| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| FMR LLC | 0 | 3,906,143 | +3,906,143 | 0.00 | 0.00 | +0.00 | buy |
| Redmile Group, LLC | 0 | 3,879,415 | +3,879,415 | 0.00 | 1.48 | +1.48 | buy |
| EcoR1 Capital, LLC | 0 | 3,879,415 | +3,879,415 | 0.00 | 1.08 | +1.08 | buy |
| JANUS HENDERSON GROUP PLC | 0 | 1,391,471 | +1,391,471 | 0.00 | 0.01 | +0.01 | buy |
| VANGUARD GROUP INC | 396,329 | 1,740,026 | +1,343,697 | 0.00 | 0.00 | +0.00 | buy |
| Avidity Partners Management LP | 0 | 1,333,479 | +1,333,479 | 0.00 | 0.55 | +0.55 | buy |
| Woodline Partners LP | 0 | 922,892 | +922,892 | 0.00 | 0.11 | +0.11 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 173,630 | 1,051,222 | +877,592 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 84,708 | 320,838 | +236,130 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 10 | 203,548 | +203,538 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asset Management, L.P. | 545,919 | 682,619 | +136,700 | 0.02 | 0.02 | +0.01 | buy |
| JANE STREET GROUP, LLC | 0 | 103,475 | +103,475 | 0.00 | 0.00 | +0.00 | buy |
| Laurion Capital Management LP | 0 | 102,954 | +102,954 | 0.00 | 0.04 | +0.04 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 32,400 | 121,500 | +89,100 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 16,465 | 100,228 | +83,763 | 0.00 | 0.00 | +0.00 | buy |
| BARCLAYS PLC | 0 | 82,455 | +82,455 | 0.00 | 0.00 | +0.00 | buy |
| Cerity Partners LLC | 0 | 61,346 | +61,346 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 61,043 | +61,043 | 0.00 | 0.00 | +0.00 | buy |
| ExodusPoint Capital Management, LP | 0 | 33,142 | +33,142 | 0.00 | 0.00 | +0.00 | buy |
| BALYASNY ASSET MANAGEMENT L.P. | 0 | 28,649 | +28,649 | 0.00 | 0.00 | +0.00 | buy |
| 683 Capital Management, LLC | 0 | 27,149 | +27,149 | 0.00 | 0.03 | +0.03 | buy |
| Man Group plc | 0 | 23,490 | +23,490 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 0 | 18,302 | +18,302 | 0.00 | 0.00 | +0.00 | buy |
| Sterling Investment Advisors, Ltd. | 0 | 16,965 | +16,965 | 0.00 | 0.06 | +0.06 | buy |
| Jump Financial, LLC | 0 | 16,100 | +16,100 | 0.00 | 0.01 | +0.01 | buy |
| Bank of New York Mellon Corp | 0 | 15,844 | +15,844 | 0.00 | 0.00 | +0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 0 | 13,000 | +13,000 | 0.00 | 0.00 | +0.00 | buy |
| MIRABELLA FINANCIAL SERVICES LLP | 0 | 12,200 | +12,200 | 0.00 | 0.02 | +0.02 | buy |
| Cubist Systematic Strategies, LLC | 299 | 10,246 | +9,947 | 0.00 | 0.00 | +0.00 | buy |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 25,129 | 34,827 | +9,698 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 0 | 7,700 | +7,700 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 29,091 | 36,018 | +6,927 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 29,591 | 30,591 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| ROYAL BANK OF CANADA | 28,556 | 29,484 | +928 | 0.00 | 0.00 | +0.00 | buy |
| FEDERATED HERMES, INC. | 0 | 87 | +87 | 0.00 | 0.00 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 127,280 | 127,280 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Prentice Capital Management, LP | 112,131 | 112,131 | 0 | 2.88 | 2.79 | -0.09 | hold |
| Baldwin Investment Management, LLC | 25,394 | 25,394 | 0 | 0.04 | 0.04 | +0.01 | hold |
| Magnus Financial Group LLC | 25,759 | 25,759 | 0 | 0.03 | 0.04 | +0.00 | hold |
| Newbridge Financial Services Group, Inc. | 225 | 225 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Farther Finance Advisors, LLC | 100 | 100 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MB, LEVIS & ASSOCIATES, LLC | 2,373 | 2,373 | 0 | 0.01 | 0.01 | +0.00 | hold |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | 53,746 | 53,746 | 0 | 0.00 | 0.00 | +0.00 | hold |
| DIMENSIONAL FUND ADVISORS LP | 15,433 | 14,054 | -1,379 | 0.00 | 0.00 | +0.00 | sell |
| HighTower Advisors, LLC | 18,818 | 16,818 | -2,000 | 0.00 | 0.00 | +0.00 | sell |
| Dorsey Wright & Associates | 3,100 | 0 | -3,100 | 0.01 | 0.00 | -0.01 | sell |
| CITADEL ADVISORS LLC | 7,493 | 0 | -7,493 | 0.00 | 0.00 | -0.00 | sell |
| Wealth Architects, LLC | 11,110 | 0 | -11,110 | 0.02 | 0.00 | -0.02 | sell |
| SIMPLEX TRADING, LLC | 14,939 | 2,717 | -12,222 | 0.00 | 0.00 | -0.00 | sell |
| Schonfeld Strategic Advisors LLC | 18,201 | 0 | -18,201 | 0.00 | 0.00 | -0.00 | sell |
| ACADIAN ASSET MANAGEMENT LLC | 49,712 | 19,005 | -30,707 | 0.00 | 0.00 | -0.00 | sell |
| BANK OF MONTREAL /CAN/ | 92,593 | 0 | -92,593 | 0.00 | 0.00 | -0.00 | sell |
| Alpine Global Management, LLC | 365,971 | 192,333 | -173,638 | 0.70 | 0.56 | -0.14 | sell |