| Fund | Previous Shares | Current Shares ▲▼ | Change in Shares ▲▼ | Previous Portfolio Weightage (%) | Current Portfolio Weightage (%) ▲▼ | Change in Weight (%) ▲▼ | Type |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 0 | 6,301,983 | +6,301,983 | 0.00 | 0.00 | +0.00 | buy |
| TANG CAPITAL MANAGEMENT LLC | 6,450,000 | 7,791,936 | +1,341,936 | 1.46 | 0.97 | -0.50 | buy |
| RTW INVESTMENTS, LP | 0 | 1,200,002 | +1,200,002 | 0.00 | 0.02 | +0.02 | buy |
| MILLENNIUM MANAGEMENT LLC | 671,628 | 1,845,403 | +1,173,775 | 0.00 | 0.00 | +0.00 | buy |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 2,000,000 | 3,000,000 | +1,000,000 | 0.01 | 0.01 | -0.00 | buy |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 529,935 | 1,507,717 | +977,782 | 0.01 | 0.01 | +0.00 | buy |
| Congress Park Capital LLC | 233,800 | 1,153,220 | +919,420 | 0.23 | 0.57 | +0.34 | buy |
| Assenagon Asset Management S.A. | 404,674 | 1,238,499 | +833,825 | 0.00 | 0.00 | +0.00 | buy |
| Laurion Capital Management LP | 764,187 | 1,526,387 | +762,200 | 0.05 | 0.06 | +0.01 | buy |
| CITADEL ADVISORS LLC | 0 | 494,643 | +494,643 | 0.00 | 0.00 | +0.00 | buy |
| SUPERSTRING CAPITAL MANAGEMENT LP | 679,403 | 1,151,518 | +472,115 | 0.98 | 1.77 | +0.79 | buy |
| ADAR1 Capital Management, LLC | 155,000 | 572,170 | +417,170 | 0.09 | 0.14 | +0.05 | buy |
| TWO SIGMA INVESTMENTS, LP | 253,773 | 661,947 | +408,174 | 0.00 | 0.00 | +0.00 | buy |
| SEI INVESTMENTS CO | 0 | 382,723 | +382,723 | 0.00 | 0.00 | +0.00 | buy |
| Candriam S.C.A. | 0 | 210,027 | +210,027 | 0.00 | 0.00 | +0.00 | buy |
| Creative Planning | 0 | 107,000 | +107,000 | 0.00 | 0.00 | +0.00 | buy |
| Schonfeld Strategic Advisors LLC | 1,274,507 | 1,375,290 | +100,783 | 0.02 | 0.01 | -0.01 | buy |
| GSA CAPITAL PARTNERS LLP | 148,567 | 229,093 | +80,526 | 0.03 | 0.02 | -0.01 | buy |
| FMR LLC | 183,077 | 242,358 | +59,281 | 0.00 | 0.00 | -0.00 | buy |
| XTX Topco Ltd | 12,553 | 60,586 | +48,033 | 0.00 | 0.01 | +0.00 | buy |
| STIFEL FINANCIAL CORP | 0 | 47,100 | +47,100 | 0.00 | 0.00 | +0.00 | buy |
| Forefront Analytics, LLC | 20,889 | 64,065 | +43,176 | 0.02 | 0.04 | +0.02 | buy |
| Cubist Systematic Strategies, LLC | 41,745 | 82,054 | +40,309 | 0.00 | 0.00 | +0.00 | buy |
| ACADIAN ASSET MANAGEMENT LLC | 2,690,830 | 2,728,569 | +37,739 | 0.02 | 0.01 | -0.01 | buy |
| VANGUARD GROUP INC | 4,857,374 | 4,892,302 | +34,928 | 0.00 | 0.00 | -0.00 | buy |
| Invesco Ltd. | 0 | 23,094 | +23,094 | 0.00 | 0.00 | +0.00 | buy |
| LAZARD ASSET MANAGEMENT LLC | 1,218 | 18,481 | +17,263 | 0.00 | 0.00 | +0.00 | buy |
| Tower Research Capital LLC (TRC) | 0 | 17,039 | +17,039 | 0.00 | 0.00 | +0.00 | buy |
| GROUP ONE TRADING LLC | 637 | 16,964 | +16,327 | 0.00 | 0.00 | +0.00 | buy |
| GEODE CAPITAL MANAGEMENT, LLC | 753,398 | 769,499 | +16,101 | 0.00 | 0.00 | -0.00 | buy |
| Nierenberg Investment Management Company, Inc. | 0 | 12,555 | +12,555 | 0.00 | 0.01 | +0.01 | buy |
| TWO SIGMA ADVISERS, LP | 146,800 | 158,400 | +11,600 | 0.00 | 0.00 | -0.00 | buy |
| Ikarian Capital, LLC | 0 | 8,924 | +8,924 | 0.00 | 0.00 | +0.00 | buy |
| PRUDENTIAL FINANCIAL INC | 31,900 | 36,500 | +4,600 | 0.00 | 0.00 | -0.00 | buy |
| COMMONWEALTH EQUITY SERVICES, LLC | 53,243 | 54,243 | +1,000 | 0.00 | 0.00 | -0.00 | buy |
| Russell Investments Group, Ltd. | 42,798 | 42,814 | +16 | 0.00 | 0.00 | -0.00 | buy |
| INNEALTA CAPITAL, LLC | 0 | 2 | +2 | 0.00 | 0.00 | +0.00 | buy |
| Bank of New York Mellon Corp | 241,981 | 241,982 | +1 | 0.00 | 0.00 | -0.00 | buy |
| RHUMBLINE ADVISERS | 1,291 | 1,291 | 0 | 0.00 | 0.00 | -0.00 | hold |
| BNP PARIBAS FINANCIAL MARKETS | 78 | 78 | 0 | 0.00 | 0.00 | -0.00 | hold |
| IPG Investment Advisors LLC | 12,500 | 12,500 | 0 | 0.01 | 0.00 | -0.00 | hold |
| WestHill Financial Advisors, Inc. | 17,082 | 17,082 | 0 | 0.01 | 0.01 | -0.00 | hold |
| Raleigh Capital Management Inc. | 250 | 250 | 0 | 0.00 | 0.00 | -0.00 | hold |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | 0 | 0 | 0 | 0.00 | 0.00 | 0.00 | hold |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 24,817 | 24,817 | 0 | 0.00 | 0.00 | -0.00 | hold |
| OLD POINT TRUST & FINANCIAL SERVICES N A | 250 | 0 | -250 | 0.00 | 0.00 | -0.00 | sell |
| CORNERCAP INVESTMENT COUNSEL INC | 81,352 | 80,591 | -761 | 0.03 | 0.02 | -0.01 | sell |
| MACQUARIE GROUP LTD | 1,134 | 0 | -1,134 | 0.00 | 0.00 | -0.00 | sell |
| SIMPLEX TRADING, LLC | 6,064 | 3,891 | -2,173 | 0.00 | 0.00 | -0.00 | sell |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | 56,745 | 54,422 | -2,323 | 0.01 | 0.00 | -0.00 | sell |
| NORTHERN TRUST CORP | 134,118 | 131,027 | -3,091 | 0.00 | 0.00 | -0.00 | sell |
| LMR Partners LLP | 18,246 | 15,046 | -3,200 | 0.00 | 0.00 | -0.00 | sell |
| STATE STREET CORP | 267,476 | 263,643 | -3,833 | 0.00 | 0.00 | -0.00 | sell |
| FEDERATED HERMES, INC. | 4,388 | 117 | -4,271 | 0.00 | 0.00 | -0.00 | sell |
| WHITTIER TRUST CO | 6,604 | 2,200 | -4,404 | 0.00 | 0.00 | -0.00 | sell |
| Vontobel Holding Ltd. | 10,000 | 0 | -10,000 | 0.00 | 0.00 | -0.00 | sell |
| D. E. Shaw & Co., Inc. | 10,811 | 0 | -10,811 | 0.00 | 0.00 | -0.00 | sell |
| ExodusPoint Capital Management, LP | 11,049 | 0 | -11,049 | 0.00 | 0.00 | -0.00 | sell |
| Squarepoint Ops LLC | 210,151 | 198,840 | -11,311 | 0.00 | 0.00 | -0.00 | sell |
| HRT FINANCIAL LP | 16,831 | 0 | -16,831 | 0.00 | 0.00 | -0.00 | sell |
| Private Advisor Group, LLC | 69,179 | 52,179 | -17,000 | 0.00 | 0.00 | -0.00 | sell |
| Brevan Howard Capital Management LP | 18,056 | 0 | -18,056 | 0.00 | 0.00 | -0.00 | sell |
| MACKENZIE FINANCIAL CORP | 18,138 | 0 | -18,138 | 0.00 | 0.00 | -0.00 | sell |
| CTC Alternative Strategies, Ltd. | 18,900 | 0 | -18,900 | 0.03 | 0.00 | -0.03 | sell |
| SG Americas Securities, LLC | 26,114 | 0 | -26,114 | 0.00 | 0.00 | -0.00 | sell |
| Formidable Asset Management, LLC | 288,101 | 258,001 | -30,100 | 0.10 | 0.05 | -0.05 | sell |
| Tidal Investments LLC | 288,101 | 258,001 | -30,100 | 0.01 | 0.00 | -0.01 | sell |
| BALYASNY ASSET MANAGEMENT L.P. | 31,921 | 0 | -31,921 | 0.00 | 0.00 | -0.00 | sell |
| OMERS ADMINISTRATION Corp | 35,400 | 0 | -35,400 | 0.00 | 0.00 | -0.00 | sell |
| Jump Financial, LLC | 38,578 | 0 | -38,578 | 0.00 | 0.00 | -0.00 | sell |
| TUDOR INVESTMENT CORP ET AL | 43,865 | 0 | -43,865 | 0.00 | 0.00 | -0.00 | sell |
| RENAISSANCE TECHNOLOGIES LLC | 1,232,800 | 1,183,022 | -49,778 | 0.00 | 0.00 | -0.00 | sell |
| Connor, Clark & Lunn Investment Management Ltd. | 304,334 | 254,220 | -50,114 | 0.00 | 0.00 | -0.00 | sell |
| MARSHALL WACE, LLP | 52,289 | 0 | -52,289 | 0.00 | 0.00 | -0.00 | sell |
| Y-Intercept (Hong Kong) Ltd | 55,595 | 0 | -55,595 | 0.01 | 0.00 | -0.01 | sell |
| LPL Financial LLC | 92,315 | 36,315 | -56,000 | 0.00 | 0.00 | -0.00 | sell |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 443,224 | 369,124 | -74,100 | 0.02 | 0.01 | -0.01 | sell |
| Qube Research & Technologies Ltd | 133,199 | 54,608 | -78,591 | 0.00 | 0.00 | -0.00 | sell |
| Walleye Capital LLC | 85,638 | 0 | -85,638 | 0.00 | 0.00 | -0.00 | sell |
| Point72 Asia (Singapore) Pte. Ltd. | 87,226 | 0 | -87,226 | 0.05 | 0.00 | -0.05 | sell |
| BANK OF MONTREAL /CAN/ | 107,700 | 0 | -107,700 | 0.00 | 0.00 | -0.00 | sell |
| CITIGROUP INC | 123,653 | 0 | -123,653 | 0.00 | 0.00 | -0.00 | sell |
| JANE STREET GROUP, LLC | 183,748 | 0 | -183,748 | 0.00 | 0.00 | -0.00 | sell |
| GOLDMAN SACHS GROUP INC | 293,894 | 109,302 | -184,592 | 0.00 | 0.00 | -0.00 | sell |
| Man Group plc | 191,060 | 0 | -191,060 | 0.00 | 0.00 | -0.00 | sell |
| Clearline Capital LP | 196,583 | 0 | -196,583 | 0.04 | 0.00 | -0.04 | sell |
| BIT Capital GmbH | 250,910 | 0 | -250,910 | 0.05 | 0.00 | -0.05 | sell |
| MORGAN STANLEY | 855,984 | 0 | -855,984 | 0.00 | 0.00 | -0.00 | sell |
| Bronte Capital Management Pty Ltd. | 906,157 | 0 | -906,157 | 0.16 | 0.00 | -0.16 | sell |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 936,778 | 0 | -936,778 | 0.00 | 0.00 | -0.00 | sell |
| BVF INC/IL | 6,595,801 | 5,228,461 | -1,367,340 | 0.40 | 0.18 | -0.22 | sell |
| Sio Capital Management, LLC | 1,598,590 | 0 | -1,598,590 | 1.21 | 0.00 | -1.21 | sell |
| ORBIMED ADVISORS LLC | 3,544,578 | 0 | -3,544,578 | 0.14 | 0.00 | -0.14 | sell |