| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Point72 Asset Management, L.P. | 523,751 | 1,072,418 | +548,667 | 0.01 | 0.01 | -0.01 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 1,532,313 | 1,946,134 | +413,821 | 0.04 | 0.02 | -0.03 | buy |
| BANK OF AMERICA CORP /DE/ | 0 | 336,399 | +336,399 | 0.00 | 0.00 | +0.00 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 360,476 | 685,198 | +324,722 | 0.01 | 0.01 | -0.01 | buy |
| Nantahala Capital Management, LLC | 266,613 | 530,713 | +264,100 | 0.19 | 0.12 | -0.06 | buy |
| ICONIQ Capital, LLC | 1,016,864 | 1,266,563 | +249,699 | 0.16 | 0.06 | -0.09 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 461,600 | 702,600 | +241,000 | 0.01 | 0.00 | -0.00 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,139,527 | 1,325,707 | +186,180 | 0.02 | 0.01 | -0.01 | buy |
| DIMENSIONAL FUND ADVISORS LP | 521,237 | 683,543 | +162,306 | 0.00 | 0.00 | -0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 78,085 | 205,833 | +127,748 | 0.06 | 0.05 | -0.01 | buy |
| Cubist Systematic Strategies, LLC | 0 | 122,931 | +122,931 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 118,819 | +118,819 | 0.00 | 0.00 | +0.00 | buy |
| MORGAN STANLEY | 339,238 | 453,833 | +114,595 | 0.00 | 0.00 | -0.00 | buy |
| TANG CAPITAL MANAGEMENT LLC | 0 | 100,000 | +100,000 | 0.00 | 0.02 | +0.02 | buy |
| NORTHERN TRUST CORP | 269,597 | 354,754 | +85,157 | 0.00 | 0.00 | -0.00 | buy |
| FEDERATED HERMES, INC. | 0 | 84,006 | +84,006 | 0.00 | 0.00 | +0.00 | buy |
| Ikarian Capital, LLC | 576,166 | 649,534 | +73,368 | 1.64 | 0.59 | -1.04 | buy |
| AQR CAPITAL MANAGEMENT LLC | 0 | 66,994 | +66,994 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 38,624 | 98,162 | +59,538 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 49,406 | 106,664 | +57,258 | 0.00 | 0.00 | -0.00 | buy |
| STATE OF WISCONSIN INVESTMENT BOARD | 21,443 | 73,868 | +52,425 | 0.00 | 0.00 | -0.00 | buy |
| XTX Topco Ltd | 0 | 45,089 | +45,089 | 0.00 | 0.01 | +0.01 | buy |
| Boxer Capital Management, LLC | 1,000,000 | 1,035,000 | +35,000 | 0.85 | 0.87 | +0.03 | buy |
| Dynamic Technology Lab Private Ltd | 0 | 33,679 | +33,679 | 0.00 | 0.01 | +0.01 | buy |
| Graham Capital Management, L.P. | 0 | 33,339 | +33,339 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 29,602 | +29,602 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 220,532 | 245,546 | +25,014 | 0.00 | 0.00 | -0.00 | buy |
| Aries Wealth Management | 0 | 25,000 | +25,000 | 0.00 | 0.02 | +0.02 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 768,694 | 793,593 | +24,899 | 0.00 | 0.00 | -0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 24,595 | +24,595 | 0.00 | 0.00 | +0.00 | buy |
| BOOTHBAY FUND MANAGEMENT, LLC | 157,858 | 179,619 | +21,761 | 0.05 | 0.02 | -0.03 | buy |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 14,759 | 34,340 | +19,581 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 2,535 | 21,039 | +18,504 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 831,169 | 849,249 | +18,080 | 0.00 | 0.00 | -0.00 | buy |
| Walleye Capital LLC | 0 | 17,628 | +17,628 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 59,967 | 75,042 | +15,075 | 0.00 | 0.00 | -0.00 | buy |
| HSBC HOLDINGS PLC | 28,967 | 41,569 | +12,602 | 0.00 | 0.00 | -0.00 | buy |
| Squarepoint Ops LLC | 0 | 10,541 | +10,541 | 0.00 | 0.00 | +0.00 | buy |
| Vontobel Holding Ltd. | 0 | 10,000 | +10,000 | 0.00 | 0.00 | +0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 94,585 | 102,009 | +7,424 | 0.00 | 0.00 | -0.00 | buy |
| VANGUARD GROUP INC | 1,682,209 | 1,688,815 | +6,606 | 0.00 | 0.00 | -0.00 | buy |
| DEUTSCHE BANK AG\ | 67,546 | 73,564 | +6,018 | 0.00 | 0.00 | -0.00 | buy |
| Farther Finance Advisors, LLC | 0 | 6,006 | +6,006 | 0.00 | 0.00 | +0.00 | buy |
| US BANCORP \DE\ | 4,006 | 9,282 | +5,276 | 0.00 | 0.00 | -0.00 | buy |
| TWO SIGMA ADVISERS, LP | 284,200 | 289,200 | +5,000 | 0.01 | 0.00 | -0.00 | buy |
| BlackRock, Inc. | 3,727,531 | 3,731,879 | +4,348 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 857 | 3,082 | +2,225 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 1,709 | 3,659 | +1,950 | 0.00 | 0.00 | -0.00 | buy |
| MACQUARIE GROUP LTD | 0 | 1,636 | +1,636 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 22,269 | 23,203 | +934 | 0.00 | 0.00 | -0.00 | buy |
| COLDSTREAM CAPITAL MANAGEMENT INC | 0 | 924 | +924 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 18,563 | 19,421 | +858 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 51,469 | 52,274 | +805 | 0.00 | 0.00 | -0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 11,818 | 12,379 | +561 | 0.00 | 0.00 | -0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 217 | 643 | +426 | 0.00 | 0.00 | +0.00 | buy |
| Physician Wealth Advisors, Inc. | 0 | 305 | +305 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 22 | +22 | 0.00 | 0.00 | +0.00 | buy |
| True Wealth Design, LLC | 0 | 13 | +13 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 2,568 | 2,568 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 2,364 | 2,364 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BAKER BROS. ADVISORS LP | 17,310,490 | 17,310,490 | 0 | 1.84 | 0.54 | -1.30 | hold |
| Board of Trustees of The Leland Stanford Junior University | 691,767 | 691,767 | 0 | 0.59 | 0.16 | -0.42 | hold |
| Bruce & Co., Inc. | 323,000 | 323,000 | 0 | 1.03 | 0.29 | -0.74 | hold |
| Avion Wealth | 352 | 352 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Cornerstone Planning Group LLC | 210 | 210 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TCG Crossover Management, LLC | 1,145,538 | 1,145,538 | 0 | 1.11 | 0.44 | -0.68 | hold |
| Continuum Advisory, LLC | 14,852 | 14,852 | 0 | 0.02 | 0.01 | -0.01 | hold |
| Activest Wealth Management | 1,001 | 1,001 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Police & Firemen's Retirement System of New Jersey | 6,254 | 6,254 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Legal & General Group Plc | 2,747 | 2,747 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MEEDER ASSET MANAGEMENT INC | 15,137 | 15,137 | 0 | 0.01 | 0.00 | -0.01 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 1,631 | 1,631 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 1,154 | 1,154 | 0 | 0.00 | 0.00 | -0.00 | hold |
| WEST PACES ADVISORS INC. | 12 | 0 | -12 | 0.00 | 0.00 | -0.00 | sell |
| SBI Securities Co., Ltd. | 20 | 1 | -19 | 0.00 | 0.00 | -0.00 | sell |
| GAMMA Investing LLC | 68 | 0 | -68 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 169 | 0 | -169 | 0.00 | 0.00 | -0.00 | sell |
| Corebridge Financial, Inc. | 16,221 | 15,984 | -237 | 0.00 | 0.00 | -0.00 | sell |
| Cerity Partners LLC | 16,759 | 16,513 | -246 | 0.00 | 0.00 | +0.00 | sell |
| Sterling Capital Management LLC | 1,046 | 586 | -460 | 0.00 | 0.00 | -0.00 | sell |
| Eagle Bay Advisors LLC | 582 | 0 | -582 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 98,102 | 97,357 | -745 | 0.00 | 0.00 | -0.00 | sell |
| JGP Global Gestao de Recursos Ltda. | 12,950 | 10,904 | -2,046 | 0.29 | 0.02 | -0.27 | sell |
| CITIGROUP INC | 25,231 | 22,771 | -2,460 | 0.00 | 0.00 | -0.00 | sell |
| PNC FINANCIAL SERVICES GROUP, INC. | 2,988 | 0 | -2,988 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 5,004 | 2,004 | -3,000 | 0.00 | 0.00 | -0.00 | sell |
| LJI Wealth Management, LLC | 13,100 | 10,100 | -3,000 | 0.03 | 0.01 | -0.02 | sell |
| GROUP ONE TRADING LLC | 3,935 | 47 | -3,888 | 0.00 | 0.00 | -0.00 | sell |
| ALLIANCEBERNSTEIN L.P. | 71,470 | 66,610 | -4,860 | 0.00 | 0.00 | -0.00 | sell |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 269,654 | 263,370 | -6,284 | 0.00 | 0.00 | -0.00 | sell |
| Headlands Technologies LLC | 9,070 | 2,268 | -6,802 | 0.01 | 0.00 | -0.01 | sell |
| BARCLAYS PLC | 73,927 | 65,771 | -8,156 | 0.00 | 0.00 | -0.00 | sell |
| OSAIC HOLDINGS, INC. | 10,638 | 0 | -10,638 | 0.00 | 0.00 | -0.00 | sell |
| FOX RUN MANAGEMENT, L.L.C. | 11,841 | 0 | -11,841 | 0.02 | 0.00 | -0.02 | sell |
| PRUDENTIAL FINANCIAL INC | 13,708 | 0 | -13,708 | 0.00 | 0.00 | -0.00 | sell |
| PDT Partners, LLC | 13,759 | 0 | -13,759 | 0.01 | 0.00 | -0.01 | sell |
| Jump Financial, LLC | 14,737 | 0 | -14,737 | 0.00 | 0.00 | -0.00 | sell |
| RIA Advisory Group LLC | 118,546 | 100,476 | -18,070 | 0.40 | 0.09 | -0.31 | sell |
| SG Americas Securities, LLC | 20,684 | 0 | -20,684 | 0.00 | 0.00 | -0.00 | sell |
| MetLife Investment Management, LLC | 21,040 | 0 | -21,040 | 0.00 | 0.00 | -0.00 | sell |