| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0 | 1,887,611 | +1,887,611 | 0.00 | 0.00 | +0.00 | buy |
| GSA CAPITAL PARTNERS LLP | 507,694 | 1,273,635 | +765,941 | 0.03 | 0.07 | +0.04 | buy |
| GROUP ONE TRADING LLC | 125,504 | 797,411 | +671,907 | 0.00 | 0.02 | +0.02 | buy |
| UBS Group AG | 261,126 | 923,060 | +661,934 | 0.00 | 0.00 | +0.00 | buy |
| JANE STREET GROUP, LLC | 0 | 583,483 | +583,483 | 0.00 | 0.00 | +0.00 | buy |
| JPMORGAN CHASE & CO | 0 | 459,653 | +459,653 | 0.00 | 0.00 | +0.00 | buy |
| KINGDON CAPITAL MANAGEMENT, L.L.C. | 4,638,683 | 4,937,000 | +298,317 | 0.46 | 0.62 | +0.16 | buy |
| DEUTSCHE BANK AG\ | 40,577 | 267,628 | +227,051 | 0.00 | 0.00 | +0.00 | buy |
| SIMPLEX TRADING, LLC | 3,455 | 191,904 | +188,449 | 0.00 | 0.00 | +0.00 | buy |
| GOLDMAN SACHS GROUP INC | 292,585 | 477,638 | +185,053 | 0.00 | 0.00 | +0.00 | buy |
| SG Americas Securities, LLC | 55,004 | 183,152 | +128,148 | 0.00 | 0.00 | +0.00 | buy |
| STATE STREET CORP | 2,952,895 | 3,057,297 | +104,402 | 0.00 | 0.00 | +0.00 | buy |
| WELLS FARGO & COMPANY/MN | 0 | 78,518 | +78,518 | 0.00 | 0.00 | +0.00 | buy |
| Atria Wealth Solutions, Inc. | 0 | 60,000 | +60,000 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 3,447,512 | 3,497,212 | +49,700 | 0.00 | 0.00 | +0.00 | buy |
| CANTOR FITZGERALD, L. P. | 0 | 40,251 | +40,251 | 0.00 | 0.00 | +0.00 | buy |
| WOLVERINE TRADING, LLC | 0 | 39,663 | +39,663 | 0.00 | 0.00 | +0.00 | buy |
| NORTHERN TRUST CORP | 1,319,599 | 1,357,539 | +37,940 | 0.00 | 0.00 | -0.00 | buy |
| WEALTH ENHANCEMENT ADVISORY SERVICES, LLC | 0 | 30,266 | +30,266 | 0.00 | 0.00 | +0.00 | buy |
| Integrated Wealth Concepts LLC | 0 | 30,000 | +30,000 | 0.00 | 0.00 | +0.00 | buy |
| Focus Partners Wealth | 0 | 25,025 | +25,025 | 0.00 | 0.00 | +0.00 | buy |
| Point72 Asset Management, L.P. | 625,052 | 650,000 | +24,948 | 0.00 | 0.00 | -0.00 | buy |
| Vanguard Personalized Indexing Management, LLC | 0 | 22,258 | +22,258 | 0.00 | 0.00 | +0.00 | buy |
| AMERIPRISE FINANCIAL INC | 0 | 22,042 | +22,042 | 0.00 | 0.00 | +0.00 | buy |
| CIBC WORLD MARKETS CORP | 0 | 15,726 | +15,726 | 0.00 | 0.00 | +0.00 | buy |
| CITIGROUP INC | 125,080 | 137,207 | +12,127 | 0.00 | 0.00 | +0.00 | buy |
| XPONANCE, INC. | 0 | 10,760 | +10,760 | 0.00 | 0.00 | +0.00 | buy |
| HBK Sorce Advisory LLC | 0 | 10,459 | +10,459 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 10,776 | 15,587 | +4,811 | 0.00 | 0.00 | +0.00 | buy |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 92,266 | 96,397 | +4,131 | 0.00 | 0.00 | +0.00 | buy |
| NISA INVESTMENT ADVISORS, LLC | 314 | 919 | +605 | 0.00 | 0.00 | +0.00 | buy |
| RHUMBLINE ADVISERS | 178,478 | 178,725 | +247 | 0.00 | 0.00 | +0.00 | buy |
| EverSource Wealth Advisors, LLC | 0 | 41 | +41 | 0.00 | 0.00 | +0.00 | buy |
| ORBIMED ADVISORS LLC | 7,133,515 | 7,133,515 | 0 | 0.09 | 0.11 | +0.02 | hold |
| Ameritas Investment Partners, Inc. | 10,167 | 10,167 | 0 | 0.00 | 0.00 | +0.00 | hold |
| VOYA INVESTMENT MANAGEMENT LLC | 58,702 | 58,702 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 12,176 | 12,176 | 0 | 0.00 | 0.00 | +0.00 | hold |
| ALLIANCEBERNSTEIN L.P. | 109,570 | 109,570 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Sterling Capital Management LLC | 172 | 172 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Bank of New York Mellon Corp | 344,747 | 344,747 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Ensign Peak Advisors, Inc | 2,546,458 | 2,546,458 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NEA Management Company, LLC | 14,986,793 | 14,986,793 | 0 | 0.55 | 0.62 | +0.07 | hold |
| Vontobel Holding Ltd. | 75,000 | 75,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Bain Capital Life Sciences Investors, LLC | 16,915,784 | 16,915,784 | 0 | 1.18 | 1.46 | +0.28 | hold |
| LexAurum Advisors, LLC | 16,000 | 16,000 | 0 | 0.00 | 0.00 | -0.00 | hold |
| Bleichroeder LP | 17,865 | 17,865 | 0 | 0.00 | 0.00 | +0.00 | hold |
| HighMark Wealth Management LLC | 180 | 180 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Blue Trust, Inc. | 8,520 | 8,520 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Knott David M Jr | 154,071 | 154,071 | 0 | 0.04 | 0.04 | +0.00 | hold |
| 1620 INVESTMENT ADVISORS, INC. | 10,000 | 10,000 | 0 | 0.00 | 0.01 | +0.00 | hold |
| TD Waterhouse Canada Inc. | 45,000 | 45,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Frazier Financial Advisors, LLC | 10 | 10 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Pathstone Holdings, LLC | 12,637 | 12,637 | 0 | 0.00 | 0.00 | +0.00 | hold |
| RAELIPSKIE PARTNERSHIP | 1,000 | 1,000 | 0 | 0.00 | 0.00 | +0.00 | hold |
| COMMONWEALTH EQUITY SERVICES, LLC | 25,250 | 25,250 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PNC FINANCIAL SERVICES GROUP, INC. | 30,158 | 30,158 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Legal & General Group Plc | 18,609 | 18,609 | 0 | 0.00 | 0.00 | +0.00 | hold |
| PRICE T ROWE ASSOCIATES INC /MD/ | 55,996 | 55,996 | 0 | 0.00 | 0.00 | +0.00 | hold |
| NEW YORK STATE COMMON RETIREMENT FUND | 51,639 | 51,639 | 0 | 0.00 | 0.00 | +0.00 | hold |
| Clearstead Advisors, LLC | 100 | 100 | 0 | 0.00 | 0.00 | +0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 438,208 | 438,208 | 0 | 0.00 | 0.00 | +0.00 | hold |
| AMALGAMATED BANK | 4,152 | 4,152 | 0 | 0.00 | 0.00 | -0.00 | hold |
| HSBC HOLDINGS PLC | 20,092 | 19,751 | -341 | 0.00 | 0.00 | +0.00 | sell |
| True Wealth Design, LLC | 486 | 0 | -486 | 0.00 | 0.00 | -0.00 | sell |
| Arax Advisory Partners | 503 | 0 | -503 | 0.00 | 0.00 | -0.00 | sell |
| EARNED WEALTH ADVISORS, LLC | 760 | 0 | -760 | 0.00 | 0.00 | -0.00 | sell |
| Federation des caisses Desjardins du Quebec | 2,000 | 0 | -2,000 | 0.00 | 0.00 | -0.00 | sell |
| LAZARI CAPITAL MANAGEMENT, INC. | 13,000 | 10,000 | -3,000 | 0.00 | 0.00 | -0.00 | sell |
| PRINCIPAL FINANCIAL GROUP INC | 18,746 | 14,491 | -4,255 | 0.00 | 0.00 | -0.00 | sell |
| AXA S.A. | 3,076,941 | 3,072,143 | -4,798 | 0.01 | 0.01 | +0.00 | sell |
| Corebridge Financial, Inc. | 89,850 | 83,544 | -6,306 | 0.00 | 0.00 | +0.00 | sell |
| FMR LLC | 11,142 | 4,697 | -6,445 | 0.00 | 0.00 | -0.00 | sell |
| Private Advisor Group, LLC | 28,500 | 18,500 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| CWM, LLC | 12,639 | 2,085 | -10,554 | 0.00 | 0.00 | -0.00 | sell |
| BNP PARIBAS FINANCIAL MARKETS | 40,710 | 29,301 | -11,409 | 0.00 | 0.00 | -0.00 | sell |
| BARCLAYS PLC | 277,682 | 266,157 | -11,525 | 0.00 | 0.00 | +0.00 | sell |
| TWO SIGMA SECURITIES, LLC | 12,093 | 0 | -12,093 | 0.00 | 0.00 | -0.00 | sell |
| VICTORY CAPITAL MANAGEMENT INC | 14,927 | 0 | -14,927 | 0.00 | 0.00 | -0.00 | sell |
| ProShare Advisors LLC | 63,506 | 47,325 | -16,181 | 0.00 | 0.00 | -0.00 | sell |
| Bayesian Capital Management, LP | 38,400 | 0 | -38,400 | 0.00 | 0.00 | -0.00 | sell |
| Verition Fund Management LLC | 44,355 | 0 | -44,355 | 0.00 | 0.00 | -0.00 | sell |
| CIBC Private Wealth Group LLC | 45,000 | 0 | -45,000 | 0.00 | 0.00 | -0.00 | sell |
| STIFEL FINANCIAL CORP | 122,448 | 75,607 | -46,841 | 0.00 | 0.00 | -0.00 | sell |
| Invesco Ltd. | 123,780 | 62,073 | -61,707 | 0.00 | 0.00 | -0.00 | sell |
| Amundi | 81,305 | 0 | -81,305 | 0.00 | 0.00 | -0.00 | sell |
| K2 PRINCIPAL FUND, L.P. | 89,158 | 0 | -89,158 | 0.01 | 0.00 | -0.01 | sell |
| MILLENNIUM MANAGEMENT LLC | 363,208 | 258,759 | -104,449 | 0.00 | 0.00 | -0.00 | sell |
| PRELUDE CAPITAL MANAGEMENT, LLC | 105,083 | 0 | -105,083 | 0.01 | 0.00 | -0.01 | sell |
| BlackRock, Inc. | 11,210,671 | 11,060,645 | -150,026 | 0.00 | 0.00 | +0.00 | sell |
| XTX Topco Ltd | 157,642 | 0 | -157,642 | 0.01 | 0.00 | -0.01 | sell |
| Pale Fire Capital SE | 1,602,792 | 1,401,964 | -200,828 | 0.17 | 0.24 | +0.07 | sell |
| VANGUARD GROUP INC | 8,440,730 | 8,200,903 | -239,827 | 0.00 | 0.00 | +0.00 | sell |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 1,549,358 | 1,264,358 | -285,000 | 0.03 | 0.02 | -0.00 | sell |
| Diametric Capital, LP | 288,552 | 0 | -288,552 | 0.10 | 0.00 | -0.10 | sell |
| New Leaf Venture Partners, L.L.C. | 335,000 | 0 | -335,000 | 0.23 | 0.00 | -0.23 | sell |
| Schonfeld Strategic Advisors LLC | 1,920,800 | 1,392,826 | -527,974 | 0.01 | 0.01 | -0.00 | sell |
| AQR CAPITAL MANAGEMENT LLC | 715,722 | 26,839 | -688,883 | 0.00 | 0.00 | -0.00 | sell |
| Parkman Healthcare Partners LLC | 818,727 | 0 | -818,727 | 0.07 | 0.00 | -0.07 | sell |
| Sio Capital Management, LLC | 1,303,508 | 0 | -1,303,508 | 0.39 | 0.00 | -0.39 | sell |
| PERCEPTIVE ADVISORS LLC | 3,545,454 | 0 | -3,545,454 | 0.05 | 0.00 | -0.05 | sell |