| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| FMR LLC | 0 | 2,596,861 | +2,596,861 | 0.00 | 0.00 | +0.00 | buy |
| Durable Capital Partners LP | 0 | 1,740,216 | +1,740,216 | 0.00 | 0.17 | +0.17 | buy |
| Alyeska Investment Group, L.P. | 0 | 1,703,083 | +1,703,083 | 0.00 | 0.08 | +0.08 | buy |
| PFM Health Sciences, LP | 0 | 1,685,727 | +1,685,727 | 0.00 | 1.43 | +1.43 | buy |
| T. Rowe Price Investment Management, Inc. | 0 | 1,603,056 | +1,603,056 | 0.00 | 0.01 | +0.01 | buy |
| Woodline Partners LP | 0 | 1,325,784 | +1,325,784 | 0.00 | 0.10 | +0.10 | buy |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 0 | 840,248 | +840,248 | 0.00 | 0.00 | +0.00 | buy |
| PERCEPTIVE ADVISORS LLC | 0 | 833,333 | +833,333 | 0.00 | 0.33 | +0.33 | buy |
| MARSHALL WACE, LLP | 0 | 650,264 | +650,264 | 0.00 | 0.01 | +0.01 | buy |
| Parkman Healthcare Partners LLC | 0 | 231,099 | +231,099 | 0.00 | 0.30 | +0.30 | buy |
| Schonfeld Strategic Advisors LLC | 0 | 190,156 | +190,156 | 0.00 | 0.01 | +0.01 | buy |
| VANGUARD GROUP INC | 0 | 173,325 | +173,325 | 0.00 | 0.00 | +0.00 | buy |
| Catalio Capital Management, LP | 0 | 166,666 | +166,666 | 0.00 | 0.46 | +0.46 | buy |
| MILLENNIUM MANAGEMENT LLC | 0 | 115,061 | +115,061 | 0.00 | 0.00 | +0.00 | buy |
| GMT CAPITAL CORP | 0 | 98,108 | +98,108 | 0.00 | 0.06 | +0.06 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 0 | 89,299 | +89,299 | 0.00 | 0.00 | +0.00 | buy |
| Ensign Peak Advisors, Inc | 0 | 84,457 | +84,457 | 0.00 | 0.00 | +0.00 | buy |
| C WorldWide Group Holding A/S | 0 | 66,666 | +66,666 | 0.00 | 0.01 | +0.01 | buy |
| BlackRock, Inc. | 0 | 65,918 | +65,918 | 0.00 | 0.00 | +0.00 | buy |
| TD ASSET MANAGEMENT INC | 0 | 53,267 | +53,267 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 41,206 | +41,206 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 0 | 39,356 | +39,356 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 33,912 | +33,912 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 0 | 27,381 | +27,381 | 0.00 | 0.03 | +0.03 | buy |
| STIFEL FINANCIAL CORP | 0 | 22,978 | +22,978 | 0.00 | 0.00 | +0.00 | buy |
| Squarepoint Ops LLC | 0 | 20,992 | +20,992 | 0.00 | 0.00 | +0.00 | buy |
| NATIONAL BANK OF CANADA /FI/ | 0 | 17,602 | +17,602 | 0.00 | 0.00 | +0.00 | buy |
| TWO SIGMA INVESTMENTS, LP | 0 | 16,288 | +16,288 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 0 | 15,461 | +15,461 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 14,818 | +14,818 | 0.00 | 0.00 | +0.00 | buy |
| TUDOR INVESTMENT CORP ET AL | 0 | 12,028 | +12,028 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 0 | 5,419 | +5,419 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 0 | 5,043 | +5,043 | 0.00 | 0.00 | +0.00 | buy |
| PURA VIDA INVESTMENTS, LLC | 0 | 5,000 | +5,000 | 0.00 | 5.72 | +5.72 | buy |
| HUNTINGTON NATIONAL BANK | 0 | 3,820 | +3,820 | 0.00 | 0.00 | +0.00 | buy |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 0 | 2,810 | +2,810 | 0.00 | 0.00 | +0.00 | buy |
| Steward Partners Investment Advisory, LLC | 0 | 1,160 | +1,160 | 0.00 | 0.00 | +0.00 | buy |
| Centricity Wealth Management, LLC | 0 | 563 | +563 | 0.00 | 0.01 | +0.01 | buy |
| BARCLAYS PLC | 0 | 512 | +512 | 0.00 | 0.00 | +0.00 | buy |
| CWM, LLC | 0 | 333 | +333 | 0.00 | 0.00 | +0.00 | buy |
| SBI Securities Co., Ltd. | 0 | 242 | +242 | 0.00 | 0.00 | +0.00 | buy |
| RICHARDS, MERRILL & PETERSON, INC. | 0 | 200 | +200 | 0.00 | 0.00 | +0.00 | buy |
| SIT INVESTMENT ASSOCIATES INC | 0 | 178 | +178 | 0.00 | 0.00 | +0.00 | buy |
| KAYNE ANDERSON RUDNICK INVESTMENT MANAGEMENT LLC | 0 | 66 | +66 | 0.00 | 0.00 | +0.00 | buy |
| Fourth Dimension Wealth, LLC | 0 | 37 | +37 | 0.00 | 0.00 | +0.00 | buy |
| BNP PARIBAS FINANCIAL MARKETS | 0 | 29 | +29 | 0.00 | 0.00 | +0.00 | buy |
| ADIRONDACK TRUST CO | 0 | 18 | +18 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 0 | 5 | +5 | 0.00 | 0.00 | +0.00 | buy |
| TD Waterhouse Canada Inc. | 0 | 3 | +3 | 0.00 | 0.00 | +0.00 | buy |
| US BANCORP \DE\ | 0 | 2 | +2 | 0.00 | 0.00 | +0.00 | buy |
| IFP Advisors, Inc | 0 | 1 | +1 | 0.00 | 0.00 | +0.00 | buy |
| Cranbrook Wealth Management, LLC | 6 | 0 | -6 | 0.00 | 0.00 | -0.00 | sell |
| IFP Advisors, Inc | 34 | 16 | -18 | 0.00 | 0.00 | -0.00 | sell |
| Missouri Trust & Investment Co | 23 | 0 | -23 | 0.00 | 0.00 | -0.00 | sell |
| US BANCORP \DE\ | 38 | 0 | -38 | 0.00 | 0.00 | -0.00 | sell |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 60 | 0 | -60 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 64 | 0 | -64 | 0.00 | 0.00 | -0.00 | sell |
| ADIRONDACK TRUST CO | 280 | 0 | -280 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 464 | 0 | -464 | 0.00 | 0.00 | -0.00 | sell |
| Fourth Dimension Wealth, LLC | 575 | 0 | -575 | 0.00 | 0.00 | -0.00 | sell |
| SBI Securities Co., Ltd. | 959 | 0 | -959 | 0.00 | 0.00 | -0.00 | sell |
| KAYNE ANDERSON RUDNICK INVESTMENT MANAGEMENT LLC | 1,000 | 0 | -1,000 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 1,000 | 0 | -1,000 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 1,388 | 0 | -1,388 | 0.00 | 0.00 | -0.00 | sell |
| FEDERATED HERMES, INC. | 1,472 | 0 | -1,472 | 0.00 | 0.00 | -0.00 | sell |
| SIT INVESTMENT ASSOCIATES INC | 2,668 | 0 | -2,668 | 0.00 | 0.00 | -0.00 | sell |
| RICHARDS, MERRILL & PETERSON, INC. | 3,000 | 0 | -3,000 | 0.00 | 0.00 | -0.00 | sell |
| Centricity Wealth Management, LLC | 8,460 | 0 | -8,460 | 0.01 | 0.00 | -0.01 | sell |
| R Squared Ltd | 9,900 | 0 | -9,900 | 0.01 | 0.00 | -0.01 | sell |
| Qube Research & Technologies Ltd | 10,306 | 0 | -10,306 | 0.00 | 0.00 | -0.00 | sell |
| Scientech Research LLC | 11,543 | 0 | -11,543 | 0.00 | 0.00 | -0.00 | sell |
| LETKO, BROSSEAU & ASSOCIATES INC | 13,550 | 0 | -13,550 | 0.00 | 0.00 | -0.00 | sell |
| Virtu Financial LLC | 13,555 | 0 | -13,555 | 0.00 | 0.00 | -0.00 | sell |
| Sargent Investment Group, LLC | 14,171 | 0 | -14,171 | 0.00 | 0.00 | -0.00 | sell |
| BLB&B Advisors, LLC | 15,985 | 0 | -15,985 | 0.00 | 0.00 | -0.00 | sell |
| Steward Partners Investment Advisory, LLC | 17,400 | 0 | -17,400 | 0.00 | 0.00 | -0.00 | sell |
| HighTower Advisors, LLC | 18,501 | 0 | -18,501 | 0.00 | 0.00 | -0.00 | sell |
| Vanguard Personalized Indexing Management, LLC | 26,855 | 0 | -26,855 | 0.00 | 0.00 | -0.00 | sell |
| Aster Capital Management (DIFC) Ltd | 27,738 | 0 | -27,738 | 0.01 | 0.00 | -0.01 | sell |
| 360 Financial, Inc. | 28,710 | 0 | -28,710 | 0.01 | 0.00 | -0.01 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 39,300 | 0 | -39,300 | 0.00 | 0.00 | -0.00 | sell |
| PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO | 42,164 | 0 | -42,164 | 0.00 | 0.00 | -0.00 | sell |
| TWO SIGMA SECURITIES, LLC | 42,477 | 0 | -42,477 | 0.01 | 0.00 | -0.01 | sell |
| GRIFFIN ASSET MANAGEMENT, INC. | 44,475 | 0 | -44,475 | 0.01 | 0.00 | -0.01 | sell |
| Harbor Advisors LLC | 45,000 | 0 | -45,000 | 0.01 | 0.00 | -0.01 | sell |
| XTX Topco Ltd | 45,315 | 0 | -45,315 | 0.00 | 0.00 | -0.00 | sell |
| NATIONAL BANK OF CANADA /FI/ | 50,044 | 0 | -50,044 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 56,841 | 0 | -56,841 | 0.00 | 0.00 | -0.00 | sell |
| HUNTINGTON NATIONAL BANK | 57,306 | 0 | -57,306 | 0.00 | 0.00 | -0.00 | sell |
| Corient Private Wealth LLC | 61,129 | 0 | -61,129 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 81,766 | 0 | -81,766 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 91,084 | 0 | -91,084 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 99,124 | 0 | -99,124 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 100,000 | 0 | -100,000 | 0.00 | 0.00 | -0.00 | sell |
| GROUP ONE TRADING LLC | 103,106 | 0 | -103,106 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 156,787 | 0 | -156,787 | 0.00 | 0.00 | -0.00 | sell |
| TUDOR INVESTMENT CORP ET AL | 180,444 | 0 | -180,444 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 189,973 | 0 | -189,973 | 0.00 | 0.00 | -0.00 | sell |
| Assenagon Asset Management S.A. | 289,783 | 0 | -289,783 | 0.00 | 0.00 | -0.00 | sell |
| Birchview Capital, LP | 368,766 | 24,584 | -344,182 | 0.33 | 0.24 | -0.10 | sell |