| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Blue Water Life Science Advisors, LP | 0 | 2,145,145 | +2,145,145 | 0.00 | 9.66 | +9.66 | buy |
| Sumitomo Mitsui Trust Group, Inc. | 6,899,631 | 7,733,884 | +834,253 | 0.02 | 0.03 | +0.01 | buy |
| Nikko Asset Management Americas, Inc. | 6,919,778 | 7,733,884 | +814,106 | 0.29 | 0.45 | +0.16 | buy |
| GOLDMAN SACHS GROUP INC | 1,048,012 | 1,749,147 | +701,135 | 0.00 | 0.00 | +0.00 | buy |
| Clearline Capital LP | 0 | 614,593 | +614,593 | 0.00 | 0.28 | +0.28 | buy |
| MORGAN STANLEY | 516,460 | 1,048,132 | +531,672 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asset Management, L.P. | 0 | 495,492 | +495,492 | 0.00 | 0.01 | +0.01 | buy |
| DRIEHAUS CAPITAL MANAGEMENT LLC | 0 | 435,294 | +435,294 | 0.00 | 0.02 | +0.02 | buy |
| VANGUARD GROUP INC | 10,226,911 | 10,639,440 | +412,529 | 0.00 | 0.00 | +0.00 | buy |
| Rubric Capital Management LP | 14,000,000 | 14,400,000 | +400,000 | 1.34 | 1.21 | -0.13 | buy |
| Cubist Systematic Strategies, LLC | 0 | 299,281 | +299,281 | 0.00 | 0.02 | +0.02 | buy |
| Cerity Partners LLC | 437,484 | 694,417 | +256,933 | 0.00 | 0.01 | +0.00 | buy |
| Pier Capital, LLC | 1,055,299 | 1,275,885 | +220,586 | 0.57 | 0.92 | +0.35 | buy |
| ARK Investment Management LLC | 11,412,000 | 11,601,134 | +189,134 | 0.37 | 0.54 | +0.18 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 177,689 | +177,689 | 0.00 | 0.00 | +0.00 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0 | 143,679 | +143,679 | 0.00 | 0.00 | +0.00 | buy |
| MILLENNIUM MANAGEMENT LLC | 9,262,341 | 9,400,573 | +138,232 | 0.03 | 0.04 | +0.01 | buy |
| BARCLAYS PLC | 92,241 | 230,177 | +137,936 | 0.00 | 0.00 | +0.00 | buy |
| FMR LLC | 115,601 | 233,566 | +117,965 | 0.00 | 0.00 | +0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 65,745 | 165,274 | +99,529 | 0.01 | 0.02 | +0.01 | buy |
| ESSEX INVESTMENT MANAGEMENT CO LLC | 623,825 | 718,656 | +94,831 | 0.42 | 0.64 | +0.22 | buy |
| AQR CAPITAL MANAGEMENT LLC | 182,076 | 261,964 | +79,888 | 0.00 | 0.00 | +0.00 | buy |
| Russell Investments Group, Ltd. | 2,762 | 78,831 | +76,069 | 0.00 | 0.00 | +0.00 | buy |
| US BANCORP \DE\ | 92,041 | 163,106 | +71,065 | 0.00 | 0.00 | +0.00 | buy |
| PDT Partners, LLC | 215,004 | 280,382 | +65,378 | 0.07 | 0.13 | +0.05 | buy |
| JENNISON ASSOCIATES LLC | 177,623 | 231,531 | +53,908 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 52,360 | +52,360 | 0.00 | 0.00 | +0.00 | buy |
| DIMENSIONAL FUND ADVISORS LP | 1,369,097 | 1,420,995 | +51,898 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 2,502,900 | 2,551,785 | +48,885 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 48,165 | +48,165 | 0.00 | 0.02 | +0.02 | buy |
| CITIGROUP INC | 61,006 | 108,541 | +47,535 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 10,299 | 55,820 | +45,521 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 44,969 | +44,969 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 927,881 | 963,532 | +35,651 | 0.00 | 0.00 | +0.00 | buy |
| Dynamic Technology Lab Private Ltd | 0 | 34,583 | +34,583 | 0.00 | 0.02 | +0.02 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 34,293 | +34,293 | 0.00 | 0.00 | +0.00 | buy |
| Jump Financial, LLC | 86,835 | 120,020 | +33,185 | 0.01 | 0.01 | +0.01 | buy |
| AMERIPRISE FINANCIAL INC | 50,909 | 82,411 | +31,502 | 0.00 | 0.00 | +0.00 | buy |
| Aristotle Atlantic Partners, LLC | 2,974,188 | 3,001,201 | +27,013 | 0.35 | 0.48 | +0.13 | buy |
| AMERICAN CENTURY COMPANIES INC | 45,562 | 71,165 | +25,603 | 0.00 | 0.00 | +0.00 | buy |
| Point72 (DIFC) Ltd | 0 | 19,637 | +19,637 | 0.00 | 0.01 | +0.01 | buy |
| SG Americas Securities, LLC | 21,667 | 41,145 | +19,478 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 151,800 | 169,400 | +17,600 | 0.00 | 0.00 | +0.00 | buy |
| UBS Group AG | 56,631 | 73,151 | +16,520 | 0.00 | 0.00 | +0.00 | buy |
| Centiva Capital, LP | 0 | 15,635 | +15,635 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 12,154 | +12,154 | 0.00 | 0.00 | +0.00 | buy |
| ALGERT GLOBAL LLC | 64,323 | 76,323 | +12,000 | 0.01 | 0.01 | +0.00 | buy |
| China Universal Asset Management Co., Ltd. | 17,314 | 28,364 | +11,050 | 0.01 | 0.02 | +0.01 | buy |
| TOWNSQUARE CAPITAL LLC | 0 | 11,018 | +11,018 | 0.00 | 0.00 | +0.00 | buy |
| Amundi | 0 | 11,001 | +11,001 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA ADVISERS, LP | 0 | 10,400 | +10,400 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 906,481 | 916,743 | +10,262 | 0.00 | 0.00 | +0.00 | buy |
| ASHTON THOMAS SECURITIES, LLC | 0 | 6,685 | +6,685 | 0.00 | 0.01 | +0.01 | buy |
| B. Riley Wealth Advisors, Inc. | 13,500 | 20,000 | +6,500 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 56,945 | 63,291 | +6,346 | 0.00 | 0.00 | +0.00 | buy |
| ProShare Advisors LLC | 24,312 | 30,600 | +6,288 | 0.00 | 0.00 | +0.00 | buy |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 19,750 | 25,576 | +5,826 | 0.01 | 0.01 | +0.01 | buy |
| Corient Private Wealth LLC | 81,744 | 87,005 | +5,261 | 0.00 | 0.00 | +0.00 | buy |
| JTC Employer Solutions Trustee Ltd | 0 | 5,109 | +5,109 | 0.00 | 0.00 | +0.00 | buy |
| Vontobel Holding Ltd. | 13,000 | 17,000 | +4,000 | 0.00 | 0.00 | +0.00 | buy |
| HSBC HOLDINGS PLC | 32,250 | 36,111 | +3,861 | 0.00 | 0.00 | +0.00 | buy |
| Neuberger Berman Group LLC | 105,203 | 108,526 | +3,323 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 6,441 | 9,319 | +2,878 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 11,665 | 14,214 | +2,549 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 47,406 | 49,324 | +1,918 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 1,619 | +1,619 | 0.00 | 0.00 | +0.00 | buy |
| CAPTRUST FINANCIAL ADVISORS | 11,313 | 12,930 | +1,617 | 0.00 | 0.00 | +0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 22,325 | 23,829 | +1,504 | 0.00 | 0.00 | +0.00 | buy |
| Wilmington Savings Fund Society, FSB | 0 | 1,450 | +1,450 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 14,566 | 15,791 | +1,225 | 0.00 | 0.00 | +0.00 | buy |
| Catalyst Funds Management Pty Ltd | 900 | 2,000 | +1,100 | 0.00 | 0.00 | +0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 158,807 | 159,823 | +1,016 | 0.00 | 0.00 | +0.00 | buy |
| Legal & General Group Plc | 9,821 | 10,832 | +1,011 | 0.00 | 0.00 | +0.00 | buy |
| Mirae Asset Global Investments Co., Ltd. | 4,400 | 5,334 | +934 | 0.00 | 0.00 | +0.00 | buy |
| EARNED WEALTH ADVISORS, LLC | 0 | 764 | +764 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 53,812 | 54,479 | +667 | 0.00 | 0.00 | +0.00 | buy |
| OSAIC HOLDINGS, INC. | 57,003 | 57,453 | +450 | 0.00 | 0.00 | +0.00 | buy |
| SIGNATUREFD, LLC | 4,119 | 4,507 | +388 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 515,384 | 515,772 | +388 | 0.02 | 0.03 | +0.01 | buy |
| Impact Partnership Wealth, LLC | 17,154 | 17,539 | +385 | 0.02 | 0.02 | +0.00 | buy |
| Hemington Wealth Management | 0 | 200 | +200 | 0.00 | 0.00 | 0.00 | buy |
| True Wealth Design, LLC | 0 | 195 | +195 | 0.00 | 0.00 | +0.00 | buy |
| ROTHSCHILD INVESTMENT LLC | 10,040 | 10,210 | +170 | 0.00 | 0.00 | +0.00 | buy |
| BOKF, NA | 0 | 116 | +116 | 0.00 | 0.00 | +0.00 | buy |
| Blue Trust, Inc. | 0 | 91 | +91 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 15,356 | 15,425 | +69 | 0.00 | 0.00 | +0.00 | buy |
| Smartleaf Asset Management LLC | 572 | 609 | +37 | 0.00 | 0.00 | +0.00 | buy |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0 | 24 | +24 | 0.00 | 0.00 | +0.00 | buy |
| MARTINGALE ASSET MANAGEMENT L P | 58,600 | 58,621 | +21 | 0.00 | 0.01 | +0.00 | buy |
| AVENIR CORP | 76,365 | 76,365 | 0 | 0.03 | 0.04 | +0.01 | hold |
| Ameritas Investment Partners, Inc. | 11,286 | 11,286 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 8,392 | 8,392 | 0 | 0.00 | 0.00 | +0.00 | hold |
| VIKING GLOBAL INVESTORS LP | 29,993,708 | 29,993,708 | 0 | 0.42 | 0.56 | +0.14 | hold |
| Manchester Capital Management LLC | 9,850 | 9,850 | 0 | 0.00 | 0.01 | +0.00 | hold |
| HighTower Advisors, LLC | 16,683 | 16,683 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Mesirow Financial Investment Management, Inc. | 18,715 | 18,715 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BROWN, LISLE/CUMMINGS, INC. | 200 | 200 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Asset Dedication, LLC | 1,231 | 1,231 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Daiwa Securities Group Inc. | 530 | 530 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Savant Capital, LLC | 34,220 | 34,220 | 0 | 0.00 | 0.00 | +0.00 | hold |