| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| UBS Group AG | 923,060 | 5,037,183 | +4,114,123 | 0.00 | 0.00 | +0.00 | buy |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | 4,937,000 | 7,000,000 | +2,063,000 | 0.62 | 0.34 | -0.28 | buy |
| Pale Fire Capital SE | 1,401,964 | 2,035,362 | +633,398 | 0.24 | 0.06 | -0.18 | buy |
| BlackRock, Inc. | 11,060,645 | 11,430,304 | +369,659 | 0.00 | 0.00 | -0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 3,497,212 | 3,619,682 | +122,470 | 0.00 | 0.00 | -0.00 | buy |
| PRICE T ROWE ASSOCIATES INC /MD/ | 0 | 83,015 | +83,015 | 0.00 | 0.00 | +0.00 | buy |
| Virtu Financial LLC | 0 | 67,305 | +67,305 | 0.00 | 0.00 | +0.00 | buy |
| CIBC Private Wealth Group LLC | 0 | 64,988 | +64,988 | 0.00 | 0.00 | +0.00 | buy |
| AQR CAPITAL MANAGEMENT LLC | 26,839 | 86,963 | +60,124 | 0.00 | 0.00 | -0.00 | buy |
| INTECH INVESTMENT MANAGEMENT LLC | 0 | 57,960 | +57,960 | 0.00 | 0.00 | +0.00 | buy |
| XTX Topco Ltd | 0 | 57,803 | +57,803 | 0.00 | 0.00 | +0.00 | buy |
| Neuberger Berman Group LLC | 0 | 44,667 | +44,667 | 0.00 | 0.00 | +0.00 | buy |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 438,208 | 481,528 | +43,320 | 0.00 | 0.00 | -0.00 | buy |
| FMR LLC | 4,697 | 41,118 | +36,421 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKET INC. | 0 | 35,000 | +35,000 | 0.00 | 0.00 | +0.00 | buy |
| HRT FINANCIAL LP | 0 | 34,482 | +34,482 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 15,726 | 37,866 | +22,140 | 0.00 | 0.00 | +0.00 | buy |
| Mariner, LLC | 0 | 20,267 | +20,267 | 0.00 | 0.00 | +0.00 | buy |
| RENAISSANCE TECHNOLOGIES LLC | 0 | 20,100 | +20,100 | 0.00 | 0.00 | +0.00 | buy |
| Wealthcare Capital Partners, LLC | 0 | 17,845 | +17,845 | 0.00 | 0.00 | +0.00 | buy |
| SEAVIEW INVESTMENT MANAGERS LLC | 0 | 15,063 | +15,063 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 15,587 | 30,550 | +14,963 | 0.00 | 0.00 | -0.00 | buy |
| GTS SECURITIES LLC | 0 | 12,668 | +12,668 | 0.00 | 0.00 | +0.00 | buy |
| Allred Capital Management, LLC | 0 | 11,560 | +11,560 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 178,725 | 188,415 | +9,690 | 0.00 | 0.00 | -0.00 | buy |
| CWM, LLC | 2,085 | 9,328 | +7,243 | 0.00 | 0.00 | -0.00 | buy |
| SBI Securities Co., Ltd. | 1,122 | 6,419 | +5,297 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 96,397 | 100,693 | +4,296 | 0.00 | 0.00 | -0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 30,266 | 33,327 | +3,061 | 0.00 | 0.00 | -0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 22,258 | 25,201 | +2,943 | 0.00 | 0.00 | -0.00 | buy |
| JONES FINANCIAL COMPANIES LLLP | 0 | 1,144 | +1,144 | 0.00 | 0.00 | +0.00 | buy |
| NewEdge Advisors, LLC | 0 | 1,000 | +1,000 | 0.00 | 0.00 | +0.00 | buy |
| Focus Partners Wealth | 25,025 | 25,975 | +950 | 0.00 | 0.00 | -0.00 | buy |
| HBK Sorce Advisory LLC | 10,459 | 11,138 | +679 | 0.00 | 0.00 | -0.00 | buy |
| VOYA INVESTMENT MANAGEMENT LLC | 58,702 | 59,322 | +620 | 0.00 | 0.00 | -0.00 | buy |
| XPONANCE, INC. | 10,760 | 11,046 | +286 | 0.00 | 0.00 | -0.00 | buy |
| AMERIPRISE FINANCIAL INC | 22,042 | 22,239 | +197 | 0.00 | 0.00 | -0.00 | buy |
| HSBC HOLDINGS PLC | 19,751 | 19,925 | +174 | 0.00 | 0.00 | -0.00 | buy |
| Corebridge Financial, Inc. | 83,544 | 83,602 | +58 | 0.00 | 0.00 | -0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 30 | +30 | 0.00 | 0.00 | +0.00 | buy |
| CANTOR FITZGERALD, L. P. | 40,251 | 40,251 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Ameritas Investment Partners, Inc. | 10,167 | 10,167 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 12,176 | 12,176 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 109,570 | 109,570 | 0 | 0.00 | 0.00 | -0.00 | hold |
| MILLENNIUM MANAGEMENT LLC | 258,759 | 258,759 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Sterling Capital Management LLC | 172 | 172 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Bank of New York Mellon Corp | 344,747 | 344,747 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEA Management Company, LLC | 14,986,793 | 14,986,793 | 0 | 0.62 | 0.27 | -0.35 | hold |
| Private Advisor Group, LLC | 18,500 | 18,500 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Point72 Asset Management, L.P. | 650,000 | 650,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Bain Capital Life Sciences Investors, LLC | 16,915,784 | 16,915,784 | 0 | 1.46 | 0.59 | -0.87 | hold |
| LexAurum Advisors, LLC | 16,000 | 16,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Bleichroeder LP | 17,865 | 17,865 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HighMark Wealth Management LLC | 180 | 180 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Blue Trust, Inc. | 8,520 | 8,520 | 0 | 0.00 | 0.00 | -0.00 | hold |
| 1620 INVESTMENT ADVISORS, INC. | 10,000 | 10,000 | 0 | 0.01 | 0.00 | -0.00 | hold |
| LAZARI CAPITAL MANAGEMENT, INC. | 10,000 | 10,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| TD Waterhouse Canada Inc. | 45,000 | 45,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Frazier Financial Advisors, LLC | 10 | 10 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Pathstone Holdings, LLC | 12,637 | 12,637 | 0 | 0.00 | 0.00 | -0.00 | hold |
| RAELIPSKIE PARTNERSHIP | 1,000 | 1,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Police & Firemen's Retirement System of New Jersey | 33,784 | 33,784 | 0 | 0.00 | 0.00 | -0.00 | hold |
| ACORN CAPITAL ADVISORS, LLC | 7,310,650 | 7,310,650 | 0 | 2.89 | 1.17 | -1.72 | hold |
| COMMONWEALTH EQUITY SERVICES, LLC | 25,250 | 25,250 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Legal & General Group Plc | 18,609 | 18,609 | 0 | 0.00 | 0.00 | -0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 51,639 | 51,639 | 0 | 0.00 | 0.00 | -0.00 | hold |
| AMALGAMATED BANK | 4,152 | 4,152 | 0 | 0.00 | 0.00 | -0.00 | hold |
| DEUTSCHE BANK AG\ | 267,628 | 267,628 | 0 | 0.00 | 0.00 | -0.00 | hold |
| EverSource Wealth Advisors, LLC | 41 | 0 | -41 | 0.00 | 0.00 | -0.00 | sell |
| STIFEL FINANCIAL CORP | 75,607 | 75,550 | -57 | 0.00 | 0.00 | -0.00 | sell |
| Clearstead Advisors, LLC | 100 | 0 | -100 | 0.00 | 0.00 | -0.00 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 14,491 | 13,720 | -771 | 0.00 | 0.00 | -0.00 | sell |
| NISA INVESTMENT ADVISORS, LLC | 919 | 0 | -919 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 3,057,297 | 3,055,081 | -2,216 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 62,073 | 58,187 | -3,886 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 29,301 | 19,261 | -10,040 | 0.00 | 0.00 | -0.00 | sell |
| ProShare Advisors LLC | 47,325 | 36,941 | -10,384 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 137,207 | 122,362 | -14,845 | 0.00 | 0.00 | -0.00 | sell |
| Integrated Wealth Concepts LLC | 30,000 | 0 | -30,000 | 0.00 | 0.00 | -0.00 | sell |
| PNC FINANCIAL SERVICES GROUP, INC. | 30,158 | 0 | -30,158 | 0.00 | 0.00 | -0.00 | sell |
| WOLVERINE TRADING, LLC | 39,663 | 0 | -39,663 | 0.00 | 0.00 | -0.00 | sell |
| PRICE T ROWE ASSOCIATES INC /MD/ | 55,996 | 0 | -55,996 | 0.00 | 0.00 | -0.00 | sell |
| Atria Wealth Solutions, Inc. | 60,000 | 0 | -60,000 | 0.00 | 0.00 | -0.00 | sell |
| Vontobel Holding Ltd. | 75,000 | 0 | -75,000 | 0.00 | 0.00 | -0.00 | sell |
| WELLS FARGO & COMPANY/MN | 78,518 | 0 | -78,518 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 191,904 | 111,704 | -80,200 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 266,157 | 185,083 | -81,074 | 0.00 | 0.00 | -0.00 | sell |
| SG Americas Securities, LLC | 183,152 | 91,487 | -91,665 | 0.00 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 1,357,539 | 1,253,815 | -103,724 | 0.00 | 0.00 | -0.00 | sell |
| VANGUARD GROUP INC | 8,200,903 | 8,067,516 | -133,387 | 0.00 | 0.00 | -0.00 | sell |
| Knott David M Jr | 154,071 | 0 | -154,071 | 0.04 | 0.00 | -0.04 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,887,611 | 1,712,361 | -175,250 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 477,638 | 273,865 | -203,773 | 0.00 | 0.00 | -0.00 | sell |
| Ensign Peak Advisors, Inc | 2,546,458 | 2,235,655 | -310,803 | 0.00 | 0.00 | -0.00 | sell |
| ORBIMED ADVISORS LLC | 7,133,515 | 6,776,515 | -357,000 | 0.11 | 0.04 | -0.07 | sell |
| JPMORGAN CHASE & CO | 459,653 | 0 | -459,653 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 583,483 | 0 | -583,483 | 0.00 | 0.00 | -0.00 | sell |
| GROUP ONE TRADING LLC | 797,411 | 172,108 | -625,303 | 0.02 | 0.00 | -0.02 | sell |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 1,264,358 | 252,602 | -1,011,756 | 0.02 | 0.00 | -0.02 | sell |
| Schonfeld Strategic Advisors LLC | 1,392,826 | 335,436 | -1,057,390 | 0.01 | 0.00 | -0.01 | sell |