| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | 0 | 277,610 | +277,610 | 0.00 | 0.06 | +0.06 | buy |
| Woodline Partners LP | 0 | 258,766 | +258,766 | 0.00 | 0.01 | +0.01 | buy |
| VANGUARD GROUP INC | 53,570 | 152,775 | +99,205 | 0.00 | 0.00 | +0.00 | buy |
| ADAR1 Capital Management, LLC | 220,373 | 298,955 | +78,582 | 0.32 | 0.33 | +0.01 | buy |
| AIGH Capital Management LLC | 121,302 | 196,350 | +75,048 | 0.32 | 0.58 | +0.27 | buy |
| READYSTATE ASSET MANAGEMENT LP | 0 | 42,459 | +42,459 | 0.00 | 0.01 | +0.01 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 231,070 | 246,079 | +15,009 | 0.36 | 0.29 | -0.06 | buy |
| NORTHERN TRUST CORP | 0 | 10,399 | +10,399 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 47,642 | 54,833 | +7,191 | 0.00 | 0.00 | -0.00 | buy |
| Covestor Ltd | 969 | 1,140 | +171 | 0.00 | 0.00 | +0.00 | buy |
| Legacy Wealth Managment, LLC/ID | 10 | 25 | +15 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 300 | 300 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 98 | 98 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BAKER BROS. ADVISORS LP | 1,201,894 | 1,201,894 | 0 | 0.09 | 0.08 | -0.01 | hold |
| Cormorant Asset Management, LP | 603,027 | 603,027 | 0 | 0.23 | 0.26 | +0.03 | hold |
| Steward Partners Investment Advisory, LLC | 120 | 120 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SBI Securities Co., Ltd. | 8 | 8 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SR ONE CAPITAL MANAGEMENT, LP | 598,940 | 598,940 | 0 | 1.01 | 0.88 | -0.13 | hold |
| BlackRock, Inc. | 21,356 | 21,356 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CURIO WEALTH, LLC | 20 | 1 | -19 | 0.00 | 0.00 | -0.00 | sell |
| GROUP ONE TRADING LLC | 22 | 0 | -22 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 200 | 0 | -200 | 0.00 | 0.00 | -0.00 | sell |
| Compagnie Lombard Odier SCmA | 400 | 0 | -400 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 712 | 221 | -491 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 5,676 | 0 | -5,676 | 0.00 | 0.00 | -0.00 | sell |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 178,934 | 170,917 | -8,017 | 0.03 | 0.02 | -0.01 | sell |
| TWO SIGMA INVESTMENTS, LP | 11,877 | 0 | -11,877 | 0.00 | 0.00 | -0.00 | sell |
| Board of Trustees of The Leland Stanford Junior University | 21,127 | 0 | -21,127 | 0.01 | 0.00 | -0.01 | sell |
| MILLENNIUM MANAGEMENT LLC | 136,056 | 0 | -136,056 | 0.00 | 0.00 | -0.00 | sell |