| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| Tri Locum Partners LP | 4,099,943 | 6,247,500 | +2,147,557 | 2.96 | 2.19 | -0.77 | buy |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 450,000 | 1,559,986 | +1,109,986 | 0.03 | 0.04 | 0.00 | buy |
| Sio Capital Management, LLC | 1,749,003 | 2,599,003 | +850,000 | 1.20 | 0.88 | -0.32 | buy |
| Stonepine Capital Management, LLC | 4,605,263 | 5,273,685 | +668,422 | 80.98 | 1.91 | -79.07 | buy |
| ROYCE & ASSOCIATES LP | 53,490 | 119,006 | +65,516 | 0.00 | 0.00 | +0.00 | buy |
| OneDigital Investment Advisors LLC | 25,150 | 30,315 | +5,165 | 0.00 | 0.00 | -0.00 | buy |
| Total Clarity Wealth Management, Inc. | 145,531 | 11,532 | -133,999 | 0.14 | 0.01 | -0.13 | sell |
| Monashee Investment Management LLC | 572,784 | 427,265 | -145,519 | 0.27 | 0.19 | -0.07 | sell |
| ARMISTICE CAPITAL, LLC | 2,976,000 | 2,356,000 | -620,000 | 0.14 | 0.08 | -0.07 | sell |
| Parkman Healthcare Partners LLC | 3,766,593 | 800,000 | -2,966,593 | 1.27 | 0.16 | -1.11 | sell |