| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| RENAISSANCE TECHNOLOGIES LLC | 0 | 21,473 | +21,473 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 18,891 | 37,116 | +18,225 | 0.00 | 0.00 | +0.00 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 147,554 | 162,663 | +15,109 | 0.03 | 0.02 | -0.01 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 14,005 | +14,005 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 50,286 | 53,570 | +3,284 | 0.00 | 0.00 | -0.00 | buy |
| BAKER BROS. ADVISORS LP | 891,335 | 891,335 | 0 | 0.08 | 0.05 | -0.03 | hold |
| Board of Trustees of The Leland Stanford Junior University | 21,127 | 21,127 | 0 | 0.01 | 0.01 | +0.00 | hold |
| CWM, LLC | 200 | 200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Compagnie Lombard Odier SCmA | 400 | 400 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Steward Partners Investment Advisory, LLC | 120 | 120 | 0 | 0.00 | 0.00 | -0.00 | hold |
| SR ONE CAPITAL MANAGEMENT, LP | 443,661 | 443,661 | 0 | 0.98 | 0.51 | -0.48 | hold |
| ADAR1 Capital Management, LLC | 306,067 | 306,067 | 0 | 0.44 | 0.29 | -0.14 | hold |
| CITIGROUP INC | 296 | 296 | 0 | 0.00 | 0.00 | -0.00 | hold |
| GROUP ONE TRADING LLC | 3 | 3 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Covestor Ltd | 1,048 | 969 | -79 | 0.00 | 0.00 | -0.00 | sell |
| Qube Research & Technologies Ltd | 103 | 0 | -103 | 0.00 | 0.00 | -0.00 | sell |
| INTERNATIONAL ASSETS INVESTMENT MANAGEMENT, LLC | 110 | 0 | -110 | 0.00 | 0.00 | -0.00 | sell |
| Banque Cantonale Vaudoise | 808 | 0 | -808 | 0.00 | 0.00 | -0.00 | sell |
| Tower Research Capital LLC (TRC) | 1,861 | 754 | -1,107 | 0.00 | 0.00 | -0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 142,282 | 140,731 | -1,551 | 0.00 | 0.00 | -0.00 | sell |
| Sassicaia Capital Advisers LLC | 12,000 | 0 | -12,000 | 0.34 | 0.00 | -0.34 | sell |
| Virtu Financial LLC | 31,101 | 0 | -31,101 | 0.02 | 0.00 | -0.02 | sell |