| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Cormorant Asset Management, LP | 0 | 603,027 | +603,027 | 0.00 | 0.23 | +0.23 | buy |
| BAKER BROS. ADVISORS LP | 891,335 | 1,201,894 | +310,559 | 0.05 | 0.09 | +0.04 | buy |
| SILVERARC CAPITAL MANAGEMENT, LLC | 0 | 231,070 | +231,070 | 0.00 | 0.36 | +0.36 | buy |
| SR ONE CAPITAL MANAGEMENT, LP | 443,661 | 598,940 | +155,279 | 0.51 | 1.01 | +0.51 | buy |
| AIGH Capital Management LLC | 0 | 121,302 | +121,302 | 0.00 | 0.32 | +0.32 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 162,663 | 178,934 | +16,271 | 0.02 | 0.03 | +0.01 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 37,116 | 47,642 | +10,526 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 296 | 5,676 | +5,380 | 0.00 | 0.00 | +0.00 | buy |
| MAI Capital Management | 0 | 300 | +300 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 98 | +98 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 3 | 22 | +19 | 0.00 | 0.00 | +0.00 | buy |
| VANGUARD GROUP INC | 53,570 | 53,570 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Board of Trustees of The Leland Stanford Junior University | 21,127 | 21,127 | 0 | 0.01 | 0.01 | +0.00 | hold |
| CWM, LLC | 200 | 200 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Compagnie Lombard Odier SCmA | 400 | 400 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Steward Partners Investment Advisory, LLC | 120 | 120 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Covestor Ltd | 969 | 969 | 0 | 0.00 | 0.00 | +0.00 | hold |
| BlackRock, Inc. | 21,356 | 21,356 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Legacy Investment Solutions, LLC | 10 | 10 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Legacy Wealth Managment, LLC/ID | 10 | 10 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Tower Research Capital LLC (TRC) | 754 | 712 | -42 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA INVESTMENTS, LP | 14,005 | 11,877 | -2,128 | 0.00 | 0.00 | +0.00 | sell |
| MILLENNIUM MANAGEMENT LLC | 140,731 | 136,056 | -4,675 | 0.00 | 0.00 | +0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 21,473 | 0 | -21,473 | 0.00 | 0.00 | -0.00 | sell |
| ADAR1 Capital Management, LLC | 306,067 | 220,373 | -85,694 | 0.29 | 0.32 | +0.02 | sell |