| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | 266,613 | 891,335 | +624,722 | 0.03 | 0.08 | +0.05 | buy |
| SR ONE CAPITAL MANAGEMENT, LP | 0 | 443,661 | +443,661 | 0.00 | 0.98 | +0.98 | buy |
| ADAR1 Capital Management, LLC | 0 | 306,067 | +306,067 | 0.00 | 0.44 | +0.44 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 72,554 | 147,554 | +75,000 | 0.02 | 0.03 | +0.01 | buy |
| Virtu Financial LLC | 0 | 31,101 | +31,101 | 0.00 | 0.02 | +0.02 | buy |
| Sassicaia Capital Advisers LLC | 0 | 12,000 | +12,000 | 0.00 | 0.34 | +0.34 | buy |
| MILLENNIUM MANAGEMENT LLC | 133,403 | 142,282 | +8,879 | 0.00 | 0.00 | -0.00 | buy |
| VANGUARD GROUP INC | 41,981 | 50,286 | +8,305 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 18,153 | 18,891 | +738 | 0.00 | 0.00 | -0.00 | buy |
| Tower Research Capital LLC (TRC) | 1,621 | 1,861 | +240 | 0.00 | 0.00 | -0.00 | buy |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | 0 | 110 | +110 | 0.00 | 0.00 | +0.00 | buy |
| Qube Research & Technologies Ltd | 3 | 103 | +100 | 0.00 | 0.00 | +0.00 | buy |
| Board of Trustees of The Leland Stanford Junior University | 21,127 | 21,127 | 0 | 0.01 | 0.01 | -0.00 | hold |
| CWM, LLC | 200 | 200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Compagnie Lombard Odier SCmA | 400 | 400 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Steward Partners Investment Advisory, LLC | 120 | 120 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Banque Cantonale Vaudoise | 808 | 808 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Covestor Ltd | 1,048 | 1,048 | 0 | 0.01 | 0.00 | -0.00 | hold |
| CITIGROUP INC | 296 | 296 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GROUP ONE TRADING LLC | 3 | 3 | 0 | 0.00 | 0.00 | -0.00 | hold |
| OLD POINT TRUST & FINANCIAL SERVICES N A | 20 | 0 | -20 | 0.00 | 0.00 | -0.00 | sell |
| Knights of Columbus Asset Advisors LLC | 2,417 | 0 | -2,417 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 11,400 | 0 | -11,400 | 0.00 | 0.00 | -0.00 | sell |