 33,924 | 138,762 | +104,838 | 0.00 | 0.00 | +0.00 | buy |
| EMERALD MUTUAL FUND ADVISERS TRUST | 131,262 | 131,262 | 0 | 0.23 | 0.19 | -0.04 | hold |
| Catalio Capital Management, LP | 0 | 113,857 | +113,857 | 0.00 | 0.59 | +0.59 | buy |
| ROYAL BANK OF CANADA | 36,945 | 110,509 | +73,564 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 96,821 | 101,537 | +4,716 | 0.00 | 0.00 | -0.00 | buy |
| SEVEN GRAND MANAGERS, LLC | 50,000 | 100,000 | +50,000 | 0.14 | 0.22 | +0.09 | buy |
| West Family Investments, Inc. | 87,773 | 87,773 | 0 | 0.66 | 0.60 | -0.06 | hold |
| BANK OF AMERICA CORP /DE/ | 64,981 | 86,738 | +21,757 | 0.00 | 0.00 | +0.00 | buy |
| Ghisallo Capital Management LLC | 75,000 | 75,000 | 0 | 0.08 | 0.10 | +0.02 | hold |
| MILLENNIUM MANAGEMENT LLC | 115,995 | 67,769 | -48,226 | 0.00 | 0.00 | -0.00 | sell |
| Burkehill Global Management, LP | 65,000 | 65,000 | 0 | 0.12 | 0.12 | +0.00 | hold |
| TD ASSET MANAGEMENT INC | 79,962 | 56,562 | -23,400 | 0.00 | 0.00 | -0.00 | sell |
| Brevan Howard Capital Management LP | 0 | 52,621 | +52,621 | 0.00 | 0.03 | +0.03 | buy |
| Bank of New York Mellon Corp | 0 | 48,653 | +48,653 | 0.00 | 0.00 | +0.00 | buy |
| Lisanti Capital Growth, LLC | 29,164 | 43,789 | +14,625 | 0.24 | 0.30 | +0.06 | buy |
| XTX Topco Ltd | 11,292 | 43,205 | +31,913 | 0.02 | 0.03 | +0.01 | buy |
| XXEC, Inc. | 29,832 | 41,920 | +12,088 | 0.85 | 1.22 | +0.37 | buy |
| Swiss National Bank | 0 | 41,100 | +41,100 | 0.00 | 0.00 | +0.00 | buy |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 39,704 | 36,877 | -2,827 | 0.00 | 0.00 | -0.00 | sell |
| NORGES BANK | 0 | 35,000 | +35,000 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0 | 32,773 | +32,773 | 0.00 | 0.00 | +0.00 | buy |
| BCWM, LLC | 0 | 31,139 | +31,139 | 0.00 | 0.27 | +0.27 | buy |
| BARCLAYS PLC | 16,718 | 30,336 | +13,618 | 0.00 | 0.00 | +0.00 | buy |
| TrueMark Investments, LLC | 27,264 | 26,506 | -758 | 0.16 | 0.15 | -0.01 | sell |
| Nuveen, LLC | 0 | 23,239 | +23,239 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 0 | 21,488 | +21,488 | 0.00 | 0.00 | +0.00 | buy |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 0 | 20,693 | +20,693 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 0 | 20,054 | +20,054 | 0.00 | 0.00 | +0.00 | buy |
| Quent Capital, LLC | 0 | 20,000 | +20,000 | 0.00 | 0.04 | +0.04 | buy |
| D. E. Shaw & Co., Inc. | 10,030 | 18,513 | +8,483 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 1,761 | 17,718 | +15,957 | 0.00 | 0.00 | +0.00 | buy |
| BRANDYWINE MANAGERS, LLC | 16,774 | 16,774 | 0 | 0.54 | 0.24 | -0.30 | hold |
| Legato Capital Management LLC | 7,215 | 16,180 | +8,965 | 0.03 | 0.04 | +0.01 | buy |
| Sandia Investment Management LP | 7,500 | 15,917 | +8,417 | 0.75 | 1.16 | +0.40 | buy |
| Perpetual Ltd | 0 | 15,741 | +15,741 | 0.00 | 0.01 | +0.01 | buy |
| SEI INVESTMENTS CO | 9,008 | 15,153 | +6,145 | 0.00 | 0.00 | +0.00 | buy |
| DEUTSCHE BANK AG\ | 0 | 13,844 | +13,844 | 0.00 | 0.00 | +0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 0 | 11,309 | +11,309 | 0.00 | 0.01 | +0.01 | buy |
| MetLife Investment Management, LLC | 0 | 11,035 | +11,035 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 0 | 10,715 | +10,715 | 0.00 | 0.00 | +0.00 | buy |
| STIFEL FINANCIAL CORP | 0 | 10,576 | +10,576 | 0.00 | 0.00 | +0.00 | buy |
| THRIVENT FINANCIAL FOR LUTHERANS | 0 | 8,610 | +8,610 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 8,600 | +8,600 | 0.00 | 0.00 | +0.00 | buy |
| CONNABLE OFFICE INC | 0 | 7,552 | +7,552 | 0.00 | 0.02 | +0.02 | buy |
| STALEY CAPITAL ADVISERS INC | 0 | 7,000 | +7,000 | 0.00 | 0.01 | +0.01 | buy |
| KLP KAPITALFORVALTNING AS | 0 | 4,500 | +4,500 | 0.00 | 0.00 | +0.00 | buy |
| Police & Firemen's Retirement System of New Jersey | 0 | 4,490 | +4,490 | 0.00 | 0.00 | +0.00 | buy |
| STRS OHIO | 0 | 3,400 | +3,400 | 0.00 | 0.00 | +0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 119,289 | 3,100 | -116,189 | 0.01 | 0.00 | -0.01 | sell |
| Caitong International Asset Management Co., Ltd | 0 | 2,479 | +2,479 | 0.00 | 0.02 | +0.02 | buy |
| CITIGROUP INC | 0 | 2,445 | +2,445 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 0 | 1,576 | +1,576 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 0 | 1,538 | +1,538 | 0.00 | 0.00 | +0.00 | buy |
| AMALGAMATED BANK | 0 | 610 | +610 | 0.00 | 0.00 | +0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 600 | 600 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Sterling Capital Management LLC | 0 | 597 | +597 | 0.00 | 0.00 | +0.00 | buy |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0 | 490 | +490 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 459 | +459 | 0.00 | 0.00 | +0.00 | buy |
| COMERICA BANK | 192 | 351 | +159 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 334 | 334 | 0 | 0.00 | 0.00 | -0.00 | hold |
| FNY Investment Advisers, LLC | 0 | 290 | +290 | 0.00 | 0.00 | +0.00 | buy |
| Center for Financial Planning, Inc. | 0 | 268 | +268 | 0.00 | 0.00 | +0.00 | buy |