| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| ACADIAN ASSET MANAGEMENT LLC | 1,722,890 | 1,965,449 | +242,559 | 0.03 | 0.01 | -0.02 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 525,650 | 699,158 | +173,508 | 0.01 | 0.01 | -0.01 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 581,400 | 708,800 | +127,400 | 0.00 | 0.00 | -0.00 | buy |
| PANAGORA ASSET MANAGEMENT INC | 0 | 88,030 | +88,030 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 69,357 | 124,411 | +55,054 | 0.00 | 0.00 | -0.00 | buy |
| STATE STREET CORP | 747,495 | 801,923 | +54,428 | 0.00 | 0.00 | -0.00 | buy |
| Squarepoint Ops LLC | 0 | 53,988 | +53,988 | 0.00 | 0.00 | +0.00 | buy |
| MARSHALL WACE, LLP | 117,495 | 166,425 | +48,930 | 0.00 | 0.00 | -0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 41,008 | 79,108 | +38,100 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 722,961 | 755,957 | +32,996 | 0.00 | 0.00 | -0.00 | buy |
| SEI INVESTMENTS CO | 113,158 | 143,841 | +30,683 | 0.00 | 0.00 | -0.00 | buy |
| Graham Capital Management, L.P. | 0 | 29,682 | +29,682 | 0.00 | 0.00 | +0.00 | buy |
| Atom Investors LP | 171,495 | 199,535 | +28,040 | 0.11 | 0.05 | -0.07 | buy |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 114,200 | 139,200 | +25,000 | 0.01 | 0.01 | -0.00 | buy |
| HRT FINANCIAL LP | 0 | 24,098 | +24,098 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 0 | 19,400 | +19,400 | 0.00 | 0.00 | +0.00 | buy |
| PDT Partners, LLC | 0 | 16,310 | +16,310 | 0.00 | 0.00 | +0.00 | buy |
| MEEDER ASSET MANAGEMENT INC | 0 | 15,137 | +15,137 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 263,276 | 276,550 | +13,274 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 2,423 | 14,637 | +12,214 | 0.00 | 0.00 | +0.00 | buy |
| OXFORD ASSET MANAGEMENT LLP | 0 | 11,695 | +11,695 | 0.00 | 0.03 | +0.03 | buy |
| Vanguard Personalized Indexing Management, LLC | 0 | 10,351 | +10,351 | 0.00 | 0.00 | +0.00 | buy |
| Walleye Capital LLC | 0 | 10,171 | +10,171 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 10,037 | +10,037 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 0 | 9,046 | +9,046 | 0.00 | 0.00 | +0.00 | buy |
| AMERICAN CENTURY COMPANIES INC | 45,853 | 54,323 | +8,470 | 0.00 | 0.00 | -0.00 | buy |
| BANK OF AMERICA CORP /DE/ | 287,014 | 295,156 | +8,142 | 0.00 | 0.00 | -0.00 | buy |
| WELLS FARGO & COMPANY/MN | 18,060 | 25,335 | +7,275 | 0.00 | 0.00 | -0.00 | buy |
| Point72 (DIFC) Ltd | 0 | 7,108 | +7,108 | 0.00 | 0.00 | +0.00 | buy |
| ALLIANCEBERNSTEIN L.P. | 66,030 | 71,470 | +5,440 | 0.00 | 0.00 | -0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 5,309 | +5,309 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 154,109 | 158,984 | +4,875 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 1,861 | 6,690 | +4,829 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 44,916 | 47,616 | +2,700 | 0.01 | 0.00 | -0.01 | buy |
| HSBC HOLDINGS PLC | 40,326 | 42,171 | +1,845 | 0.00 | 0.00 | -0.00 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 46,262 | 47,869 | +1,607 | 0.00 | 0.00 | -0.00 | buy |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | 1,338 | +1,338 | 0.00 | 0.00 | +0.00 | buy |
| Activest Wealth Management | 0 | 1,001 | +1,001 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 1,654,448 | 1,655,439 | +991 | 0.00 | 0.00 | -0.00 | buy |
| CITIGROUP INC | 6,606 | 7,429 | +823 | 0.00 | 0.00 | -0.00 | buy |
| Acuitas Investments, LLC | 131,803 | 132,502 | +699 | 0.35 | 0.17 | -0.18 | buy |
| RHUMBLINE ADVISERS | 55,925 | 56,511 | +586 | 0.00 | 0.00 | -0.00 | buy |
| NEW YORK STATE COMMON RETIREMENT FUND | 1,591 | 1,631 | +40 | 0.00 | 0.00 | -0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 16 | 48 | +32 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 7 | 21 | +14 | 0.00 | 0.00 | 0.00 | buy |
| INNEALTA CAPITAL, LLC | 0 | 10 | +10 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 7 | +7 | 0.00 | 0.00 | +0.00 | buy |
| MATHER GROUP, LLC. | 0 | 4 | +4 | 0.00 | 0.00 | +0.00 | buy |
| Ameritas Investment Partners, Inc. | 2,568 | 2,568 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BAKER BROS. ADVISORS LP | 17,310,490 | 17,310,490 | 0 | 1.14 | 0.52 | -0.62 | hold |
| Board of Trustees of The Leland Stanford Junior University | 691,767 | 691,767 | 0 | 0.32 | 0.11 | -0.21 | hold |
| Janney Montgomery Scott LLC | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Bruce & Co., Inc. | 423,000 | 423,000 | 0 | 0.74 | 0.33 | -0.41 | hold |
| Marquette Asset Management, LLC | 23,930 | 23,930 | 0 | 0.02 | 0.01 | -0.01 | hold |
| JGP Global Gestao de Recursos Ltda. | 14,957 | 14,957 | 0 | 0.05 | 0.04 | -0.01 | hold |
| BOOTHBAY FUND MANAGEMENT, LLC | 129,438 | 129,438 | 0 | 0.02 | 0.01 | -0.01 | hold |
| ICONIQ Capital, LLC | 1,016,864 | 1,016,864 | 0 | 0.09 | 0.05 | -0.04 | hold |
| Vontobel Holding Ltd. | 11,000 | 11,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Global Retirement Partners, LLC | 6 | 6 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ikarian Capital, LLC | 476,586 | 476,586 | 0 | 0.68 | 0.35 | -0.33 | hold |
| Nan Fung Group Holdings Ltd | 31,922 | 31,922 | 0 | 0.16 | 0.08 | -0.08 | hold |
| Avion Wealth | 352 | 352 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TCG Crossover Management, LLC | 899,999 | 899,999 | 0 | 0.37 | 0.22 | -0.15 | hold |
| Continuum Advisory, LLC | 14,852 | 14,852 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Eagle Bay Advisors LLC | 582 | 582 | 0 | 0.00 | 0.00 | -0.00 | hold |
| LJI Wealth Management, LLC | 14,100 | 14,100 | 0 | 0.02 | 0.01 | -0.01 | hold |
| WEST PACES ADVISORS INC. | 12 | 12 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Erste Asset Management GmbH | 11,300 | 11,300 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Legal & General Group Plc | 2,747 | 2,747 | 0 | 0.00 | 0.00 | -0.00 | hold |
| STRS OHIO | 28,800 | 28,800 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 1,154 | 1,154 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Colonial Trust Advisors | 4 | 0 | -4 | 0.00 | 0.00 | -0.00 | sell |
| Avior Wealth Management, LLC | 13 | 0 | -13 | 0.00 | 0.00 | -0.00 | sell |
| Capital Advisors, Ltd. LLC | 145 | 0 | -145 | 0.00 | 0.00 | -0.00 | sell |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 5,514 | 5,199 | -315 | 0.00 | 0.00 | -0.00 | sell |
| METROPOLITAN LIFE INSURANCE CO/NY | 699 | 0 | -699 | 0.00 | 0.00 | -0.00 | sell |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 3,261 | 2,364 | -897 | 0.00 | 0.00 | -0.00 | sell |
| GAMMA Investing LLC | 1,061 | 0 | -1,061 | 0.00 | 0.00 | -0.00 | sell |
| DEUTSCHE BANK AG\ | 60,585 | 58,094 | -2,491 | 0.00 | 0.00 | -0.00 | sell |
| Bank of New York Mellon Corp | 120,095 | 117,447 | -2,648 | 0.00 | 0.00 | -0.00 | sell |
| ZACKS INVESTMENT MANAGEMENT | 23,173 | 15,015 | -8,158 | 0.00 | 0.00 | -0.00 | sell |
| OSAIC HOLDINGS, INC. | 8,245 | 0 | -8,245 | 0.00 | 0.00 | -0.00 | sell |
| Catalyst Funds Management Pty Ltd | 8,500 | 0 | -8,500 | 0.01 | 0.00 | -0.01 | sell |
| Headlands Technologies LLC | 9,537 | 0 | -9,537 | 0.01 | 0.00 | -0.01 | sell |
| MetLife Investment Management, LLC | 10,366 | 0 | -10,366 | 0.00 | 0.00 | -0.00 | sell |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 10,595 | 0 | -10,595 | 0.00 | 0.00 | -0.00 | sell |
| VOYA INVESTMENT MANAGEMENT LLC | 10,966 | 0 | -10,966 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 59,418 | 48,131 | -11,287 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 11,294 | 0 | -11,294 | 0.00 | 0.00 | -0.00 | sell |
| AMERIPRISE FINANCIAL INC | 45,263 | 33,628 | -11,635 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 256,919 | 244,519 | -12,400 | 0.00 | 0.00 | -0.00 | sell |
| THRIVENT FINANCIAL FOR LUTHERANS | 12,800 | 0 | -12,800 | 0.00 | 0.00 | -0.00 | sell |
| Cubist Systematic Strategies, LLC | 112,678 | 99,335 | -13,343 | 0.01 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 16,090 | 2,697 | -13,393 | 0.00 | 0.00 | -0.00 | sell |
| LOS ANGELES CAPITAL MANAGEMENT LLC | 132,529 | 119,129 | -13,400 | 0.00 | 0.00 | -0.00 | sell |
| Mirae Asset Global Investments Co., Ltd. | 13,932 | 0 | -13,932 | 0.00 | 0.00 | -0.00 | sell |
| Susquehanna Portfolio Strategies, LLC | 102,369 | 88,016 | -14,353 | 0.01 | 0.01 | -0.00 | sell |
| XTX Topco Ltd | 14,402 | 0 | -14,402 | 0.01 | 0.00 | -0.01 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 14,486 | 0 | -14,486 | 0.00 | 0.00 | -0.00 | sell |
| Cerity Partners LLC | 15,116 | 0 | -15,116 | 0.00 | 0.00 | -0.00 | sell |